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The map label for this gene is hrcA

Identifier: 222110061

GI number: 222110061

Start: 874959

End: 875963

Strand: Direct

Name: hrcA

Synonym: Dtpsy_0847

Alternate gene names: 222110061

Gene position: 874959-875963 (Clockwise)

Preceding gene: 222110060

Following gene: 222110062

Centisome position: 23.05

GC content: 62.59

Gene sequence:

>1005_bases
ATGCTTGATGACCGCTCCAAGTTGTTACTCAAGGCCTTGGTGGAACGCTACATAGCCGAGGGGCAGCCGGTCGGCTCCAG
AACCTTGTCGCGGGCATCAGGGCTTGAATTGTCGCCCGCCACCATACGCAATGTGATGGCAGACCTGGAGGACCTGGGGC
TTATTGCCAGCCCCCACACCTCCGCGGGCCGTGTGCCCACCGCCAAGGGCTATCGCCTGTTCGTCGACACCATGCTCACC
GTGCAGCAGGAGCAGTTGCCGACAGTCCAGCTCATGCCCGAGCAGCCGCAGAAGGTGATCGCCAACGCCGCCCACCTGTT
GTCGAGCCTGTCGCAGTTCGTGGGGGTGGTGATGGCGCCGCGGCGCGCCTCGGTGTTTCGCCACATCGAATTCCTGCGGC
TGTCCGAGAAGCGTTTTTTGGTGATCATCGTCTCGCCCGACGGTGATGTGCAGAACCGCGTGATCTTTACCGAGGCCGAT
TACTCCCAGTCGCAACTGGTGGAGGCCGCCAACTTCCTCAACGCCAACTACGCGGGCCTCACCATGGAGCAGGTGCGCGA
GCGCCTGAAGCTGGAGGTGGACAAGCTGCGCGGAGAAATCGCGGCGCTGATGCAGGCCGCGGTGAGCGTGGACTCGGAGG
CCATGTCGGGGTCGCAGGACGAGGTGGTGTTCTCGGGCGAGCGCAACCTGCTGTCTGTGAGCGATTTTTCCAGCGACATG
AGCCACTTGCGCCGTGCGTTCGACCTGTTCGAACAAAAGACGCAGATCCTGCGCCTGCTGGACATTTCCAGCCGGGCAGA
AGGGGTGCGCATCTTCATTGGCGGAGAGAGCCAGGTGGTGCCATTTGAAGAGCTGTCCGTGGTGAGTGCACCCTATGAGG
TCGACGGTCAGGTGGTGGGCACCCTGGGCGTGATCGGCCCCACGCGCATGCCCTATGACCGCATGATCCAGATCGTGGAC
ATCACCTCCAAGCTGGTCTCCAACGCCCTGAGCCACCGAAAGTAG

Upstream 100 bases:

>100_bases
GGCGGACATGCTGGGCGTCACCGTTGCTTGCCTGCGAGACTGCATCCACCGGCATGAGCGTCGGGGCCGGTGGGCGGGGT
TACCAACGTAAAATGATTCA

Downstream 100 bases:

>100_bases
CCCCTACAATACGCGCCGCTGCGCCGCCTACGAGGCAGGGCAGCGCACCCCTTGGGGCGTTAGCTCAGTTGGTTAGAGCA
GAGGACTCATAATCCTTTGG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MLDDRSKLLLKALVERYIAEGQPVGSRTLSRASGLELSPATIRNVMADLEDLGLIASPHTSAGRVPTAKGYRLFVDTMLT
VQQEQLPTVQLMPEQPQKVIANAAHLLSSLSQFVGVVMAPRRASVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEAD
YSQSQLVEAANFLNANYAGLTMEQVRERLKLEVDKLRGEIAALMQAAVSVDSEAMSGSQDEVVFSGERNLLSVSDFSSDM
SHLRRAFDLFEQKTQILRLLDISSRAEGVRIFIGGESQVVPFEELSVVSAPYEVDGQVVGTLGVIGPTRMPYDRMIQIVD
ITSKLVSNALSHRK

Sequences:

>Translated_334_residues
MLDDRSKLLLKALVERYIAEGQPVGSRTLSRASGLELSPATIRNVMADLEDLGLIASPHTSAGRVPTAKGYRLFVDTMLT
VQQEQLPTVQLMPEQPQKVIANAAHLLSSLSQFVGVVMAPRRASVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEAD
YSQSQLVEAANFLNANYAGLTMEQVRERLKLEVDKLRGEIAALMQAAVSVDSEAMSGSQDEVVFSGERNLLSVSDFSSDM
SHLRRAFDLFEQKTQILRLLDISSRAEGVRIFIGGESQVVPFEELSVVSAPYEVDGQVVGTLGVIGPTRMPYDRMIQIVD
ITSKLVSNALSHRK
>Mature_334_residues
MLDDRSKLLLKALVERYIAEGQPVGSRTLSRASGLELSPATIRNVMADLEDLGLIASPHTSAGRVPTAKGYRLFVDTMLT
VQQEQLPTVQLMPEQPQKVIANAAHLLSSLSQFVGVVMAPRRASVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEAD
YSQSQLVEAANFLNANYAGLTMEQVRERLKLEVDKLRGEIAALMQAAVSVDSEAMSGSQDEVVFSGERNLLSVSDFSSDM
SHLRRAFDLFEQKTQILRLLDISSRAEGVRIFIGGESQVVPFEELSVVSAPYEVDGQVVGTLGVIGPTRMPYDRMIQIVD
ITSKLVSNALSHRK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_ACIET (B9MEI9)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002552325.1
- GeneID:   7383542
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_0847
- ProtClustDB:   PRK00082
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF03444 DUF293; PF01628 HrcA

EC number: NA

Molecular weight: Translated: 36875; Mature: 36875

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDDRSKLLLKALVERYIAEGQPVGSRTLSRASGLELSPATIRNVMADLEDLGLIASPHT
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRVPTAKGYRLFVDTMLTVQQEQLPTVQLMPEQPQKVIANAAHLLSSLSQFVGVVMAP
CCCCCCCCCCCEEHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RRASVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEADYSQSQLVEAANFLNANYAGL
HHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
TMEQVRERLKLEVDKLRGEIAALMQAAVSVDSEAMSGSQDEVVFSGERNLLSVSDFSSDM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECCCCCEEEHHHHHHHH
SHLRRAFDLFEQKTQILRLLDISSRAEGVRIFIGGESQVVPFEELSVVSAPYEVDGQVVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEE
TLGVIGPTRMPYDRMIQIVDITSKLVSNALSHRK
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDDRSKLLLKALVERYIAEGQPVGSRTLSRASGLELSPATIRNVMADLEDLGLIASPHT
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCEEECCCC
SAGRVPTAKGYRLFVDTMLTVQQEQLPTVQLMPEQPQKVIANAAHLLSSLSQFVGVVMAP
CCCCCCCCCCCEEHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
RRASVFRHIEFLRLSEKRFLVIIVSPDGDVQNRVIFTEADYSQSQLVEAANFLNANYAGL
HHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCC
TMEQVRERLKLEVDKLRGEIAALMQAAVSVDSEAMSGSQDEVVFSGERNLLSVSDFSSDM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEECCCCCEEEHHHHHHHH
SHLRRAFDLFEQKTQILRLLDISSRAEGVRIFIGGESQVVPFEELSVVSAPYEVDGQVVG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEE
TLGVIGPTRMPYDRMIQIVDITSKLVSNALSHRK
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA