Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 222110878

GI number: 222110878

Start: 1786237

End: 1787388

Strand: Direct

Name: mdtA [H]

Synonym: Dtpsy_1685

Alternate gene names: 222110878

Gene position: 1786237-1787388 (Clockwise)

Preceding gene: 222110877

Following gene: 222110879

Centisome position: 47.05

GC content: 69.44

Gene sequence:

>1152_bases
ATGAAATTTCCACGTTTGCAGCGTCGCACGTTGGCGCTGATAGCCGTCATTGCGCCACTGATGGTGCTGTTCGTCTATGT
CGCACTGCGGTCAGGGCCGTTGGCTCCGGTGGCGGTCACGCTGGGCAGCGTGCAATCGCGCGCCATTGCCCCGGCACTCT
CGGGCATAGGCACGGTGCAGGCGCGTTATCTGTACAAGATCGGCCCCACCTTCGCCGGGCGCGTGCAGCGCCTGGACGTG
CAGGTGGGTGACATGGTTCAGGCCGGGCAGGTGCTGGGCGAGATGGACCCAGTGGACCTGGACGACCGCCTGCGCGCACA
GCAGGCGGCCATCAAGAGCGCCGAGGCCGCGCTGCGCCAGGCAGAGGCCAGGCAGAGCTATGCGCAGACCCAGCACCAGC
GCTACGGGCAACTGGTGGCGGTGCGCGGCACCAGCGAGGAAAGCTACGCCACCAAGCAGCAGGAACTGGCCGTGGCGGAC
GCCGCGCTCGCCGCTGCCCGCGAGGATGCGAGCCGTCTGCGCGCTGACTTGCAGGCATTGCGCGCGCAGCGTGGCAACCT
GCGGCTGGTGTCGCCCGTGGCCGGCATGGTGGCTGCGCGCGATGCCGACCCTGGCACGACCGTGGTGGCGGGGCAGGCAG
TGGTGAAGCTCATCGACCCGGCCAGCCTGTGGATCGACACGCGCTTTGACCAGATCACCGCCCAAGGGTTGGCGGCGCAG
CTACCGGCCGAGGTGGTGCTGCGCTCGCGCCGCGGGGACAACCTGGTCGGCAGCGTGCTGCGCGTCGAGCCCCTGGCGGA
CGCGGTGACAGAGGAGACGCTGGCCAAGATCGTCTTCGATGCACCGGTTACACCGCTGCCCCCCGTCGGTGAACTGGCCG
AGGTCACCGTGCGCCTGCCGGCACTGCCCGAAGCGCCCACCATTCCCAATGCGGCCATCCGCTTCGTGGACGGGCAGCGC
GGCGTGTGGAAGCTGGTCAGTGGCAAGCCGCAGTTTGCGCAGGTACGCCTGGGCCGTGCGGACCTCGACGGCCATGTGCA
GGTGCTGGACGGGCTGGCCGTGGGCGACTCCATCGTGGTGTACAGCGAGAGGGCGCTCACGGCGCGTAGCCGCGTGCACG
TGGTTGAGCGCATTGCCGGAGTGGCGCCGTGA

Upstream 100 bases:

>100_bases
GGCTGGTGATGCAGTCGCTGCTCGCCGGTGATGTGCAGCGTATGCGCAAGGATGCCCCGGGGGTCTTTGCCATCTATCGC
CGAGGCATAGGGAGGGTGCA

Downstream 100 bases:

>100_bases
TCAGCCTGGCAGGGCGCGACATTCTGCATGCCTGGGGGAAGTTCGTCTTCACCGGCATCGGCCTGGGCCTGCTGATCGGC
GTGACGCTGACCATGGCGGG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKFPRLQRRTLALIAVIAPLMVLFVYVALRSGPLAPVAVTLGSVQSRAIAPALSGIGTVQARYLYKIGPTFAGRVQRLDV
QVGDMVQAGQVLGEMDPVDLDDRLRAQQAAIKSAEAALRQAEARQSYAQTQHQRYGQLVAVRGTSEESYATKQQELAVAD
AALAAAREDASRLRADLQALRAQRGNLRLVSPVAGMVAARDADPGTTVVAGQAVVKLIDPASLWIDTRFDQITAQGLAAQ
LPAEVVLRSRRGDNLVGSVLRVEPLADAVTEETLAKIVFDAPVTPLPPVGELAEVTVRLPALPEAPTIPNAAIRFVDGQR
GVWKLVSGKPQFAQVRLGRADLDGHVQVLDGLAVGDSIVVYSERALTARSRVHVVERIAGVAP

Sequences:

>Translated_383_residues
MKFPRLQRRTLALIAVIAPLMVLFVYVALRSGPLAPVAVTLGSVQSRAIAPALSGIGTVQARYLYKIGPTFAGRVQRLDV
QVGDMVQAGQVLGEMDPVDLDDRLRAQQAAIKSAEAALRQAEARQSYAQTQHQRYGQLVAVRGTSEESYATKQQELAVAD
AALAAAREDASRLRADLQALRAQRGNLRLVSPVAGMVAARDADPGTTVVAGQAVVKLIDPASLWIDTRFDQITAQGLAAQ
LPAEVVLRSRRGDNLVGSVLRVEPLADAVTEETLAKIVFDAPVTPLPPVGELAEVTVRLPALPEAPTIPNAAIRFVDGQR
GVWKLVSGKPQFAQVRLGRADLDGHVQVLDGLAVGDSIVVYSERALTARSRVHVVERIAGVAP
>Mature_383_residues
MKFPRLQRRTLALIAVIAPLMVLFVYVALRSGPLAPVAVTLGSVQSRAIAPALSGIGTVQARYLYKIGPTFAGRVQRLDV
QVGDMVQAGQVLGEMDPVDLDDRLRAQQAAIKSAEAALRQAEARQSYAQTQHQRYGQLVAVRGTSEESYATKQQELAVAD
AALAAAREDASRLRADLQALRAQRGNLRLVSPVAGMVAARDADPGTTVVAGQAVVKLIDPASLWIDTRFDQITAQGLAAQ
LPAEVVLRSRRGDNLVGSVLRVEPLADAVTEETLAKIVFDAPVTPLPPVGELAEVTVRLPALPEAPTIPNAAIRFVDGQR
GVWKLVSGKPQFAQVRLGRADLDGHVQVLDGLAVGDSIVVYSERALTARSRVHVVERIAGVAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=372, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082036, Length=367, Percent_Identity=26.9754768392371, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40830; Mature: 40830

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPRLQRRTLALIAVIAPLMVLFVYVALRSGPLAPVAVTLGSVQSRAIAPALSGIGTVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
ARYLYKIGPTFAGRVQRLDVQVGDMVQAGQVLGEMDPVDLDDRLRAQQAAIKSAEAALRQ
HHHHEEECCCHHHHHHEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AEARQSYAQTQHQRYGQLVAVRGTSEESYATKQQELAVADAALAAAREDASRLRADLQAL
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQRGNLRLVSPVAGMVAARDADPGTTVVAGQAVVKLIDPASLWIDTRFDQITAQGLAAQ
HHCCCCEEEECHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHEEECHHHHHHHHHHHHH
LPAEVVLRSRRGDNLVGSVLRVEPLADAVTEETLAKIVFDAPVTPLPPVGELAEVTVRLP
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECC
ALPEAPTIPNAAIRFVDGQRGVWKLVSGKPQFAQVRLGRADLDGHVQVLDGLAVGDSIVV
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHCHHCCCEEEE
YSERALTARSRVHVVERIAGVAP
EECHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFPRLQRRTLALIAVIAPLMVLFVYVALRSGPLAPVAVTLGSVQSRAIAPALSGIGTVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
ARYLYKIGPTFAGRVQRLDVQVGDMVQAGQVLGEMDPVDLDDRLRAQQAAIKSAEAALRQ
HHHHEEECCCHHHHHHEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AEARQSYAQTQHQRYGQLVAVRGTSEESYATKQQELAVADAALAAAREDASRLRADLQAL
HHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAQRGNLRLVSPVAGMVAARDADPGTTVVAGQAVVKLIDPASLWIDTRFDQITAQGLAAQ
HHCCCCEEEECHHHHHHHCCCCCCCCEEEEHHHHHHHHCCHHHEEECHHHHHHHHHHHHH
LPAEVVLRSRRGDNLVGSVLRVEPLADAVTEETLAKIVFDAPVTPLPPVGELAEVTVRLP
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECC
ALPEAPTIPNAAIRFVDGQRGVWKLVSGKPQFAQVRLGRADLDGHVQVLDGLAVGDSIVV
CCCCCCCCCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCCCHHHHHCHHCCCEEEE
YSERALTARSRVHVVERIAGVAP
EECHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]