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The map label for this gene is ycgM [C]

Identifier: 222110811

GI number: 222110811

Start: 1706091

End: 1706936

Strand: Direct

Name: ycgM [C]

Synonym: Dtpsy_1616

Alternate gene names: 222110811

Gene position: 1706091-1706936 (Clockwise)

Preceding gene: 222110808

Following gene: 222110812

Centisome position: 44.94

GC content: 71.87

Gene sequence:

>846_bases
ATGAAACTCGTCCGCCACGGACAACCCGGCGCGGAGCGCGCCGGCCTGATCGACGCCCAGGGCGTGCTGCGCGACCTGTC
CATGCTGCTGCCGGACATCGGCCCCACGCAGCTGACGCCGCGCACGTTGGCCGCGCTGGCCGCCATCGACGCCGCGCGCC
TGCCCGCGGTGGAACCCGGCACACGCCTGGGCTGCCCCGTGGGCGGTGTCGGCAAGATCGTCTGCGTGGGCCTGAACTAC
GCCGACCATGCGGCCGAGGCCGGCTTGCCCGCGCCGGCAGAGCCCGTGCTGTTCATGAAGGCGACCAGCGCGCTCAGCGG
CCCCACGGACGCCGTGCGCATCCCGCCCGGCGCGCTCAAGACCGACTGGGAGGTGGAGCTGGGCATCGTCATCGGCACGC
GCATGCAGCAGGTGGCCGAGGCCGATGCGCTGGCCCATGTGGCCGGATACGTGCTGGCCAACGACGTGTCCGAGCGCAGC
TACCAGATGGAGCGTGGCGGGCAGTGGGACAAGGGCAAAGGCTGCGACACCTTCGCGCCCGTGGGCCCCTGGCTGGTGAC
CACCGACGAGATTCCCGACCCGCACGCCATAGGGCTGTGGCTGGAGGTGAACGGCCAGCGCATGCAGGACGGCCACACGC
GCAATTTCATCTTCGGCGTGCCCCGTGTGCTGGCCTACATCAGCCAGTTCATGACGCTGGAGCCGGGCGATCTGGTGCTC
ACCGGCACGCCCGCCGGCGTGGGACTGGGACAGAAGCCTGCGCCGCGCTTCTTGCGCGCGGGCGACGTGATGCGGCTGGG
CGCGACGGGGCTGGGCGAGCAGCGGCTGGTCTGCACGGGCGGGTAG

Upstream 100 bases:

>100_bases
GGCCTCGCCATCGCCAAACGCGATGCGGCCATCAGTCGATGCGATGGATGAACGGGATGGCGTGCATAAGATCGTCCCGA
CCAAACCCACGGAGACACCC

Downstream 100 bases:

>100_bases
GGTGTAGCGTGGGAATTTCAAGCCAAATATGCCTGGAACGCTTTCCCATCAAGCGCGAGCAGCTATCATTTTGATAAATC
TCGCACGCACCGCACTTTCT

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLVRHGQPGAERAGLIDAQGVLRDLSMLLPDIGPTQLTPRTLAALAAIDAARLPAVEPGTRLGCPVGGVGKIVCVGLNY
ADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALKTDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERS
YQMERGGQWDKGKGCDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVL
TGTPAGVGLGQKPAPRFLRAGDVMRLGATGLGEQRLVCTGG

Sequences:

>Translated_281_residues
MKLVRHGQPGAERAGLIDAQGVLRDLSMLLPDIGPTQLTPRTLAALAAIDAARLPAVEPGTRLGCPVGGVGKIVCVGLNY
ADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALKTDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERS
YQMERGGQWDKGKGCDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVL
TGTPAGVGLGQKPAPRFLRAGDVMRLGATGLGEQRLVCTGG
>Mature_281_residues
MKLVRHGQPGAERAGLIDAQGVLRDLSMLLPDIGPTQLTPRTLAALAAIDAARLPAVEPGTRLGCPVGGVGKIVCVGLNY
ADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALKTDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERS
YQMERGGQWDKGKGCDTFAPVGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVL
TGTPAGVGLGQKPAPRFLRAGDVMRLGATGLGEQRLVCTGG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=233, Percent_Identity=45.0643776824034, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI40786394, Length=234, Percent_Identity=44.4444444444444, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI66348062, Length=180, Percent_Identity=42.2222222222222, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI215422413, Length=180, Percent_Identity=42.2222222222222, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI13654274, Length=180, Percent_Identity=42.2222222222222, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=40.6593406593407, Blast_Score=131, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=201, Percent_Identity=39.8009950248756, Blast_Score=151, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324161, Length=212, Percent_Identity=29.7169811320755, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28572127, Length=209, Percent_Identity=45.933014354067, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=40, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24663695, Length=279, Percent_Identity=30.1075268817204, Blast_Score=144, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29479; Mature: 29479

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVRHGQPGAERAGLIDAQGVLRDLSMLLPDIGPTQLTPRTLAALAAIDAARLPAVEPG
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALK
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECHHCCCCCCEEECCCCCCC
TDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERGGQWDKGKGCDTFAP
CCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCC
VGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVL
CCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEE
TGTPAGVGLGQKPAPRFLRAGDVMRLGATGLGEQRLVCTGG
ECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEECC
>Mature Secondary Structure
MKLVRHGQPGAERAGLIDAQGVLRDLSMLLPDIGPTQLTPRTLAALAAIDAARLPAVEPG
CCCCCCCCCCCHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TRLGCPVGGVGKIVCVGLNYADHAAEAGLPAPAEPVLFMKATSALSGPTDAVRIPPGALK
CCCCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCCEEEEEECHHCCCCCCEEECCCCCCC
TDWEVELGIVIGTRMQQVAEADALAHVAGYVLANDVSERSYQMERGGQWDKGKGCDTFAP
CCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCC
VGPWLVTTDEIPDPHAIGLWLEVNGQRMQDGHTRNFIFGVPRVLAYISQFMTLEPGDLVL
CCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEE
TGTPAGVGLGQKPAPRFLRAGDVMRLGATGLGEQRLVCTGG
ECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA