Click here to switch to the map view.

The map label for this gene is nuoG [H]

Identifier: 222110092

GI number: 222110092

Start: 901219

End: 903351

Strand: Direct

Name: nuoG [H]

Synonym: Dtpsy_0878

Alternate gene names: 222110092

Gene position: 901219-903351 (Clockwise)

Preceding gene: 222110091

Following gene: 222110093

Centisome position: 23.74

GC content: 63.34

Gene sequence:

>2133_bases
ATGGTTGAAATCGAACTGGACGGGAAGAAGGTAGAAGTCACCGAAGGCTGCATGGTGATGCATGCGGCCGAGAAGGTGGG
TACCTACATTCCCCATTTCTGCTACCACAAGAAGCTTTCCATTGCCGCCAATTGCCGCATGTGCCTGGTGGAGGTGGAGA
AGGCCCCCAAGCCCCTACCCGCATGCGCCACACCCGTGACGCAGGGCATGATCGTGCGCACCAAGAGCGACAAGGCGATC
AAGGCCCAGCAGTCGGTGATGGAGTTCCTGCTCATCAATCACCCGCTGGACTGCCCCATCTGTGACCAGGGCGGCGAATG
CCAGTTGCAGGATCTGGCCGTAGGTTATGGCGGCGATTCCTCGCGCTACGGCGAGGAAAAGCGCGTGGTGGCGCACAAGG
ACGTGGGCCCACTGATCTCCATGGAAGAGATGACCCGCTGCATCCATTGCACGCGTTGCGTTCGTTTCGGCCAGGAAATC
GCAGGCGTGATGGAACTCGGCATGGTGAACCGCGGCGAGCATTCGGAGATCACGACCGTGATCGGCGATACCGTCGACTC
GGAACTGTCGGGCAACATGATCGACCTGTGCCCGGTGGGGGCGCTGACCAGCAAGCCCTTCCGCTACAGCGCCCGCACGT
GGGAACTGTCTCGCCGCAAATCCGTGAGTCCGCACGACTCCACGGGCGCCAATCTCATTGTGCAGGTCAAGAACCACAAG
GTCATGCGCGTCGTCCCGTTCGAGAACGAGGATGTCAACGAGTGCTGGATTGCTGATCGCGACCGTTTTTCCTATGAGGC
ATTGAATTCCCCCGACCGCCTGACACGTCCGATGCTCAAACAGGGCGGGGAGTGGAAGGAAGTCGATTGGCAGACGGCTC
TGGAATATGTGGCCAACGGTCTGCGGTGCGTCAAAACCGAGCACGGCGCCCAGAGCATCGGAGCGCTGGTAAGCCCGCAC
AGCACAGTAGAAGAGTTGTTCCTGGCCGGCGCGCTGATGCGCGGGTTGGGTAGCGACAACATCGACCACCGTCTGCGCCA
TGCGGAGTTCGGCAAGGCCGAAGGTGTGCGCTGGCTGGGGACGTCCATCGCATCCCTGAGCACGCTGCAGTCCGTGTTGG
TCGTTGGCTCGAATCTGCGCAAGGACCATCCCTTGTTTGCACAGCGAATTCGGCAGGCAGCGCGCCATGGGTGTGCGGTA
AGCGCTATTAATTCAGTAGCAAATGATTGGGCTATTCCGAATGTCCGCACCAAGCTGGCCCCAGCGGCCGGCTGGAGCAC
GGCGCTGGCGGAAGTCGCAGCCGCCATCGCTGCAGAGAAGGGCGTGGCTGCCCCCGTGCAAGGGGCTGCCACCAGCGAAG
AAGCCCGGGCCATTGCTGCTGCATTGCTGACGGGGGAGCGCAAAGCCATTCTGCTGGGCAATGGTGCTGCCCATCATGCC
CAAGCGTCGAGCCTGCTGGCGCTGGCGCAGTGGATCGGTGCCCAGACCGGAGCGACGGTGGGTTACCTGACGGAGGCCGC
CAATACGGTCGGTGCGCAGTTCGTGGGTGCGCAACCCCAAGAGGGCGGGCTGAACGCTGCACAAATGCTGGATGGCCGCC
TGAAGGCAGCCCTGCTGCTGAATGTGGAGCCTGAGCACGACTCCGCCCTGGGTGCTGCAGCGGCTCAGGCTTTGGCGCAG
ACCGACATGGTCGTCACGCTGAGCCCGTTCAAGACCAACCTCGAGTTCAGCGACGTGCTGCTGCCGATCGCTCCGTTCTC
CGAGACCTCGGGCAGTTTCGTCAACGCCGAAGGGCGCCTGCAGAGCTTCCATGCCGTGGTCAAGCCGGCCGGTGAGGCGC
GTCCTGCGTGGAAGGTATTGCGCGTGCTGGGCAATCTGCTCGGCCTGGAAGGCATGGACTACGAGACGTCCCAGGACGTG
CTGGTCCGTGCGACCGGCAAGCCCGCAGGTGAGTGCACGCAGCTGCCGGCGGAGCGCCTGAGCAACGCCACATCGGCCGA
GCCGAAGCTGGGCGGCGAGTGTGCTGAACCCGTCGTGGCAGCCATCTATCAGCTCGACAGCCTGGTGCGCCGCGCACCGT
CGCTGCAACTGACTGCCGACGCGCGCGCGGCACGTGAAGGAGTCGCCGCATGA

Upstream 100 bases:

>100_bases
CGCCATGCTCAAGCATTTCCGTCCGGAGTTTGAAGCGCTGATCCGAAACGCCCACCCATCGGGTTCCACCCCCGCCAGCG
CCTGAACGCGAGTACAGCAT

Downstream 100 bases:

>100_bases
TCGATGCAATCTACAACGGCGGCCTCAATCTGGTTGCGGCCGGATGGTGGACCGGGGTGGCTTGGCCCGTACTCTGGATC
CTGGTCAAGATCGTCTGCAT

Product: NADH dehydrogenase subunit g

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 710; Mature: 710

Protein sequence:

>710_residues
MVEIELDGKKVEVTEGCMVMHAAEKVGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGDSSRYGEEKRVVAHKDVGPLISMEEMTRCIHCTRCVRFGQEI
AGVMELGMVNRGEHSEITTVIGDTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNSPDRLTRPMLKQGGEWKEVDWQTALEYVANGLRCVKTEHGAQSIGALVSPH
STVEELFLAGALMRGLGSDNIDHRLRHAEFGKAEGVRWLGTSIASLSTLQSVLVVGSNLRKDHPLFAQRIRQAARHGCAV
SAINSVANDWAIPNVRTKLAPAAGWSTALAEVAAAIAAEKGVAAPVQGAATSEEARAIAAALLTGERKAILLGNGAAHHA
QASSLLALAQWIGAQTGATVGYLTEAANTVGAQFVGAQPQEGGLNAAQMLDGRLKAALLLNVEPEHDSALGAAAAQALAQ
TDMVVTLSPFKTNLEFSDVLLPIAPFSETSGSFVNAEGRLQSFHAVVKPAGEARPAWKVLRVLGNLLGLEGMDYETSQDV
LVRATGKPAGECTQLPAERLSNATSAEPKLGGECAEPVVAAIYQLDSLVRRAPSLQLTADARAAREGVAA

Sequences:

>Translated_710_residues
MVEIELDGKKVEVTEGCMVMHAAEKVGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGDSSRYGEEKRVVAHKDVGPLISMEEMTRCIHCTRCVRFGQEI
AGVMELGMVNRGEHSEITTVIGDTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNSPDRLTRPMLKQGGEWKEVDWQTALEYVANGLRCVKTEHGAQSIGALVSPH
STVEELFLAGALMRGLGSDNIDHRLRHAEFGKAEGVRWLGTSIASLSTLQSVLVVGSNLRKDHPLFAQRIRQAARHGCAV
SAINSVANDWAIPNVRTKLAPAAGWSTALAEVAAAIAAEKGVAAPVQGAATSEEARAIAAALLTGERKAILLGNGAAHHA
QASSLLALAQWIGAQTGATVGYLTEAANTVGAQFVGAQPQEGGLNAAQMLDGRLKAALLLNVEPEHDSALGAAAAQALAQ
TDMVVTLSPFKTNLEFSDVLLPIAPFSETSGSFVNAEGRLQSFHAVVKPAGEARPAWKVLRVLGNLLGLEGMDYETSQDV
LVRATGKPAGECTQLPAERLSNATSAEPKLGGECAEPVVAAIYQLDSLVRRAPSLQLTADARAAREGVAA
>Mature_710_residues
MVEIELDGKKVEVTEGCMVMHAAEKVGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLPACATPVTQGMIVRTKSDKAI
KAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGDSSRYGEEKRVVAHKDVGPLISMEEMTRCIHCTRCVRFGQEI
AGVMELGMVNRGEHSEITTVIGDTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
VMRVVPFENEDVNECWIADRDRFSYEALNSPDRLTRPMLKQGGEWKEVDWQTALEYVANGLRCVKTEHGAQSIGALVSPH
STVEELFLAGALMRGLGSDNIDHRLRHAEFGKAEGVRWLGTSIASLSTLQSVLVVGSNLRKDHPLFAQRIRQAARHGCAV
SAINSVANDWAIPNVRTKLAPAAGWSTALAEVAAAIAAEKGVAAPVQGAATSEEARAIAAALLTGERKAILLGNGAAHHA
QASSLLALAQWIGAQTGATVGYLTEAANTVGAQFVGAQPQEGGLNAAQMLDGRLKAALLLNVEPEHDSALGAAAAQALAQ
TDMVVTLSPFKTNLEFSDVLLPIAPFSETSGSFVNAEGRLQSFHAVVKPAGEARPAWKVLRVLGNLLGLEGMDYETSQDV
LVRATGKPAGECTQLPAERLSNATSAEPKLGGECAEPVVAAIYQLDSLVRRAPSLQLTADARAAREGVAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=657, Percent_Identity=36.8340943683409, Blast_Score=391, Evalue=1e-108,
Organism=Escherichia coli, GI145693161, Length=654, Percent_Identity=29.8165137614679, Blast_Score=234, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI17565758, Length=646, Percent_Identity=36.3777089783282, Blast_Score=368, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI32566231, Length=619, Percent_Identity=36.5105008077544, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI193209088, Length=252, Percent_Identity=51.1904761904762, Blast_Score=272, Evalue=4e-73,
Organism=Drosophila melanogaster, GI24640559, Length=654, Percent_Identity=37.9204892966361, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24640557, Length=654, Percent_Identity=37.9204892966361, Blast_Score=382, Evalue=1e-106,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 75833; Mature: 75833

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEIELDGKKVEVTEGCMVMHAAEKVGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLP
CEEEEECCCEEEECCCCHHHHHHHHHHHHCCHHHHHCCCEECCCCEEEEEEHHCCCCCCC
ACATPVTQGMIVRTKSDKAIKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGDS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCC
SRYGEEKRVVAHKDVGPLISMEEMTRCIHCTRCVRFGQEIAGVMELGMVNRGEHSEITTV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IGDTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
HCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCCCEEEEEEECCE
VMRVVPFENEDVNECWIADRDRFSYEALNSPDRLTRPMLKQGGEWKEVDWQTALEYVANG
EEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LRCVKTEHGAQSIGALVSPHSTVEELFLAGALMRGLGSDNIDHRLRHAEFGKAEGVRWLG
CEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHH
TSIASLSTLQSVLVVGSNLRKDHPLFAQRIRQAARHGCAVSAINSVANDWAIPNVRTKLA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCC
PAAGWSTALAEVAAAIAAEKGVAAPVQGAATSEEARAIAAALLTGERKAILLGNGAAHHA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHH
QASSLLALAQWIGAQTGATVGYLTEAANTVGAQFVGAQPQEGGLNAAQMLDGRLKAALLL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEE
NVEPEHDSALGAAAAQALAQTDMVVTLSPFKTNLEFSDVLLPIAPFSETSGSFVNAEGRL
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHEEEECCCCCCCCCCEECCCCHH
QSFHAVVKPAGEARPAWKVLRVLGNLLGLEGMDYETSQDVLVRATGKPAGECTQLPAERL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHCCCHHHH
SNATSAEPKLGGECAEPVVAAIYQLDSLVRRAPSLQLTADARAAREGVAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCC
>Mature Secondary Structure
MVEIELDGKKVEVTEGCMVMHAAEKVGTYIPHFCYHKKLSIAANCRMCLVEVEKAPKPLP
CEEEEECCCEEEECCCCHHHHHHHHHHHHCCHHHHHCCCEECCCCEEEEEEHHCCCCCCC
ACATPVTQGMIVRTKSDKAIKAQQSVMEFLLINHPLDCPICDQGGECQLQDLAVGYGGDS
CCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCC
SRYGEEKRVVAHKDVGPLISMEEMTRCIHCTRCVRFGQEIAGVMELGMVNRGEHSEITTV
CCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IGDTVDSELSGNMIDLCPVGALTSKPFRYSARTWELSRRKSVSPHDSTGANLIVQVKNHK
HCCCCCHHHCCCEEEECCCCCCCCCCCCCCCCCEEHHHHCCCCCCCCCCCEEEEEEECCE
VMRVVPFENEDVNECWIADRDRFSYEALNSPDRLTRPMLKQGGEWKEVDWQTALEYVANG
EEEEECCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
LRCVKTEHGAQSIGALVSPHSTVEELFLAGALMRGLGSDNIDHRLRHAEFGKAEGVRWLG
CEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHH
TSIASLSTLQSVLVVGSNLRKDHPLFAQRIRQAARHGCAVSAINSVANDWAIPNVRTKLA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCC
PAAGWSTALAEVAAAIAAEKGVAAPVQGAATSEEARAIAAALLTGERKAILLGNGAAHHA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHH
QASSLLALAQWIGAQTGATVGYLTEAANTVGAQFVGAQPQEGGLNAAQMLDGRLKAALLL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEE
NVEPEHDSALGAAAAQALAQTDMVVTLSPFKTNLEFSDVLLPIAPFSETSGSFVNAEGRL
EECCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHEEEECCCCCCCCCCEECCCCHH
QSFHAVVKPAGEARPAWKVLRVLGNLLGLEGMDYETSQDVLVRATGKPAGECTQLPAERL
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHCCCHHHH
SNATSAEPKLGGECAEPVVAAIYQLDSLVRRAPSLQLTADARAAREGVAA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]