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The map label for this gene is ybhO [H]

Identifier: 222110022

GI number: 222110022

Start: 839018

End: 840247

Strand: Direct

Name: ybhO [H]

Synonym: Dtpsy_0807

Alternate gene names: 222110022

Gene position: 839018-840247 (Clockwise)

Preceding gene: 222110021

Following gene: 222110023

Centisome position: 22.1

GC content: 72.36

Gene sequence:

>1230_bases
ATGGTCGCCCCCACGCGCGCGCACGCTACCGGCCGAGACCACCAGATCCAGCTGCTGCAGGGCACGCAGGAGTTGTTCCC
GGCGCTGATCGCCGAGATGGATGCGGCGCTGTCCGATATCCAGTTCGAGACCTACATCTTTGACTGCACTGGCGCGGGCG
CCGACGTGGCCGAGGCGCTGATGCGCGCAGCCCGGCGCGGCGTGCGCGTGCACCTGGCGCTGGACGGCGTGGGCACGGGG
CGGCTGCCCGAGCCTTGGCGCACCCGCATGGTGCAGGCCGGCGTGCACGTGCAGGTGTATTCGCCGCTCGGCCCGCTGGG
CCTGCTGCTGCCGATGCGCTGGCGCCGGCTGCACCGCAAGCTGTGCGTGGTGGATGGCTGCGTGCTGTACTGCGGCGGCA
TCAACGTGCTGGACGACTTCCACGACCCCAACCACGGCGCGCTCACCGCGCCGCGCTTTGACTTTGCCGTGCGCGCCGAG
GGCAGCCTGGTGCAGCAGGCCAGCGAGACCATGGAGCAACTGTGGTGGCGCATGCGCGCGGTGCGCGACGTACGCCAGCG
CCGCCTGTCGCTGGCCCTGGCCGACCTGCGCGCCGCCAGCGCCGCACGCCTGGCGGCGCGGCGCGCCGAGAGCCGTGCGC
GGGGCATGCGCGCCGAGCTGGTGCTGCGCGACAACGTGCGCAACCGTGCACGCATCGAGCGCGCCTACCTGCGCGCCATT
GCCCGCGCGCGGCATGAGGTCATCATCGCCAACGCCTACTTCGTGCCCGGTGGCAAGCTGCGCCGCGCGCTGGTGCTGGC
GGCGCGGCGCGGCGTGCGCGTACAGCTGCTGCTGCAGGGGCGGTACGAATACTTCATGCAATACCACGCAGCGCGGCCGG
TGTACGGCACGCTGCTGGCGGCGGGCGTGGAGATTCATGAATACGCGCCCAGCTTCCTGCACGCCAAGGTGGCGGTGATC
GACGCGGACAGCCGCCGCGCCTGGGCCACGGTGGGCTCGTCCAACCTGGACCCGCTGTCGCTGCTGCTGGCGCGCGAGGC
CAATGTGATCGTGCGCGACGCCCCCTTTGCCCAGGACCTGCGCAAGCGGCTGCGCCACGCCATGGCCCACGAGGGCCGCC
AGCTTGACCCGCAGCGCTACGCCGAACGCCCCTGGCGCGAGCGCGCGCTGGACCGCATCGCCTTCGGCATCATGCGCGCG
GCCCTGTGGGTGACGGGCAACCGCTACTGA

Upstream 100 bases:

>100_bases
CGGGGCCTCACCCCGCTGGGGCTGCAGGTGCCGCGTGGGCGGATCTGGTGGCGCATGTCGGACCATTTGCCGCTGATCGC
AGAGTTCAAGCTCTGACTCC

Downstream 100 bases:

>100_bases
ATGCCGCGCCCTGCCGGTGGGATAATATTGCTATTGTTTGGATAGCTGCTGGCGCTTGCCCCATAAGCGCTAGAGGCATA
AAAGGCTTATAAAGCCTGGA

Product: phospholipase d/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MVAPTRAHATGRDHQIQLLQGTQELFPALIAEMDAALSDIQFETYIFDCTGAGADVAEALMRAARRGVRVHLALDGVGTG
RLPEPWRTRMVQAGVHVQVYSPLGPLGLLLPMRWRRLHRKLCVVDGCVLYCGGINVLDDFHDPNHGALTAPRFDFAVRAE
GSLVQQASETMEQLWWRMRAVRDVRQRRLSLALADLRAASAARLAARRAESRARGMRAELVLRDNVRNRARIERAYLRAI
ARARHEVIIANAYFVPGGKLRRALVLAARRGVRVQLLLQGRYEYFMQYHAARPVYGTLLAAGVEIHEYAPSFLHAKVAVI
DADSRRAWATVGSSNLDPLSLLLAREANVIVRDAPFAQDLRKRLRHAMAHEGRQLDPQRYAERPWRERALDRIAFGIMRA
ALWVTGNRY

Sequences:

>Translated_409_residues
MVAPTRAHATGRDHQIQLLQGTQELFPALIAEMDAALSDIQFETYIFDCTGAGADVAEALMRAARRGVRVHLALDGVGTG
RLPEPWRTRMVQAGVHVQVYSPLGPLGLLLPMRWRRLHRKLCVVDGCVLYCGGINVLDDFHDPNHGALTAPRFDFAVRAE
GSLVQQASETMEQLWWRMRAVRDVRQRRLSLALADLRAASAARLAARRAESRARGMRAELVLRDNVRNRARIERAYLRAI
ARARHEVIIANAYFVPGGKLRRALVLAARRGVRVQLLLQGRYEYFMQYHAARPVYGTLLAAGVEIHEYAPSFLHAKVAVI
DADSRRAWATVGSSNLDPLSLLLAREANVIVRDAPFAQDLRKRLRHAMAHEGRQLDPQRYAERPWRERALDRIAFGIMRA
ALWVTGNRY
>Mature_409_residues
MVAPTRAHATGRDHQIQLLQGTQELFPALIAEMDAALSDIQFETYIFDCTGAGADVAEALMRAARRGVRVHLALDGVGTG
RLPEPWRTRMVQAGVHVQVYSPLGPLGLLLPMRWRRLHRKLCVVDGCVLYCGGINVLDDFHDPNHGALTAPRFDFAVRAE
GSLVQQASETMEQLWWRMRAVRDVRQRRLSLALADLRAASAARLAARRAESRARGMRAELVLRDNVRNRARIERAYLRAI
ARARHEVIIANAYFVPGGKLRRALVLAARRGVRVQLLLQGRYEYFMQYHAARPVYGTLLAAGVEIHEYAPSFLHAKVAVI
DADSRRAWATVGSSNLDPLSLLLAREANVIVRDAPFAQDLRKRLRHAMAHEGRQLDPQRYAERPWRERALDRIAFGIMRA
ALWVTGNRY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=393, Percent_Identity=36.8956743002545, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1787502, Length=385, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081826, Length=414, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 46089; Mature: 46089

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPTRAHATGRDHQIQLLQGTQELFPALIAEMDAALSDIQFETYIFDCTGAGADVAEAL
CCCCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHH
MRAARRGVRVHLALDGVGTGRLPEPWRTRMVQAGVHVQVYSPLGPLGLLLPMRWRRLHRK
HHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
LCVVDGCVLYCGGINVLDDFHDPNHGALTAPRFDFAVRAEGSLVQQASETMEQLWWRMRA
HHHHCCCEEEECCCHHHHCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
VRDVRQRRLSLALADLRAASAARLAARRAESRARGMRAELVLRDNVRNRARIERAYLRAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
ARARHEVIIANAYFVPGGKLRRALVLAARRGVRVQLLLQGRYEYFMQYHAARPVYGTLLA
HHHHCEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHH
AGVEIHEYAPSFLHAKVAVIDADSRRAWATVGSSNLDPLSLLLAREANVIVRDAPFAQDL
HCCHHHHHCCHHHEEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCEEEECCCHHHHH
RKRLRHAMAHEGRQLDPQRYAERPWRERALDRIAFGIMRAALWVTGNRY
HHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVAPTRAHATGRDHQIQLLQGTQELFPALIAEMDAALSDIQFETYIFDCTGAGADVAEAL
CCCCCCCCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHH
MRAARRGVRVHLALDGVGTGRLPEPWRTRMVQAGVHVQVYSPLGPLGLLLPMRWRRLHRK
HHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHH
LCVVDGCVLYCGGINVLDDFHDPNHGALTAPRFDFAVRAEGSLVQQASETMEQLWWRMRA
HHHHCCCEEEECCCHHHHCCCCCCCCCEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
VRDVRQRRLSLALADLRAASAARLAARRAESRARGMRAELVLRDNVRNRARIERAYLRAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
ARARHEVIIANAYFVPGGKLRRALVLAARRGVRVQLLLQGRYEYFMQYHAARPVYGTLLA
HHHHCEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHH
AGVEIHEYAPSFLHAKVAVIDADSRRAWATVGSSNLDPLSLLLAREANVIVRDAPFAQDL
HCCHHHHHCCHHHEEEEEEEECCCCCEEEECCCCCCCHHHHHHHCCCCEEEECCCHHHHH
RKRLRHAMAHEGRQLDPQRYAERPWRERALDRIAFGIMRAALWVTGNRY
HHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]