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The map label for this gene is yheS [H]

Identifier: 222111087

GI number: 222111087

Start: 2017945

End: 2019915

Strand: Direct

Name: yheS [H]

Synonym: Dtpsy_1894

Alternate gene names: 222111087

Gene position: 2017945-2019915 (Clockwise)

Preceding gene: 222111086

Following gene: 222111092

Centisome position: 53.15

GC content: 66.92

Gene sequence:

>1971_bases
ATGATCACCCTGAAGAACGTCACGCTGCGCCGCAGCGCCAAGGTATTGCTCGACGGTGTCTCCGTCACCATCAACCCCGG
GGAGCATGTCGGCCTGGTCGGGCGTAACGGCGCTGGCAAGTCCACGCTGTTTGCGCTGCTCAATGGTTCGCTGCACGAAG
ACGGCGGTGACTTCGTCCTGCCCGCGGCCTGGCGCATGGCCCAGGTGGCGCAAAACATGCCAGAGACGGACGAGTCTGCC
ACCGCCTTCGTGTTGGATGGCGACACTCGCCTGACGGAGCTGCGCCAGGCGCTGCACACGGCCGAGCAGGCGGGTGATGG
CATGGCCATCGCCCAGGCGCACTCCGACCTGGCAGACGCCGGTGCGCACGACGCGACCGCACGCGCGCAGGCGCTCATCC
TGGGGCTGGGCTTTCAGGTGGCGGAGCTGGAGCGCCCGGTCAACAGCTTCTCCGGCGGTTGGCGCATGCGCCTGCAACTG
GCGCGCGCGCTGATGTGCCCCAGCGACCTGCTGCTGCTGGACGAGCCCACCAACCACTTGGACCTGGACGCGCTGGTATG
GCTGGAAGCCTGGCTGCAGCGCTACAACGGTACCTTGGTCGTCATCAGCCACGACCGCGAATTCCTCGACGCCGTGACCC
AGGTCACGCTGCACATCGATAACGCGCGCCTGACCCGCTACGGCGGCAACTACAGCAAGTTCGAGGAGCTGCGCGCCCAG
CAGCTGGAACTGCAGCAGTCGGCCTATGAGCGCCAGCAGGACAAGATCGCGCACCTGCAGAAATTCATCGATCGGTTCAA
GGCCAAGGCCACCAAGGCCAAACAGGCACAAAGCCGCGTGAAGGCGCTGGAGCGCATGGAGAAGATCGCCCCCGTGCTGG
CCTCGGCCGACTTCACCTTCGAGTTCAAGGAGCCGGCCAACCTGCCCAACCCGATGCTGGCCATCACCGACGCGTCCTTC
GGTTATCGCGCCGAGGATGGCAGCGAGACCACCATCCTGCGCCACGTGAACCGCTCGGTACTGGCCGGCCAGCGCATCGG
CATTTTGGGCGCCAACGGCCAGGGCAAGTCCACGCTGGTCAAGACCATCGCCCGCACCATGGCGCCGCTCTCCGGCACCC
TGACCGAGGGCAAGGGCCTGTCGATCGGCTACTTCGCGCAGCAGGAGCTGGACGTGCTGCGTCCCGGCGATAACCCGCTG
GAGCACATGGTGCGCCTGGCGCGCGAACTGGGTGCCCAGGCCCAGGAACCCAGCCGCGAACAGGACCTGCGCAACTTCCT
GGGCAGCTTCAACTTCAGCGGCGACATGGTGCACCAGGCCGTGGGCACCATGAGCGGCGGGGAGAAGGCCCGCCTGGTGC
TGGCCATGATCGTCTGGCAGCGTCCCAACCTGTTGCTGCTGGACGAGCCCACCAATCACCTGGACCTGGCCACGCGCGAG
GCGTTGTCCATGGCGCTCAACGAGTTCGAGGGCACGGTGATGCTGGTCAGCCACGACCGGGCGCTGCTGCGCGCCGTGTG
CGATGAGTTCTGGCTGGTGGGCCGGGGTGCCGTGGCGCCCTTCGACGGCGATCTGGACGATTACCAGCGCTACCTGCTTG
AGGAGTCCAAGCGCCTGCGCGAACTGGCCCGCGCAGCCGAGCAGGCGGTCGTTGCCGAGGCCGCGCCCCCAACCGCCACT
GCCGCCCCTCCCCAGCGCGACGCACGCGAGCAGCGCCGCCAGGAAGCCCAGGCCCGCCAACAGTTGGCCGAGAAAACCCG
CCCCCTCAAGCGAGAGCTTGAAAAAATCGACCAGCGCCTGGAAGCCCTGAACCGGGAAAAAGCGCAGTTGGAAGAACGGC
TCATGCAGCCGTTGCCCCCCGCGGAGATCGCGGAATGCGGGCGGAGGCTCAAGGACTGCGCCGAAGAGGTGACAGCCCTT
GAGGAAAAGTGGCTGGATGTTTCCTCAGCGCTGGAGGAACTGGCGCGCTGA

Upstream 100 bases:

>100_bases
CCAGGTGCTGCTGCTCACGCGCCAGGCCCTGCTCCCACTCGCTCCCGCAAAGTGACGGCGCCGGCCCGGCCGGCCCCCGC
CCCGTCCATTGGTTTGACCC

Downstream 100 bases:

>100_bases
GGGGACACAGGTATTTTTGGTATCTGTATAAAAACAGCCTCCAAGCCTTACGCATAAAGCGCAGACAGCTCCTTTTTCAG
GAGTAAATTCTGGGGATATC

Product: ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MITLKNVTLRRSAKVLLDGVSVTINPGEHVGLVGRNGAGKSTLFALLNGSLHEDGGDFVLPAAWRMAQVAQNMPETDESA
TAFVLDGDTRLTELRQALHTAEQAGDGMAIAQAHSDLADAGAHDATARAQALILGLGFQVAELERPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYNGTLVVISHDREFLDAVTQVTLHIDNARLTRYGGNYSKFEELRAQ
QLELQQSAYERQQDKIAHLQKFIDRFKAKATKAKQAQSRVKALERMEKIAPVLASADFTFEFKEPANLPNPMLAITDASF
GYRAEDGSETTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMAPLSGTLTEGKGLSIGYFAQQELDVLRPGDNPL
EHMVRLARELGAQAQEPSREQDLRNFLGSFNFSGDMVHQAVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATRE
ALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVAPFDGDLDDYQRYLLEESKRLRELARAAEQAVVAEAAPPTAT
AAPPQRDAREQRRQEAQARQQLAEKTRPLKRELEKIDQRLEALNREKAQLEERLMQPLPPAEIAECGRRLKDCAEEVTAL
EEKWLDVSSALEELAR

Sequences:

>Translated_656_residues
MITLKNVTLRRSAKVLLDGVSVTINPGEHVGLVGRNGAGKSTLFALLNGSLHEDGGDFVLPAAWRMAQVAQNMPETDESA
TAFVLDGDTRLTELRQALHTAEQAGDGMAIAQAHSDLADAGAHDATARAQALILGLGFQVAELERPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYNGTLVVISHDREFLDAVTQVTLHIDNARLTRYGGNYSKFEELRAQ
QLELQQSAYERQQDKIAHLQKFIDRFKAKATKAKQAQSRVKALERMEKIAPVLASADFTFEFKEPANLPNPMLAITDASF
GYRAEDGSETTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMAPLSGTLTEGKGLSIGYFAQQELDVLRPGDNPL
EHMVRLARELGAQAQEPSREQDLRNFLGSFNFSGDMVHQAVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATRE
ALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVAPFDGDLDDYQRYLLEESKRLRELARAAEQAVVAEAAPPTAT
AAPPQRDAREQRRQEAQARQQLAEKTRPLKRELEKIDQRLEALNREKAQLEERLMQPLPPAEIAECGRRLKDCAEEVTAL
EEKWLDVSSALEELAR
>Mature_656_residues
MITLKNVTLRRSAKVLLDGVSVTINPGEHVGLVGRNGAGKSTLFALLNGSLHEDGGDFVLPAAWRMAQVAQNMPETDESA
TAFVLDGDTRLTELRQALHTAEQAGDGMAIAQAHSDLADAGAHDATARAQALILGLGFQVAELERPVNSFSGGWRMRLQL
ARALMCPSDLLLLDEPTNHLDLDALVWLEAWLQRYNGTLVVISHDREFLDAVTQVTLHIDNARLTRYGGNYSKFEELRAQ
QLELQQSAYERQQDKIAHLQKFIDRFKAKATKAKQAQSRVKALERMEKIAPVLASADFTFEFKEPANLPNPMLAITDASF
GYRAEDGSETTILRHVNRSVLAGQRIGILGANGQGKSTLVKTIARTMAPLSGTLTEGKGLSIGYFAQQELDVLRPGDNPL
EHMVRLARELGAQAQEPSREQDLRNFLGSFNFSGDMVHQAVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATRE
ALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVAPFDGDLDDYQRYLLEESKRLRELARAAEQAVVAEAAPPTAT
AAPPQRDAREQRRQEAQARQQLAEKTRPLKRELEKIDQRLEALNREKAQLEERLMQPLPPAEIAECGRRLKDCAEEVTAL
EEKWLDVSSALEELAR

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=546, Percent_Identity=36.6300366300366, Blast_Score=338, Evalue=7e-93,
Organism=Homo sapiens, GI10947137, Length=536, Percent_Identity=33.2089552238806, Blast_Score=313, Evalue=3e-85,
Organism=Homo sapiens, GI27881506, Length=536, Percent_Identity=33.2089552238806, Blast_Score=313, Evalue=4e-85,
Organism=Homo sapiens, GI69354671, Length=549, Percent_Identity=34.2440801457195, Blast_Score=258, Evalue=2e-68,
Organism=Homo sapiens, GI10947135, Length=549, Percent_Identity=34.2440801457195, Blast_Score=258, Evalue=2e-68,
Organism=Escherichia coli, GI1789751, Length=660, Percent_Identity=47.8787878787879, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1787041, Length=539, Percent_Identity=32.8385899814471, Blast_Score=295, Evalue=7e-81,
Organism=Escherichia coli, GI1787182, Length=630, Percent_Identity=29.3650793650794, Blast_Score=219, Evalue=6e-58,
Organism=Escherichia coli, GI2367384, Length=559, Percent_Identity=30.0536672629696, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1790190, Length=527, Percent_Identity=22.011385199241, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI87081782, Length=549, Percent_Identity=25.3187613843352, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787758, Length=193, Percent_Identity=31.0880829015544, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788165, Length=201, Percent_Identity=30.3482587064677, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1786803, Length=182, Percent_Identity=28.021978021978, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788506, Length=264, Percent_Identity=21.5909090909091, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994883, Length=231, Percent_Identity=25.5411255411255, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786345, Length=207, Percent_Identity=30.4347826086957, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87081709, Length=219, Percent_Identity=24.6575342465753, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=28.921568627451, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789891, Length=214, Percent_Identity=27.1028037383178, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17553372, Length=547, Percent_Identity=38.2084095063985, Blast_Score=352, Evalue=5e-97,
Organism=Caenorhabditis elegans, GI17555318, Length=564, Percent_Identity=32.8014184397163, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17559834, Length=563, Percent_Identity=32.3268206039076, Blast_Score=288, Evalue=5e-78,
Organism=Caenorhabditis elegans, GI25146777, Length=304, Percent_Identity=24.0131578947368, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=222, Percent_Identity=26.1261261261261, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533592, Length=206, Percent_Identity=27.1844660194175, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=546, Percent_Identity=34.6153846153846, Blast_Score=323, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6320874, Length=546, Percent_Identity=32.967032967033, Blast_Score=289, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6325030, Length=391, Percent_Identity=29.6675191815857, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=27.8350515463918, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=394, Percent_Identity=27.1573604060914, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI24666836, Length=544, Percent_Identity=39.7058823529412, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24642252, Length=538, Percent_Identity=34.0148698884758, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI18859989, Length=538, Percent_Identity=34.0148698884758, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI24641342, Length=550, Percent_Identity=32.5454545454545, Blast_Score=288, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72615; Mature: 72615

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLKNVTLRRSAKVLLDGVSVTINPGEHVGLVGRNGAGKSTLFALLNGSLHEDGGDFVL
CEEECCCHHHHHHHHEEECCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEC
PAAWRMAQVAQNMPETDESATAFVLDGDTRLTELRQALHTAEQAGDGMAIAQAHSDLADA
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHC
GAHDATARAQALILGLGFQVAELERPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLQRYNGTLVVISHDREFLDAVTQVTLHIDNARLTRYGGNYSKFEELRAQ
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHH
QLELQQSAYERQQDKIAHLQKFIDRFKAKATKAKQAQSRVKALERMEKIAPVLASADFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EFKEPANLPNPMLAITDASFGYRAEDGSETTILRHVNRSVLAGQRIGILGANGQGKSTLV
EECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
KTIARTMAPLSGTLTEGKGLSIGYFAQQELDVLRPGDNPLEHMVRLARELGAQAQEPSRE
HHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
QDLRNFLGSFNFSGDMVHQAVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATRE
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVAPFDGDLDDYQRYLLEESKRLR
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
ELARAAEQAVVAEAAPPTATAAPPQRDAREQRRQEAQARQQLAEKTRPLKRELEKIDQRL
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EALNREKAQLEERLMQPLPPAEIAECGRRLKDCAEEVTALEEKWLDVSSALEELAR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MITLKNVTLRRSAKVLLDGVSVTINPGEHVGLVGRNGAGKSTLFALLNGSLHEDGGDFVL
CEEECCCHHHHHHHHEEECCEEEECCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEC
PAAWRMAQVAQNMPETDESATAFVLDGDTRLTELRQALHTAEQAGDGMAIAQAHSDLADA
HHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHC
GAHDATARAQALILGLGFQVAELERPVNSFSGGWRMRLQLARALMCPSDLLLLDEPTNHL
CCCCHHHHHHHHHHHCCCHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
DLDALVWLEAWLQRYNGTLVVISHDREFLDAVTQVTLHIDNARLTRYGGNYSKFEELRAQ
CHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHH
QLELQQSAYERQQDKIAHLQKFIDRFKAKATKAKQAQSRVKALERMEKIAPVLASADFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
EFKEPANLPNPMLAITDASFGYRAEDGSETTILRHVNRSVLAGQRIGILGANGQGKSTLV
EECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHH
KTIARTMAPLSGTLTEGKGLSIGYFAQQELDVLRPGDNPLEHMVRLARELGAQAQEPSRE
HHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCHH
QDLRNFLGSFNFSGDMVHQAVGTMSGGEKARLVLAMIVWQRPNLLLLDEPTNHLDLATRE
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHH
ALSMALNEFEGTVMLVSHDRALLRAVCDEFWLVGRGAVAPFDGDLDDYQRYLLEESKRLR
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
ELARAAEQAVVAEAAPPTATAAPPQRDAREQRRQEAQARQQLAEKTRPLKRELEKIDQRL
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
EALNREKAQLEERLMQPLPPAEIAECGRRLKDCAEEVTALEEKWLDVSSALEELAR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]