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The map label for this gene is frr [H]

Identifier: 222110429

GI number: 222110429

Start: 1288283

End: 1288843

Strand: Direct

Name: frr [H]

Synonym: Dtpsy_1226

Alternate gene names: 222110429

Gene position: 1288283-1288843 (Clockwise)

Preceding gene: 222110428

Following gene: 222110430

Centisome position: 33.93

GC content: 61.14

Gene sequence:

>561_bases
ATGACGATTGCCGACATCAAGAAGACGACCGAGGCGAAGATGGACCAGTCCATCGCCGCCTTCAAGAACAACCTGGCCAA
GATCCGCACCGGCCGCGCCAACCCGCAGCTGCTCGACACGATCCATGTCGAGTACTACGGATCCATGGTGCCGTTGTCCC
AGGTGGCCAACGTGGCTTTGCTCGACGCGCGCACCATCAGTGTGCAGCCATGGGAAAAGAACATGGGTGCCAAGATCGAG
AAGGCGATCCGTGAAAGCGATCTGGGGCTGAACCCGGCCTCCATGGGCGACCTGATCCGCGTGCCCATGCCGCCGATGAG
TGAAGAGCGCCGCAAGGAGATGACCAAGCTGGCGCGCAGCGAAGGCGAGGGCGCCAAGGTGGCCATCCGCAACCTGCGCC
GCGATGCCAATGAAGGCGTCAAGAAACTGGTCAAGGACAAGCTCGCCTCCGAGGACGACCAAAAGCGCGCCGAGGCCGAT
GTGCAGAAAACCACCGACAAGCACATTGCAGAGATCGATGCCTTGGTGGCGGCCAAGGAGCAGGAAATCATGGCGATCTG
A

Upstream 100 bases:

>100_bases
GCTGAAGCGCGTGGTGATGGGCGAAGACGAAGGCACGTTGGTGTACGCTTGATGGCTTTGCCGCGCCTGGCCTGATTGCC
CGCTTGCAGAGGAACCACAC

Downstream 100 bases:

>100_bases
TCCGGTTTTGCGGATCGATCCTGGATTCATGCCCACCGTGCAGGGAGCCATTCCCCACCACATTGCCATCGTCATGGATG
GCAACGGCCGCTGGGCGACG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MTIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVALLDARTISVQPWEKNMGAKIE
KAIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARSEGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEAD
VQKTTDKHIAEIDALVAAKEQEIMAI

Sequences:

>Translated_186_residues
MTIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVALLDARTISVQPWEKNMGAKIE
KAIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARSEGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEAD
VQKTTDKHIAEIDALVAAKEQEIMAI
>Mature_185_residues
TIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVALLDARTISVQPWEKNMGAKIEK
AIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARSEGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEADV
QKTTDKHIAEIDALVAAKEQEIMAI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=33.1428571428571, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=54.9450549450549, Blast_Score=208, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20609; Mature: 20478

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCCHH
LDARTISVQPWEKNMGAKIEKAIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARS
CCCEEEEECCCHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEADVQKTTDKHIAEIDALVAAKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMAI
HHHHCC
>Mature Secondary Structure 
TIADIKKTTEAKMDQSIAAFKNNLAKIRTGRANPQLLDTIHVEYYGSMVPLSQVANVAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHCCHH
LDARTISVQPWEKNMGAKIEKAIRESDLGLNPASMGDLIRVPMPPMSEERRKEMTKLARS
CCCEEEEECCCHHHCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGEGAKVAIRNLRRDANEGVKKLVKDKLASEDDQKRAEADVQKTTDKHIAEIDALVAAKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEIMAI
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA