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The map label for this gene is tig [H]

Identifier: 222110340

GI number: 222110340

Start: 1183753

End: 1185063

Strand: Direct

Name: tig [H]

Synonym: Dtpsy_1127

Alternate gene names: 222110340

Gene position: 1183753-1185063 (Clockwise)

Preceding gene: 222110339

Following gene: 222110341

Centisome position: 31.18

GC content: 63.08

Gene sequence:

>1311_bases
ATGGCCGTAACTGTTGAAACCCTTGAAAAGCTTGAGCGCAAGATCACGCTGAGCTTGCCCCTGACCACGATCCAGACCGA
AGTGGACGCGCGCCTCAAGCGCCTGGCCCGTACGGTGAAGATGGATGGTTTCCGTCCCGGCAAGGTCCCCATGAGCGTAG
TGGCTCAGCGTTACGGCTATTCGGTGCAATACGAAGTGCTGAACGACAAGGTGGGCGAGGCGTTTGCACAGGCCGCCAAT
GAAGCCAACCTGCGCGTGGCAGGCCAGCCGCGCATCACGGAGAAGGACGGCGCGCCTGAGGGCGAAGTGACTTTCGACGC
CGTGTTCGAGGTGTTCCCCGAGGTCAAGATCGGCGATCTGTCCACCGCGGAAGTCGAGAAGCTCTCCGCCGAAGTGACCG
ACAGCGCCATCGACAAGACCGTGGACATCCTGCGCAAGCAGCGCCGTACCTTCGCGCAGCGTGCCCTGGCCGCTGCTGCA
GAAGACGGCGATCGCGTGACGGTGGATTTCGAGGGCAAGATCGACGGCGAGCCCTTCCAGGGCGGCAAGGCCGAGGACTT
CCAGTTCCTGGTGGGCGAGGGCCAGATGCTCAAGGAATTCGAAGACGCAGTGCGCGGCATGAAGTCGGGCGAGAGCAAGA
CCTTCCCCCTGGCCTTCCCCGAGGACTACCACGGCAAGGACGTGGCTGGCAAGACGGCCGACTTCATGGTGACCGTCAAG
AAGATCGAAGCGGCCCACCTGCCCGAGGTGAATGAGCAACTGGCCAAGTCGCTCGGCATTGCCGACGGCACGGTGGAAGG
CTTGCGCGCCGACATCAAGAAGAACCTGGAGCGCGAAGTCAAATTCCGCCTGCTGGCCCGCAACAAGCAAGCCGTGATGG
ACGCTCTGGTGTCCAAAGCGGAACTGGATCTGCCTAACGCCAGCGTGCAAGCTGAAATTGCCCGCCTGTTGGAAGCTGCA
CGCGCCGACCTCAAGCAGCGCGGCATCAAGGACGCCGACAAGGCCGAAATCCCCGAGGACGTGTTCCGCCCTCAGGCCGA
GCGCCGCGTGCGCCTGGGCCTGGTGGTCGCCGAACTCGTGCGTGCCAATAACCTGCAGGCCAAGCCGGAGCAGCTGAAGG
CCCACGTGGACGAGCTGGCTGCCAGCTACGAGAAGCCTGAGGACGTGGTGCGCTGGTACTTCAGCGACCGCAATCGCCTG
GCTGAGGTGGAAGCCGTGGTCATCGAGAACAATGTGACCGACTTCGTGCTGGGCCAGGCCAAGGTGAACGACAAGGCCGT
GTCCTTCGATGAACTGATGGGCCAGGCCTGA

Upstream 100 bases:

>100_bases
TCGAGTCCCCCCCCGCGCACCAACGTGAGACTTTGGCGGAACGTGGTGCAGGCTTGCACTGCAAGTCGGCACGGTCCACA
TCCAGACACTAGGAACAACC

Downstream 100 bases:

>100_bases
GTAGCTGGCCCTTGCCCCGGGCTTTGACCCAGGGGTGAGGACGAAACCCGGCGGGGCTTGTGCTTTGCGGCACAAGCCCC
AATTCATTTCTGGGTACAGT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MAVTVETLEKLERKITLSLPLTTIQTEVDARLKRLARTVKMDGFRPGKVPMSVVAQRYGYSVQYEVLNDKVGEAFAQAAN
EANLRVAGQPRITEKDGAPEGEVTFDAVFEVFPEVKIGDLSTAEVEKLSAEVTDSAIDKTVDILRKQRRTFAQRALAAAA
EDGDRVTVDFEGKIDGEPFQGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLAFPEDYHGKDVAGKTADFMVTVK
KIEAAHLPEVNEQLAKSLGIADGTVEGLRADIKKNLEREVKFRLLARNKQAVMDALVSKAELDLPNASVQAEIARLLEAA
RADLKQRGIKDADKAEIPEDVFRPQAERRVRLGLVVAELVRANNLQAKPEQLKAHVDELAASYEKPEDVVRWYFSDRNRL
AEVEAVVIENNVTDFVLGQAKVNDKAVSFDELMGQA

Sequences:

>Translated_436_residues
MAVTVETLEKLERKITLSLPLTTIQTEVDARLKRLARTVKMDGFRPGKVPMSVVAQRYGYSVQYEVLNDKVGEAFAQAAN
EANLRVAGQPRITEKDGAPEGEVTFDAVFEVFPEVKIGDLSTAEVEKLSAEVTDSAIDKTVDILRKQRRTFAQRALAAAA
EDGDRVTVDFEGKIDGEPFQGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLAFPEDYHGKDVAGKTADFMVTVK
KIEAAHLPEVNEQLAKSLGIADGTVEGLRADIKKNLEREVKFRLLARNKQAVMDALVSKAELDLPNASVQAEIARLLEAA
RADLKQRGIKDADKAEIPEDVFRPQAERRVRLGLVVAELVRANNLQAKPEQLKAHVDELAASYEKPEDVVRWYFSDRNRL
AEVEAVVIENNVTDFVLGQAKVNDKAVSFDELMGQA
>Mature_435_residues
AVTVETLEKLERKITLSLPLTTIQTEVDARLKRLARTVKMDGFRPGKVPMSVVAQRYGYSVQYEVLNDKVGEAFAQAANE
ANLRVAGQPRITEKDGAPEGEVTFDAVFEVFPEVKIGDLSTAEVEKLSAEVTDSAIDKTVDILRKQRRTFAQRALAAAAE
DGDRVTVDFEGKIDGEPFQGGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLAFPEDYHGKDVAGKTADFMVTVKK
IEAAHLPEVNEQLAKSLGIADGTVEGLRADIKKNLEREVKFRLLARNKQAVMDALVSKAELDLPNASVQAEIARLLEAAR
ADLKQRGIKDADKAEIPEDVFRPQAERRVRLGLVVAELVRANNLQAKPEQLKAHVDELAASYEKPEDVVRWYFSDRNRLA
EVEAVVIENNVTDFVLGQAKVNDKAVSFDELMGQA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=436, Percent_Identity=40.1376146788991, Blast_Score=332, Evalue=4e-92,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48173; Mature: 48042

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTVETLEKLERKITLSLPLTTIQTEVDARLKRLARTVKMDGFRPGKVPMSVVAQRYGY
CEEEHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
SVQYEVLNDKVGEAFAQAANEANLRVAGQPRITEKDGAPEGEVTFDAVFEVFPEVKIGDL
EEEEEHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCEECCC
STAEVEKLSAEVTDSAIDKTVDILRKQRRTFAQRALAAAAEDGDRVTVDFEGKIDGEPFQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
GGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLAFPEDYHGKDVAGKTADFMVTVK
CCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCHHHEEEHH
KIEAAHLPEVNEQLAKSLGIADGTVEGLRADIKKNLEREVKFRLLARNKQAVMDALVSKA
HHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELDLPNASVQAEIARLLEAARADLKQRGIKDADKAEIPEDVFRPQAERRVRLGLVVAELV
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHH
RANNLQAKPEQLKAHVDELAASYEKPEDVVRWYFSDRNRLAEVEAVVIENNVTDFVLGQA
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEEEEECCCCHHEECCC
KVNDKAVSFDELMGQA
CCCCCCCCHHHHHCCC
>Mature Secondary Structure 
AVTVETLEKLERKITLSLPLTTIQTEVDARLKRLARTVKMDGFRPGKVPMSVVAQRYGY
EEEHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
SVQYEVLNDKVGEAFAQAANEANLRVAGQPRITEKDGAPEGEVTFDAVFEVFPEVKIGDL
EEEEEHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCEECCC
STAEVEKLSAEVTDSAIDKTVDILRKQRRTFAQRALAAAAEDGDRVTVDFEGKIDGEPFQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
GGKAEDFQFLVGEGQMLKEFEDAVRGMKSGESKTFPLAFPEDYHGKDVAGKTADFMVTVK
CCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCHHHEEEHH
KIEAAHLPEVNEQLAKSLGIADGTVEGLRADIKKNLEREVKFRLLARNKQAVMDALVSKA
HHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELDLPNASVQAEIARLLEAARADLKQRGIKDADKAEIPEDVFRPQAERRVRLGLVVAELV
HCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHHHH
RANNLQAKPEQLKAHVDELAASYEKPEDVVRWYFSDRNRLAEVEAVVIENNVTDFVLGQA
HHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHEEEEEECCCCHHEECCC
KVNDKAVSFDELMGQA
CCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA