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The map label for this gene is hscB [H]

Identifier: 222110835

GI number: 222110835

Start: 1732393

End: 1732911

Strand: Direct

Name: hscB [H]

Synonym: Dtpsy_1641

Alternate gene names: 222110835

Gene position: 1732393-1732911 (Clockwise)

Preceding gene: 222110834

Following gene: 222110836

Centisome position: 45.63

GC content: 64.93

Gene sequence:

>519_bases
ATGAACCTCCAATCCGACGATTTCGAACTTTTTGGCGTACCACGCCGCTTTGCGCAGGACCGCGACGCCCTGGACGCGCG
GTGGAAGGACCTGCAGCGCGAAGCCCATCCCGACCGGTTTGCGGCGCAGGGCGCCGCCGCCCAGCGTGTGGCGATGCAAT
GGTCGGTGCGCATCAACGAGGCGTACCAACGCCTGAAGGATCCTTTGAAGCGGGCGGCTTACCTTTGCGAACTGGGCGGC
TCGCCCATCCGCGCCGAGGACAACACCGCCATGCCCGCGGCCTTCCTGATGCAGCAGATGGAGTGGCGCGAAGCCCTGGA
TGAGGCCCGCAGTGCTGCGGAGCTTGACGCGCTGGACGACACCACCCATATGGCGCGGCAAGTGGCGTTGGCCCGTTGTG
CGGAACTGCTGGACCAGCATCAGGACTATGCCGGCGCAGCCCGCGAGGTCAGAGCCCTCATGTTCATTGCGCGATTTGCG
CACGACATCGATTCGCGCCGAGAGCAACTGGGACAATAG

Upstream 100 bases:

>100_bases
CGCTGTGGTTGTGGAGAGAGCTTCCGCGTGTGAGCACGCCGTAGGCCGCTTATTGCACAGGACCGCCATCGCCCGCCGCG
CTGGCGGTTTTTTTATTGCC

Downstream 100 bases:

>100_bases
GCGCTTTATTCGGTCACTCCTGCCTGGGCGTGCGCTTGCGGGCCCCGGCTTTTCCACACTCATTTCATGGCGCTTCTGCA
GATTTCCGAACCAGGGCAAT

Product: co-chaperone hsc20

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MNLQSDDFELFGVPRRFAQDRDALDARWKDLQREAHPDRFAAQGAAAQRVAMQWSVRINEAYQRLKDPLKRAAYLCELGG
SPIRAEDNTAMPAAFLMQQMEWREALDEARSAAELDALDDTTHMARQVALARCAELLDQHQDYAGAAREVRALMFIARFA
HDIDSRREQLGQ

Sequences:

>Translated_172_residues
MNLQSDDFELFGVPRRFAQDRDALDARWKDLQREAHPDRFAAQGAAAQRVAMQWSVRINEAYQRLKDPLKRAAYLCELGG
SPIRAEDNTAMPAAFLMQQMEWREALDEARSAAELDALDDTTHMARQVALARCAELLDQHQDYAGAAREVRALMFIARFA
HDIDSRREQLGQ
>Mature_172_residues
MNLQSDDFELFGVPRRFAQDRDALDARWKDLQREAHPDRFAAQGAAAQRVAMQWSVRINEAYQRLKDPLKRAAYLCELGG
SPIRAEDNTAMPAAFLMQQMEWREALDEARSAAELDALDDTTHMARQVALARCAELLDQHQDYAGAAREVRALMFIARFA
HDIDSRREQLGQ

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA [H]

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Escherichia coli, GI1788876, Length=167, Percent_Identity=37.7245508982036, Blast_Score=104, Evalue=3e-24,
Organism=Drosophila melanogaster, GI161084223, Length=164, Percent_Identity=26.219512195122, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640 [H]

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C [H]

EC number: NA

Molecular weight: Translated: 19633; Mature: 19633

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQSDDFELFGVPRRFAQDRDALDARWKDLQREAHPDRFAAQGAAAQRVAMQWSVRINE
CCCCCCCHHHHCCCHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AYQRLKDPLKRAAYLCELGGSPIRAEDNTAMPAAFLMQQMEWREALDEARSAAELDALDD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTHMARQVALARCAELLDQHQDYAGAAREVRALMFIARFAHDIDSRREQLGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLQSDDFELFGVPRRFAQDRDALDARWKDLQREAHPDRFAAQGAAAQRVAMQWSVRINE
CCCCCCCHHHHCCCHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
AYQRLKDPLKRAAYLCELGGSPIRAEDNTAMPAAFLMQQMEWREALDEARSAAELDALDD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTHMARQVALARCAELLDQHQDYAGAAREVRALMFIARFAHDIDSRREQLGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA