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The map label for this gene is aspS [H]

Identifier: 222110018

GI number: 222110018

Start: 835057

End: 836868

Strand: Direct

Name: aspS [H]

Synonym: Dtpsy_0803

Alternate gene names: 222110018

Gene position: 835057-836868 (Clockwise)

Preceding gene: 222110017

Following gene: 222110019

Centisome position: 22.0

GC content: 64.13

Gene sequence:

>1812_bases
ATGGCCATGCGCTCCCACTACTGCGGTCTTGTGACCGAAGCCCTCCTGGGCCAAACCGTCACCCTGTCGGGCTGGGTGAA
CCGTCGCCGCGACCATGGCGGCGTGATCTTCATCGACCTGCGCGACCGCGAAGGCTATGTGCAGGTGGTTTGCGACCCTG
ACCGTCCCGAGATGTTCAAGGTGGCCGAGGACGTCCGTAACGAGTTCTGCGTGCAGGTCAAGGGTTTGGTGCGCGCGCGC
CCCGAAGGCACGACCAACGACAGCCTCAAGAGCGGCAAGATCGAGGTGCTGTGCCAGGAGCTCAACGTCCTGAACCCGTC
CGTGACGCCGCCCTTCCAGATGGACGACGACAACCTGTCGGAAACCACGCGCCTCACGCACCGCGTGATGGACCTGCGCC
GCCCGTACATGCAGCGCAACATGATGCTGCGCTACAAGACGGCCATCCAGGTGCGCAACTTCCTGGACAAGGAAGGCTTC
ATCGACATCGAAACGCCCATGCTGGGCAAGAGCACGCCCGAGGGGGCGCGCGACTACCTCGTGCCCAGCCGCGTGCACGA
CGGCCAGTTCTTCGCGCTGCCGCAGTCGCCCCAGCTCTACAAGCAGATGCTGATGGTGGCCGGCTACGACCGCTACTACC
AGATCACCAAGTGCTTCCGCGACGAGGATCTGCGCGCCGACCGCCAGCCCGAGTTCACGCAGATCGACTGCGAGACCTCG
TTCCTGAACGAGGAAGAGATCCGCGCCATCTTCCAGCGCATGATCAAGGAAGTGTTCCAGCAGCAACTGGGCGTGGACCT
GGGTGAATTCCCCACCATGACCTACCAGGAAGCAGCGCACCGCTTCGGCTCCGACAAGCCTGACCTGCGCGTGAAGCTCG
AATTCACCGAGCTGACCGATGTCATGAAGGACGTGGACTTCAAGGTCTTCTCCGGCGCCGCCAACATGAAGGGCGGCCGT
GTGGTGGCCCTGCGCGTGCCCGGTGGCGCCCGTGAAGAGGGCGGCCTGTCGCGCGGCGAGATCGACGGCTATACCGAGTT
CGTGAAGATCTACGGCGCCAAGGGTCTGGCTTACATCAAGGTCAACGACAAGGCCAAGGGCCGTGACGGCCTGCAGTCGC
CCATCGTCAAGAACATCCATGACGCCGCACTGGCCGAAGTGCTCCAGCGCACGGGCGCACAGGACGGCGACCTGCTGTTC
TTTGGCGCCGACAAGGAAAAGATCGTCAACGACGCCATCGGCGCACTGCGCCTGAAGGTCGGCCACAGCGAATTCGGCAA
GAAGAATGGTCTGTTCGAGAACCGCTGGGCGCCGCTGTGGGTGGTGGACTTTCCCATGTTCGAGCATGACGAGGAAGAAG
ACCGCTGGGTGGCCGTGCACCACCCCTTCACGTCGCCGAAGGACGGCCATGAGAACCTCATGGACACCGATCCCGGCAAG
TGCATTGCCAAGGCCTACGACATGGTGCTGAACGGCTGGGAACTGGGCGGCGGCTCGGTGCGTATCCACCGCGCTGATGT
GCAGGCCAAGGTGTTTGCGGCGCTCAATATCGGCCCGGAAGACCAGCGCGCGAAGTTCGGCTACCTGCTGGACGCGTTGC
AGTACGGCGCGCCTCCACACGGCGGCCTGGCCTTCGGCCTGGACCGCCTGATCACGCTGATGACGGGAGCCGAGTCCATC
CGCGACGTGATCGCCTTCCCCAAGACCCAGCGCGCCCAGGATCTGCTGACCCAGGCCCCTTCGCCTGTGGACGAAAAGCA
GCTGCGCGAACTGCACATCCGCCTGCGCAACCCGCTGCCTGCAGCCCACTGA

Upstream 100 bases:

>100_bases
CTCCATAAGAAAACCGTCGTCGCCCGCCCGTGCCTGTGCGCCGAGTGGGTGGAAAGAACAACCATCGTCGCGTCCCACGA
GGACGCAGGAAGACTGATCC

Downstream 100 bases:

>100_bases
GGGGCGCGCGGGCTCCGACACCTAAGCGGCAGGCGCGTTCACGTGCCTGCCGTTTTTGTTTGCCATAACGTGTCCACAAG
CTCTTGGAGGGAGACCATGC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MAMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFKVAEDVRNEFCVQVKGLVRAR
PEGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLSETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGF
IDIETPMLGKSTPEGARDYLVPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTDVMKDVDFKVFSGAANMKGGR
VVALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIKVNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLF
FGADKEKIVNDAIGALRLKVGHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGK
CIAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPHGGLAFGLDRLITLMTGAESI
RDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLPAAH

Sequences:

>Translated_603_residues
MAMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFKVAEDVRNEFCVQVKGLVRAR
PEGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLSETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGF
IDIETPMLGKSTPEGARDYLVPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETS
FLNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTDVMKDVDFKVFSGAANMKGGR
VVALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIKVNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLF
FGADKEKIVNDAIGALRLKVGHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGK
CIAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPHGGLAFGLDRLITLMTGAESI
RDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLPAAH
>Mature_602_residues
AMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFKVAEDVRNEFCVQVKGLVRARP
EGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLSETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGFI
DIETPMLGKSTPEGARDYLVPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETSF
LNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTDVMKDVDFKVFSGAANMKGGRV
VALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIKVNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLFF
GADKEKIVNDAIGALRLKVGHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGKC
IAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPHGGLAFGLDRLITLMTGAESIR
DVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLPAAH

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=612, Percent_Identity=37.9084967320261, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI45439306, Length=315, Percent_Identity=27.3015873015873, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI194272210, Length=254, Percent_Identity=25.9842519685039, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI5031815, Length=254, Percent_Identity=25.9842519685039, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1788173, Length=594, Percent_Identity=57.7441077441077, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=273, Percent_Identity=24.9084249084249, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789256, Length=292, Percent_Identity=25.3424657534247, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787161, Length=236, Percent_Identity=29.2372881355932, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32566633, Length=623, Percent_Identity=32.2632423756019, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI17551876, Length=289, Percent_Identity=26.643598615917, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994340, Length=270, Percent_Identity=23.7037037037037, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535927, Length=270, Percent_Identity=23.7037037037037, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535925, Length=252, Percent_Identity=25, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325153, Length=639, Percent_Identity=33.8028169014084, Blast_Score=295, Evalue=1e-80,
Organism=Saccharomyces cerevisiae, GI6323011, Length=251, Percent_Identity=27.0916334661355, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321807, Length=252, Percent_Identity=27.3809523809524, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320242, Length=271, Percent_Identity=25.0922509225092, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584738, Length=609, Percent_Identity=35.303776683087, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI17136276, Length=239, Percent_Identity=30.1255230125523, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640849, Length=249, Percent_Identity=26.5060240963855, Blast_Score=77, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640851, Length=249, Percent_Identity=26.5060240963855, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 68113; Mature: 67981

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFK
CCCCHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHH
VAEDVRNEFCVQVKGLVRARPEGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGFIDIETPMLGKSTPEGARDYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHCC
VPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTD
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHH
VMKDVDFKVFSGAANMKGGRVVALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIK
HHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLFFGADKEKIVNDAIGALRLKV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHEEEEE
GHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGK
CCHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
CIAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPH
HHHHHHHHHHCCEEECCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRLITLMTGAESIRDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLP
CCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
AAH
CCC
>Mature Secondary Structure 
AMRSHYCGLVTEALLGQTVTLSGWVNRRRDHGGVIFIDLRDREGYVQVVCDPDRPEMFK
CCCHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHH
VAEDVRNEFCVQVKGLVRARPEGTTNDSLKSGKIEVLCQELNVLNPSVTPPFQMDDDNLS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ETTRLTHRVMDLRRPYMQRNMMLRYKTAIQVRNFLDKEGFIDIETPMLGKSTPEGARDYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHCC
VPSRVHDGQFFALPQSPQLYKQMLMVAGYDRYYQITKCFRDEDLRADRQPEFTQIDCETS
CCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEECCHH
FLNEEEIRAIFQRMIKEVFQQQLGVDLGEFPTMTYQEAAHRFGSDKPDLRVKLEFTELTD
HCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHH
VMKDVDFKVFSGAANMKGGRVVALRVPGGAREEGGLSRGEIDGYTEFVKIYGAKGLAYIK
HHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEE
VNDKAKGRDGLQSPIVKNIHDAALAEVLQRTGAQDGDLLFFGADKEKIVNDAIGALRLKV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHEEEEE
GHSEFGKKNGLFENRWAPLWVVDFPMFEHDEEEDRWVAVHHPFTSPKDGHENLMDTDPGK
CCHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHH
CIAKAYDMVLNGWELGGGSVRIHRADVQAKVFAALNIGPEDQRAKFGYLLDALQYGAPPH
HHHHHHHHHHCCEEECCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCC
GGLAFGLDRLITLMTGAESIRDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRNPLP
CCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
AAH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA