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The map label for this gene is blh [H]

Identifier: 222110610

GI number: 222110610

Start: 1477325

End: 1478227

Strand: Direct

Name: blh [H]

Synonym: Dtpsy_1411

Alternate gene names: 222110610

Gene position: 1477325-1478227 (Clockwise)

Preceding gene: 222110605

Following gene: 222110614

Centisome position: 38.91

GC content: 67.66

Gene sequence:

>903_bases
ATGCCCCACGCCTCCATGCATATCGAGCCCTTCTTCGACCCCGTGACGGGCACCGTGAGCTATGTGCTCGCAGACACCGA
CGCCGGCCAAGCGGCCGTGATCGACCCCGTGCTGGATTTCGAGCCGAAGTCCGGCACGCTGACCAGCGCCTCATCGGACC
GCATCATTGAATACGTGCGCCGCCAGGGCTGGCAGGTGCAGTGGATCCTGGAAACCCACGCACACGCCGACCATCTCTCG
GGCGCGCAGCACATACGCCACCACCTCGGCGGCAAGGTCGCCATCGGCGCGCACATCCGCGCGGTGCAGCAGCTCTTTCG
CAGCGTGTTCCATTTCGAGCGCAGCTTCCTGCCCGACGGCAGCCAGTTCGACCACCTGTTCGAGGACGGCGAGACCTTCC
ATGTCGGCGGGCTGGAGCTGACGGCGCTGCATGTGCCGGGCCATACGCCTGCCGACATGGCCTACCGCGTGGGTGACGAC
GTGTTCGTGGGCGACACGCTGTTCATGCCCGACGTGGGTACGGCCCGCGCGGACTTTCCGGGTGGCGATGCCGCCACGCT
GTACCGCTCCATCCAGCGCCTGCTGGCGCTGCCCGCGCACACCCGACTGCACATGTGCCACGACTATCCGCCCGAGAACC
GCGCACCTGCCTGGGTCAGCACCGTGGCAGAGCAACGCAGCGGCAACATCCATGTGCACGAGGGCGTGACCGAGGCCGCG
TTCGTGCAGATGCGCACCGCGCGGGACGCCACACTGGCGATGCCCACCCTCATCCTGCCTTCGGTGCAGGTCAATGTGCG
CGCCGGCAAGCTGCCGCCCGCGCAGGACGACGGGCGTACCTATATCCAGCTGCCCATCAATGCGTTCCTGAAAGGGGCTG
GCGCGCCGCAGGGCGTGTCGTGA

Upstream 100 bases:

>100_bases
GTGCAAGACAATATGTTTTCATATAATATATCAAAAAATAAACTGTTGTTGGTTGGTGGTGCTGCTTCGGCACTTCCGTC
TTCATTGCGAAAGGACCTTC

Downstream 100 bases:

>100_bases
TGCCGGCGGCGCACCTCTTTGCGCCAGCGGCCGCGTTGCTAAGGGGCGGAGTGGCCGCTGATGAGCGCGAGGTGTTGGGC
CAGCGTGGCAGCCGACAGCT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPHASMHIEPFFDPVTGTVSYVLADTDAGQAAVIDPVLDFEPKSGTLTSASSDRIIEYVRRQGWQVQWILETHAHADHLS
GAQHIRHHLGGKVAIGAHIRAVQQLFRSVFHFERSFLPDGSQFDHLFEDGETFHVGGLELTALHVPGHTPADMAYRVGDD
VFVGDTLFMPDVGTARADFPGGDAATLYRSIQRLLALPAHTRLHMCHDYPPENRAPAWVSTVAEQRSGNIHVHEGVTEAA
FVQMRTARDATLAMPTLILPSVQVNVRAGKLPPAQDDGRTYIQLPINAFLKGAGAPQGVS

Sequences:

>Translated_300_residues
MPHASMHIEPFFDPVTGTVSYVLADTDAGQAAVIDPVLDFEPKSGTLTSASSDRIIEYVRRQGWQVQWILETHAHADHLS
GAQHIRHHLGGKVAIGAHIRAVQQLFRSVFHFERSFLPDGSQFDHLFEDGETFHVGGLELTALHVPGHTPADMAYRVGDD
VFVGDTLFMPDVGTARADFPGGDAATLYRSIQRLLALPAHTRLHMCHDYPPENRAPAWVSTVAEQRSGNIHVHEGVTEAA
FVQMRTARDATLAMPTLILPSVQVNVRAGKLPPAQDDGRTYIQLPINAFLKGAGAPQGVS
>Mature_299_residues
PHASMHIEPFFDPVTGTVSYVLADTDAGQAAVIDPVLDFEPKSGTLTSASSDRIIEYVRRQGWQVQWILETHAHADHLSG
AQHIRHHLGGKVAIGAHIRAVQQLFRSVFHFERSFLPDGSQFDHLFEDGETFHVGGLELTALHVPGHTPADMAYRVGDDV
FVGDTLFMPDVGTARADFPGGDAATLYRSIQRLLALPAHTRLHMCHDYPPENRAPAWVSTVAEQRSGNIHVHEGVTEAAF
VQMRTARDATLAMPTLILPSVQVNVRAGKLPPAQDDGRTYIQLPINAFLKGAGAPQGVS

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=273, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17538952, Length=275, Percent_Identity=25.4545454545455, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221330176, Length=262, Percent_Identity=28.2442748091603, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32737; Mature: 32606

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHASMHIEPFFDPVTGTVSYVLADTDAGQAAVIDPVLDFEPKSGTLTSASSDRIIEYVR
CCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECHHHCCCCCCCCEECCCHHHHHHHHH
RQGWQVQWILETHAHADHLSGAQHIRHHLGGKVAIGAHIRAVQQLFRSVFHFERSFLPDG
HCCCEEEEEEECCCCHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
SQFDHLFEDGETFHVGGLELTALHVPGHTPADMAYRVGDDVFVGDTLFMPDVGTARADFP
CHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHCCCCEEECCEEECCCCCCCCCCCC
GGDAATLYRSIQRLLALPAHTRLHMCHDYPPENRAPAWVSTVAEQRSGNIHVHEGVTEAA
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHH
FVQMRTARDATLAMPTLILPSVQVNVRAGKLPPAQDDGRTYIQLPINAFLKGAGAPQGVS
HHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PHASMHIEPFFDPVTGTVSYVLADTDAGQAAVIDPVLDFEPKSGTLTSASSDRIIEYVR
CCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEECHHHCCCCCCCCEECCCHHHHHHHHH
RQGWQVQWILETHAHADHLSGAQHIRHHLGGKVAIGAHIRAVQQLFRSVFHFERSFLPDG
HCCCEEEEEEECCCCHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCC
SQFDHLFEDGETFHVGGLELTALHVPGHTPADMAYRVGDDVFVGDTLFMPDVGTARADFP
CHHHHHHCCCCEEEECCEEEEEEECCCCCCHHHHHHCCCCEEECCEEECCCCCCCCCCCC
GGDAATLYRSIQRLLALPAHTRLHMCHDYPPENRAPAWVSTVAEQRSGNIHVHEGVTEAA
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCEEEECCCCHHH
FVQMRTARDATLAMPTLILPSVQVNVRAGKLPPAQDDGRTYIQLPINAFLKGAGAPQGVS
HHHHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]