BacMap

Definition	Acidovorax ebreus TPSY chromosome, complete genome.
Accession	NC_011992
Length	3,796,573

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The map label for this gene is phbB [H]

Identifier: 222110511

GI number: 222110511

Start: 1369589

End: 1370335

Strand: Direct

Name: phbB [H]

Synonym: Dtpsy_1310

Alternate gene names: 222110511

Gene position: 1369589-1370335 (Clockwise)

Preceding gene: 222110510

Following gene: 222110512

Centisome position: 36.07

GC content: 65.33

Gene sequence:

>747_bases
ATGAGCAGTTCGGGACGAACCGCCCTGGTCACTGGCGGCAATCGCGGCCTTGGCGCGGCCATTGCCCGCGCGCTGGACGA
CGCGGGCCACCGCGTCATCATCACGCACACGCCCGGCAACGAGAAGGTCGCCGCCTGGCTTGACGCGCAGGACACCAAAG
GCTACCGGTTCACGGCCTACGGCGTCGATGTCGGCGACTGGGAATCGACCCAGGCCTTGGCGCGTCAGATTCAGGCGGAC
GGCCACCACGTTGACATCCTGGTGAACAACGCCGGCATCACCCGCGACGCGACCCTGCGCAAGATGGACAAGGCCGGCTG
GGACGCCGTGCTGCGCACCAACCTGGACTCCATGTTCAATGTCACCAAGCCATTCATCGATCCGATGGTGGAGCGTGGCT
GGGGGCGCATCGTCAACGTCTCGTCCATCAACGGCAGCAAGGGTCAGTTCGGCCAGACCAATTACTCGGCGGCCAAGGCT
GGCGTGCATGGCTTCACCAAGGCGCTGGCGCAGGAGGTGGCACGCAAGGGCGTGACGGTCAACACCGTCTCGCCGGGCTA
TCTGGCCACCGAAATGGTGATGGCGGTGCGCGAGGACGTGCGCCAGAAGGTCATCGAAGCGATTCCGGTGGGTCGCCTCG
GCCAGCCGGATGAGATCGCGGCGCTGGTGGCCTTCATCGCCAGTGACGCTGCTGCTTTCATGACGGGCAGCAACGTGGCG
ATGAACGGTGGCCAGCACATGTCATGA

Upstream 100 bases:

>100_bases
GGCACAGCCTCTTTCGCGCAGTTTTTTCAGCAATGGACGCAGCCCTGGACTGCGCCAGGCGCCGCGCCTCAGGGCAAGGC
CAAAAAGTGAGGAGGCGCAT

Downstream 100 bases:

>100_bases
GTCGGGAGAGCCCGCAGCCCTTGCGGGCGGTTTCCCGCGCGGCAGTCAGCGCCTCCCGGAGGAGTTCCATGTATTCCCGA
TTTCTGGTGCCGCTGGACGG

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSSSGRTALVTGGNRGLGAAIARALDDAGHRVIITHTPGNEKVAAWLDAQDTKGYRFTAYGVDVGDWESTQALARQIQAD
GHHVDILVNNAGITRDATLRKMDKAGWDAVLRTNLDSMFNVTKPFIDPMVERGWGRIVNVSSINGSKGQFGQTNYSAAKA
GVHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDVRQKVIEAIPVGRLGQPDEIAALVAFIASDAAAFMTGSNVA
MNGGQHMS

Sequences:

>Translated_248_residues
MSSSGRTALVTGGNRGLGAAIARALDDAGHRVIITHTPGNEKVAAWLDAQDTKGYRFTAYGVDVGDWESTQALARQIQAD
GHHVDILVNNAGITRDATLRKMDKAGWDAVLRTNLDSMFNVTKPFIDPMVERGWGRIVNVSSINGSKGQFGQTNYSAAKA
GVHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDVRQKVIEAIPVGRLGQPDEIAALVAFIASDAAAFMTGSNVA
MNGGQHMS
>Mature_247_residues
SSSGRTALVTGGNRGLGAAIARALDDAGHRVIITHTPGNEKVAAWLDAQDTKGYRFTAYGVDVGDWESTQALARQIQADG
HHVDILVNNAGITRDATLRKMDKAGWDAVLRTNLDSMFNVTKPFIDPMVERGWGRIVNVSSINGSKGQFGQTNYSAAKAG
VHGFTKALAQEVARKGVTVNTVSPGYLATEMVMAVREDVRQKVIEAIPVGRLGQPDEIAALVAFIASDAAAFMTGSNVAM
NGGQHMS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=37.0967741935484, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.8360655737705, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI19923817, Length=252, Percent_Identity=31.3492063492063, Blast_Score=111, Evalue=7e-25,
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=31.2741312741313, Blast_Score=104, Evalue=7e-23,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=29.0983606557377, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=30.672268907563, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI66933014, Length=176, Percent_Identity=32.3863636363636, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI109715829, Length=239, Percent_Identity=29.7071129707113, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=31.8965517241379, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4758504, Length=270, Percent_Identity=29.6296296296296, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=28.90625, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723750, Length=252, Percent_Identity=25.7936507936508, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=34.0425531914894, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=30.0970873786408, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=27.1604938271605, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19743808, Length=204, Percent_Identity=33.8235294117647, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7657478, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503301, Length=199, Percent_Identity=26.1306532663317, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI83715985, Length=270, Percent_Identity=28.1481481481481, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI25282469, Length=237, Percent_Identity=25.7383966244726, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=194, Percent_Identity=26.2886597938144, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI166795268, Length=204, Percent_Identity=29.9019607843137, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22507405, Length=212, Percent_Identity=28.7735849056604, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=249, Percent_Identity=43.7751004016064, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=35.8267716535433, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=31.8725099601594, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=31.9838056680162, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=29.6747967479675, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=31.5352697095436, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=28.7937743190661, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=31.7073170731707, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=29.1828793774319, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=31.1203319502075, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=39.5918367346939, Blast_Score=178, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=40.8163265306122, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=33.6032388663968, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17568967, Length=237, Percent_Identity=31.2236286919831, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.9160305343511, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=30.8880308880309, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=28.6290322580645, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193203117, Length=196, Percent_Identity=32.1428571428571, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.1853281853282, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=32.2916666666667, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=31.0756972111554, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.0836653386454, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=28.2258064516129, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=28.6821705426357, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=30, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=28.9256198347107, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=28.6259541984733, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.277566539924, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=28.2868525896414, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=26.4367816091954, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=171, Percent_Identity=29.2397660818713, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=27.1698113207547, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=265, Percent_Identity=26.7924528301887, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=270, Percent_Identity=27.037037037037, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=28.2442748091603, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.957528957529, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=24.6212121212121, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=28.3524904214559, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=26.9076305220884, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=26.5917602996255, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17558006, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=240, Percent_Identity=28.75, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320089, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=185, Percent_Identity=25.9459459459459, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=39.7540983606557, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.9683794466403, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=32.156862745098, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=32.6771653543307, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=32.2834645669291, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=28.7449392712551, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=28.9156626506024, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI18859837, Length=248, Percent_Identity=32.6612903225806, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=32.6530612244898, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=31.25, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24644337, Length=199, Percent_Identity=33.1658291457286, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355631, Length=174, Percent_Identity=32.183908045977, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24656154, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922628, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221331218, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24581726, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=28.8659793814433, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281364892, Length=174, Percent_Identity=28.735632183908, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=31.8181818181818, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221331216, Length=207, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI161076933, Length=249, Percent_Identity=29.3172690763052, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584748, Length=249, Percent_Identity=29.3172690763052, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=27.4111675126904, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24641232, Length=215, Percent_Identity=31.1627906976744, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26311; Mature: 26180

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSGRTALVTGGNRGLGAAIARALDDAGHRVIITHTPGNEKVAAWLDAQDTKGYRFTAY
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEE
GVDVGDWESTQALARQIQADGHHVDILVNNAGITRDATLRKMDKAGWDAVLRTNLDSMFN
ECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHH
VTKPFIDPMVERGWGRIVNVSSINGSKGQFGQTNYSAAKAGVHGFTKALAQEVARKGVTV
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NTVSPGYLATEMVMAVREDVRQKVIEAIPVGRLGQPDEIAALVAFIASDAAAFMTGSNVA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHEEECCCEE
MNGGQHMS
ECCCCCCC
>Mature Secondary Structure 
SSSGRTALVTGGNRGLGAAIARALDDAGHRVIITHTPGNEKVAAWLDAQDTKGYRFTAY
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCEEEEEE
GVDVGDWESTQALARQIQADGHHVDILVNNAGITRDATLRKMDKAGWDAVLRTNLDSMFN
ECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHH
VTKPFIDPMVERGWGRIVNVSSINGSKGQFGQTNYSAAKAGVHGFTKALAQEVARKGVTV
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
NTVSPGYLATEMVMAVREDVRQKVIEAIPVGRLGQPDEIAALVAFIASDAAAFMTGSNVA
EECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHEEECCCEE
MNGGQHMS
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]