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The map label for this gene is insF1 [H]

Identifier: 222110730

GI number: 222110730

Start: 1616079

End: 1616954

Strand: Direct

Name: insF1 [H]

Synonym: Dtpsy_1533

Alternate gene names: 222110730

Gene position: 1616079-1616954 (Clockwise)

Preceding gene: 222110729

Following gene: 222110731

Centisome position: 42.57

GC content: 62.67

Gene sequence:

>876_bases
GTGAAGTACGCATTTATCGAGCGGCATGAACACGAGCACAGCGTGCGCCGCATGTGCAAGATCATGACGGTGCACCCCAG
CGGCTACTACGCCTGGAAGGCCGATCCGGTGAGCCCACGCGCCCAGGACGATCAACGGGTGCTGGGCCTGCTCAAGCACG
CGTGGTTGGAGAGCGGCGGCGTGTACGGCTACCGCAAGCTCACCCTGGACATGCGCGATCTAGGCGAGTCCTGCGGCAAG
CACCGCGTGGCCCGATTGCTCAAACTCGAAGGACTGCGCTCGCAGACCGGCTACCGCCGTCGCCCTGGCATGCGTGGTGG
CAAGCCCGCGGTCGTCGCGCCCAACCACCTGCAGCGCCAGTTCTCCGTGGCGCAGCCCAATCAATCCTGGGTGACCGACA
TCACCTACATCCGCACCCATGAGGGCTGGCTGTACCTGGCCGTGGTGGTCGATCTGTTCTCGCGTCAGGTGGTCGGCTGG
TCAATGGGTAGCCGCATCGATACCGGGCTGGCGCTCGATGCGCTGGTGATGGCCTTGTGGCGTCGTCGACCCGAGCAGCC
AGTCACAGTGCATTCGGATCAAGGCAGTCAATTCACTGGGCATGACTGGCAGGACTTCCTACGCGACCACAAGCTGATCT
GCAGCATGAGCCGTCGCGGCAACTGCCACGACAACGCCGTGGCCGAGAGCTTCTTCCAGTTGCTCAAGCGCGAACGCATC
CGCCGCCAGATCTATCCGACCCGCGATGACGCGAGAGCCGATGTCTTCAACTACATCGAGATGTTCTACAACCCTAAGCG
CCGCCATGGCACTGCCGGAGATACTTCGCCGGTAGAGTTCGAGAGACGCCATTCCCAACGGCTCAAAAGTGTCTAG

Upstream 100 bases:

>100_bases
AAGCCGACGAGATGCGCCGCCTGAAGGCCGAGCTCAAGCGTGTGACCGAGGAGCGCGACATCTTAAAAAAGGCCGCAGCG
TACTTTGCCAAGCAGTCCGG

Downstream 100 bases:

>100_bases
GGAATCCGGGGCGATTCACATCCCGACCCGGAATGGGCTTTTCGCCAGTCCAATGCGCTGCCCTGGCCGTGCCTGGCCGC
ATTGCGCTGGCTGGGAGTGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKYAFIERHEHEHSVRRMCKIMTVHPSGYYAWKADPVSPRAQDDQRVLGLLKHAWLESGGVYGYRKLTLDMRDLGESCGK
HRVARLLKLEGLRSQTGYRRRPGMRGGKPAVVAPNHLQRQFSVAQPNQSWVTDITYIRTHEGWLYLAVVVDLFSRQVVGW
SMGSRIDTGLALDALVMALWRRRPEQPVTVHSDQGSQFTGHDWQDFLRDHKLICSMSRRGNCHDNAVAESFFQLLKRERI
RRQIYPTRDDARADVFNYIEMFYNPKRRHGTAGDTSPVEFERRHSQRLKSV

Sequences:

>Translated_291_residues
MKYAFIERHEHEHSVRRMCKIMTVHPSGYYAWKADPVSPRAQDDQRVLGLLKHAWLESGGVYGYRKLTLDMRDLGESCGK
HRVARLLKLEGLRSQTGYRRRPGMRGGKPAVVAPNHLQRQFSVAQPNQSWVTDITYIRTHEGWLYLAVVVDLFSRQVVGW
SMGSRIDTGLALDALVMALWRRRPEQPVTVHSDQGSQFTGHDWQDFLRDHKLICSMSRRGNCHDNAVAESFFQLLKRERI
RRQIYPTRDDARADVFNYIEMFYNPKRRHGTAGDTSPVEFERRHSQRLKSV
>Mature_291_residues
MKYAFIERHEHEHSVRRMCKIMTVHPSGYYAWKADPVSPRAQDDQRVLGLLKHAWLESGGVYGYRKLTLDMRDLGESCGK
HRVARLLKLEGLRSQTGYRRRPGMRGGKPAVVAPNHLQRQFSVAQPNQSWVTDITYIRTHEGWLYLAVVVDLFSRQVVGW
SMGSRIDTGLALDALVMALWRRRPEQPVTVHSDQGSQFTGHDWQDFLRDHKLICSMSRRGNCHDNAVAESFFQLLKRERI
RRQIYPTRDDARADVFNYIEMFYNPKRRHGTAGDTSPVEFERRHSQRLKSV

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=241, Percent_Identity=34.0248962655602, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1788405, Length=286, Percent_Identity=43.7062937062937, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1787263, Length=286, Percent_Identity=43.7062937062937, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1786753, Length=286, Percent_Identity=43.7062937062937, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1786570, Length=286, Percent_Identity=43.7062937062937, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1786490, Length=286, Percent_Identity=43.7062937062937, Blast_Score=229, Evalue=1e-61,
Organism=Escherichia coli, GI1789981, Length=252, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33889; Mature: 33889

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAFIERHEHEHSVRRMCKIMTVHPSGYYAWKADPVSPRAQDDQRVLGLLKHAWLESGG
CCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
VYGYRKLTLDMRDLGESCGKHRVARLLKLEGLRSQTGYRRRPGMRGGKPAVVAPNHLQRQ
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCEECCHHHHHH
FSVAQPNQSWVTDITYIRTHEGWLYLAVVVDLFSRQVVGWSMGSRIDTGLALDALVMALW
HHCCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RRRPEQPVTVHSDQGSQFTGHDWQDFLRDHKLICSMSRRGNCHDNAVAESFFQLLKRERI
HCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RRQIYPTRDDARADVFNYIEMFYNPKRRHGTAGDTSPVEFERRHSQRLKSV
HHHCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYAFIERHEHEHSVRRMCKIMTVHPSGYYAWKADPVSPRAQDDQRVLGLLKHAWLESGG
CCCCHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
VYGYRKLTLDMRDLGESCGKHRVARLLKLEGLRSQTGYRRRPGMRGGKPAVVAPNHLQRQ
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCCCCCEECCHHHHHH
FSVAQPNQSWVTDITYIRTHEGWLYLAVVVDLFSRQVVGWSMGSRIDTGLALDALVMALW
HHCCCCCCCHHHHEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
RRRPEQPVTVHSDQGSQFTGHDWQDFLRDHKLICSMSRRGNCHDNAVAESFFQLLKRERI
HCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
RRQIYPTRDDARADVFNYIEMFYNPKRRHGTAGDTSPVEFERRHSQRLKSV
HHHCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]