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The map label for this gene is tsf

Identifier: 222110427

GI number: 222110427

Start: 1286558

End: 1287454

Strand: Direct

Name: tsf

Synonym: Dtpsy_1224

Alternate gene names: 222110427

Gene position: 1286558-1287454 (Clockwise)

Preceding gene: 222110426

Following gene: 222110428

Centisome position: 33.89

GC content: 64.33

Gene sequence:

>897_bases
ATGGCTGCAATTACCGCAAGCATGGTTGCCGAACTGCGTGGCAAGACCGATGCCCCCATGATGGAATGCAAGAAGGCCCT
GACCGAGGCCGACGGCGATATGGCCAAGGCCGAAGAGCTGCTGCGCGTCAAGCTGGGCACCAAGGCCGGCAAGGCTGCTT
CCCGCGTGACGGCCGAAGGCGTGGTGGCATCGTTCATCAACGGCAACGTGGGTGCGCTGATCGAAGTGAACAGCGAAACC
GACTTCGTGTCCAAGAACGACAGCTTCATCGCCATGGCCAACGCGGCCGCCAAGCTGGTCGCGGAACACAACCCCGCGGA
CATCGAAGCCCTGGGCCAATTGGCCTATGAGCAGGACGGCTTCGGCCCCACCCTGGAAGATGTACGCAAGGGCCTGATCG
GCAAGATCGGCGAGAACATGTCTTTCCGTCGTTTCAAGCGTTTCAGCGGCTCCAACCTGGCCGCCTACCTGCACGGCTCG
CGCATCGGCGTGGTGGTGGAGTTCGACGGCGATGCCGTGGCCGCCAAGGACGTGGCCATGCATGTGGCCGCCATGAAGCC
CGTGGCGCTGACCAGCGCCGACGTGCCTGCCGACCTGATCGCCAAGGAGCGTGCCGTGGCCGAGGGCAAGGCCGCCGAGT
CCGGCAAGCCAGCCGATATCGCCGCCAAGATGGTCGAAGGCTCGGTGCAGAAGTACCTCAAGGAAGTCTCGCTGGCCGAC
CAGGTCTTCGTGAAGGCCGCCGATGGCAAGCAGACCGTGGCCCAGATGCTCAAGGCCGCCAACACCACAGTGAAGGGCTT
CACCCTGTACGTGGTGGGCGAGGGCATCGAGAAGAAGGTGGACGATTTCGCCGCCGAGGTGGCTGCGCAAGTCGCTGCCG
CCAAGTCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCGCGATGCGTCGCAAAAAAAGCGGGGCCCCTGGTGAGCCCCCTTTTTTTTAGCTTCTGATCCTGTAACGAACTGAAC
TCAAAAACTGGAGAAACACG

Downstream 100 bases:

>100_bases
TAGCGTCTGCCGCCCACGCCCTTCATCCCCCCAGTCCAGCCTTACGGAGAATTGCCCATGACCCTCGCCACGCCAGCCCA
CAAGCGCATCCTGCTCAAGT

Product: elongation factor ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MAAITASMVAELRGKTDAPMMECKKALTEADGDMAKAEELLRVKLGTKAGKAASRVTAEGVVASFINGNVGALIEVNSET
DFVSKNDSFIAMANAAAKLVAEHNPADIEALGQLAYEQDGFGPTLEDVRKGLIGKIGENMSFRRFKRFSGSNLAAYLHGS
RIGVVVEFDGDAVAAKDVAMHVAAMKPVALTSADVPADLIAKERAVAEGKAAESGKPADIAAKMVEGSVQKYLKEVSLAD
QVFVKAADGKQTVAQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKSGA

Sequences:

>Translated_298_residues
MAAITASMVAELRGKTDAPMMECKKALTEADGDMAKAEELLRVKLGTKAGKAASRVTAEGVVASFINGNVGALIEVNSET
DFVSKNDSFIAMANAAAKLVAEHNPADIEALGQLAYEQDGFGPTLEDVRKGLIGKIGENMSFRRFKRFSGSNLAAYLHGS
RIGVVVEFDGDAVAAKDVAMHVAAMKPVALTSADVPADLIAKERAVAEGKAAESGKPADIAAKMVEGSVQKYLKEVSLAD
QVFVKAADGKQTVAQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKSGA
>Mature_297_residues
AAITASMVAELRGKTDAPMMECKKALTEADGDMAKAEELLRVKLGTKAGKAASRVTAEGVVASFINGNVGALIEVNSETD
FVSKNDSFIAMANAAAKLVAEHNPADIEALGQLAYEQDGFGPTLEDVRKGLIGKIGENMSFRRFKRFSGSNLAAYLHGSR
IGVVVEFDGDAVAAKDVAMHVAAMKPVALTSADVPADLIAKERAVAEGKAAESGKPADIAAKMVEGSVQKYLKEVSLADQ
VFVKAADGKQTVAQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKSGA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=230, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786366, Length=290, Percent_Identity=46.2068965517241, Blast_Score=216, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=26.530612244898, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19921466, Length=310, Percent_Identity=27.741935483871, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_ACISJ (A1W917)

Other databases:

- EMBL:   CP000539
- RefSeq:   YP_986818.1
- ProteinModelPortal:   A1W917
- SMR:   A1W917
- STRING:   A1W917
- GeneID:   4674423
- GenomeReviews:   CP000539_GR
- KEGG:   ajs:Ajs_2584
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   A1W917
- ProtClustDB:   PRK09377
- BioCyc:   ASP232721:AJS_2584-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30998; Mature: 30867

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2; PS00238 OPSIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITASMVAELRGKTDAPMMECKKALTEADGDMAKAEELLRVKLGTKAGKAASRVTAEG
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVASFINGNVGALIEVNSETDFVSKNDSFIAMANAAAKLVAEHNPADIEALGQLAYEQDG
HHHHHHCCCCEEEEEECCCCCEECCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCC
FGPTLEDVRKGLIGKIGENMSFRRFKRFSGSNLAAYLHGSRIGVVVEFDGDAVAAKDVAM
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCHHHHHHHH
HVAAMKPVALTSADVPADLIAKERAVAEGKAAESGKPADIAAKMVEGSVQKYLKEVSLAD
HHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVFVKAADGKQTVAQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKSGA
HHHEEECCCHHHHHHHHHHCCCEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AAITASMVAELRGKTDAPMMECKKALTEADGDMAKAEELLRVKLGTKAGKAASRVTAEG
CCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHH
VVASFINGNVGALIEVNSETDFVSKNDSFIAMANAAAKLVAEHNPADIEALGQLAYEQDG
HHHHHHCCCCEEEEEECCCCCEECCCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHCCC
FGPTLEDVRKGLIGKIGENMSFRRFKRFSGSNLAAYLHGSRIGVVVEFDGDAVAAKDVAM
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCHHHHHHHH
HVAAMKPVALTSADVPADLIAKERAVAEGKAAESGKPADIAAKMVEGSVQKYLKEVSLAD
HHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVFVKAADGKQTVAQMLKAANTTVKGFTLYVVGEGIEKKVDDFAAEVAAQVAAAKSGA
HHHEEECCCHHHHHHHHHHCCCEECEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA