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The map label for this gene is ushA [C]

Identifier: 222109886

GI number: 222109886

Start: 695584

End: 697497

Strand: Direct

Name: ushA [C]

Synonym: Dtpsy_0670

Alternate gene names: 222109886

Gene position: 695584-697497 (Clockwise)

Preceding gene: 222109885

Following gene: 222109887

Centisome position: 18.32

GC content: 67.29

Gene sequence:

>1914_bases
ATGGGTTCGTGGATGCAATGGGCCAACAAGCCCTACGGGCGGCGGGTGCGGATGGGCGCGGTGGCGCTGGCGGCGTGTGG
CGTGCTGGCGGCATGCGGTGGCAACGATGACGACGAGGCCCAGCCGCTGGAACTGACCGTCCTGCACATCAACGACCACC
ACTCCACGCTGGACGCCAAGTCCAAGACGCTGAAGCTGTCCACGGGCGGCGCCGCGCCTGTGGACGTGGCCGTCGAAGCC
GGCGGCTTTGCGCGCGTCACCGCGGCCTTCGACAGCCTGGCCAAGGCCGCGGGCGCCAACGTGCTCAAGCTGCATGCGGG
CGACGCGCTCACCGGCACGCTGTACTTCAACCGCGCGGGCGCGGACGGCGAGGCCGATGCCGCGCTGATGAACACCGTGT
GCTTCGACGCCTTCACGCTGGGCAACCACGAGTTCGACAAGGGTGACGCGGGCCTCAAGGGATTCCTGGACCTGCTCAAG
AAGGGGTCCTGCAAGACGGCGGTGCTCAGCGCCAACGTGAAGTTCGGTGCCGGCTCGGCGCTCAACGCCACCAAGGCACC
CGGTTACGTGCAGCCTTCCACCGTGGTGGAGCGCAGCGGCCAGAAGATCGGCATCGTCGGCCTGACGATTGCGGGCAAGA
CCAAGGCCTCGTCCAGCCCCGACGCGGACACCACCTTCGAGGACGAAGTCACGGCGGCGCAGCGTGAGATCGACAAGCTG
CGCGCCCAGAGCATCAACAAGATCATCGTCATGAGCCACGTGGGCTATGGCTACGACAAGGAAATCGCCGCCAAGCTCAG
CGGCGTGGACGTGATCGTGGGCGGCGATTCGCACACGCTGCTGGGCCCCGATGCGCTCAAGACCACGGGCGTGGGCACGC
CCAGTGGCGCCTATCCCACGCGCGTGACCGACAAGGACGGCAAGAACGTCTGCGTGGTGCAGGCCTGGGAATACGCGCAG
GTGGTGGGCGAGTTGAACGTGCGTTTTGACGGCAAGGGCGAGGTCACGCAGTGCAGTGGCACGCCGCATGTGCTGATCGG
TAGCGACTTCACCATCAACAAATTGCCCCCGACCGATGCCGAAAAGAAGGCCATCGATGCCGACGTGGCGGCCAAGGGCT
TTCTGCGCGTGACGCAGCCAGCCGCCGCCGCCACCACGGCGCTGCAGCCGTTCAAGGACCGCGTGGCCGTTTTCAACAAG
ACCAACGTGGCGGTGGTGCCGAAGGAGTTGTGCTTCCGCCGCGTGCCGGGCAATCCCGGCTCGGGCGGCTCCAGCCCCAC
GTGCAACGCCGAGGGCAGCGTGCATCTGCGCGGTGGCGACATCCAGCAGCTGGTGGCGCAGGCCTACGTGGACGAGGGCA
ATGCCAAGTACGGCGGCGCCGACATCTCGCTGCAAAGCGGCGGTGGTGTGCGCATTGCGCTGGACGGCACGGTGACAGCA
GCGCAGGTGATCCAGGTGCTGCCCTTCGGCAACATGCTGTTCCGTCTGGACGTGACCGGCGCGGAGGTCAAATCCATGCT
CGAAGACGGTCTGGAGGCCGTGTTCAAGGCGGGCGGATCGACCGGGCCCTATCCCTATACCGGCGGCCTGCGCTTCGACG
TGAACGCCTCGGCCGCCTTCGGCCAGCGCGCCTCCGGTCTCGAAGTGCGCAACGCCGCCACCGGCACCTGGGGGCCGATC
GATCCGGCCAAGACCTACAGGCTCTTCGTGTTGAGTTTCAACGCCACGGGCGGCGACGGCTACAAGACGCTGGCGGCCGT
GCCCGCGGCGCGGCGCCTGGATATCGGCGTGCTGGATGCCGATGTGTTCTTCAGCTACATCGACAAGCAGCCGCGTGACG
CCGCCACCGGCCTGCCCATGCTGAACCGCCTGTCGCACGAGCTCTACAGCACCAAGAGCTTCGCGGGGCAGTGA

Upstream 100 bases:

>100_bases
CGCGCCCTGTTCTACGGGCGCGCGTGTGGGGCTTTCACGGCGCTGTCATCCTTGCTTCCCACCATCTCCACTCTGTAACG
ATTCAACAGGGAGCGAGAAC

Downstream 100 bases:

>100_bases
CGGGACCAGTGAAGTGAACGGCGGGAATGCGCGGGCATACTGACGGTTTCCCGTCAACGAACCCCAGGAGTACCGCGCAT
GACCGCCTTCACCCTCACCA

Product: 5'-nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MGSWMQWANKPYGRRVRMGAVALAACGVLAACGGNDDDEAQPLELTVLHINDHHSTLDAKSKTLKLSTGGAAPVDVAVEA
GGFARVTAAFDSLAKAAGANVLKLHAGDALTGTLYFNRAGADGEADAALMNTVCFDAFTLGNHEFDKGDAGLKGFLDLLK
KGSCKTAVLSANVKFGAGSALNATKAPGYVQPSTVVERSGQKIGIVGLTIAGKTKASSSPDADTTFEDEVTAAQREIDKL
RAQSINKIIVMSHVGYGYDKEIAAKLSGVDVIVGGDSHTLLGPDALKTTGVGTPSGAYPTRVTDKDGKNVCVVQAWEYAQ
VVGELNVRFDGKGEVTQCSGTPHVLIGSDFTINKLPPTDAEKKAIDADVAAKGFLRVTQPAAAATTALQPFKDRVAVFNK
TNVAVVPKELCFRRVPGNPGSGGSSPTCNAEGSVHLRGGDIQQLVAQAYVDEGNAKYGGADISLQSGGGVRIALDGTVTA
AQVIQVLPFGNMLFRLDVTGAEVKSMLEDGLEAVFKAGGSTGPYPYTGGLRFDVNASAAFGQRASGLEVRNAATGTWGPI
DPAKTYRLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIDKQPRDAATGLPMLNRLSHELYSTKSFAGQ

Sequences:

>Translated_637_residues
MGSWMQWANKPYGRRVRMGAVALAACGVLAACGGNDDDEAQPLELTVLHINDHHSTLDAKSKTLKLSTGGAAPVDVAVEA
GGFARVTAAFDSLAKAAGANVLKLHAGDALTGTLYFNRAGADGEADAALMNTVCFDAFTLGNHEFDKGDAGLKGFLDLLK
KGSCKTAVLSANVKFGAGSALNATKAPGYVQPSTVVERSGQKIGIVGLTIAGKTKASSSPDADTTFEDEVTAAQREIDKL
RAQSINKIIVMSHVGYGYDKEIAAKLSGVDVIVGGDSHTLLGPDALKTTGVGTPSGAYPTRVTDKDGKNVCVVQAWEYAQ
VVGELNVRFDGKGEVTQCSGTPHVLIGSDFTINKLPPTDAEKKAIDADVAAKGFLRVTQPAAAATTALQPFKDRVAVFNK
TNVAVVPKELCFRRVPGNPGSGGSSPTCNAEGSVHLRGGDIQQLVAQAYVDEGNAKYGGADISLQSGGGVRIALDGTVTA
AQVIQVLPFGNMLFRLDVTGAEVKSMLEDGLEAVFKAGGSTGPYPYTGGLRFDVNASAAFGQRASGLEVRNAATGTWGPI
DPAKTYRLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIDKQPRDAATGLPMLNRLSHELYSTKSFAGQ
>Mature_636_residues
GSWMQWANKPYGRRVRMGAVALAACGVLAACGGNDDDEAQPLELTVLHINDHHSTLDAKSKTLKLSTGGAAPVDVAVEAG
GFARVTAAFDSLAKAAGANVLKLHAGDALTGTLYFNRAGADGEADAALMNTVCFDAFTLGNHEFDKGDAGLKGFLDLLKK
GSCKTAVLSANVKFGAGSALNATKAPGYVQPSTVVERSGQKIGIVGLTIAGKTKASSSPDADTTFEDEVTAAQREIDKLR
AQSINKIIVMSHVGYGYDKEIAAKLSGVDVIVGGDSHTLLGPDALKTTGVGTPSGAYPTRVTDKDGKNVCVVQAWEYAQV
VGELNVRFDGKGEVTQCSGTPHVLIGSDFTINKLPPTDAEKKAIDADVAAKGFLRVTQPAAAATTALQPFKDRVAVFNKT
NVAVVPKELCFRRVPGNPGSGGSSPTCNAEGSVHLRGGDIQQLVAQAYVDEGNAKYGGADISLQSGGGVRIALDGTVTAA
QVIQVLPFGNMLFRLDVTGAEVKSMLEDGLEAVFKAGGSTGPYPYTGGLRFDVNASAAFGQRASGLEVRNAATGTWGPID
PAKTYRLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIDKQPRDAATGLPMLNRLSHELYSTKSFAGQ

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=578, Percent_Identity=31.3148788927336, Blast_Score=198, Evalue=1e-50,
Organism=Escherichia coli, GI1786687, Length=627, Percent_Identity=27.1132376395534, Blast_Score=132, Evalue=5e-32,
Organism=Drosophila melanogaster, GI19922446, Length=578, Percent_Identity=29.9307958477509, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24654424, Length=578, Percent_Identity=29.9307958477509, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24641187, Length=587, Percent_Identity=29.3015332197615, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI19922444, Length=563, Percent_Identity=29.3072824156306, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI28573524, Length=556, Percent_Identity=29.4964028776978, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI221329836, Length=591, Percent_Identity=27.2419627749577, Blast_Score=174, Evalue=2e-43,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 66228; Mature: 66097

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00785 5_NUCLEOTIDASE_1 ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSWMQWANKPYGRRVRMGAVALAACGVLAACGGNDDDEAQPLELTVLHINDHHSTLDAK
CCCHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCC
SKTLKLSTGGAAPVDVAVEAGGFARVTAAFDSLAKAAGANVLKLHAGDALTGTLYFNRAG
CCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECC
ADGEADAALMNTVCFDAFTLGNHEFDKGDAGLKGFLDLLKKGSCKTAVLSANVKFGAGSA
CCCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEECCCCC
LNATKAPGYVQPSTVVERSGQKIGIVGLTIAGKTKASSSPDADTTFEDEVTAAQREIDKL
CCCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RAQSINKIIVMSHVGYGYDKEIAAKLSGVDVIVGGDSHTLLGPDALKTTGVGTPSGAYPT
HHHCCCEEEEEEECCCCCCHHHHHHCCCEEEEECCCCCEEECCCHHHCCCCCCCCCCCCC
RVTDKDGKNVCVVQAWEYAQVVGELNVRFDGKGEVTQCSGTPHVLIGSDFTINKLPPTDA
EECCCCCCCEEEEECHHHHHHHHCEEEEECCCCCEEEECCCCEEEECCCEEECCCCCCCC
EKKAIDADVAAKGFLRVTQPAAAATTALQPFKDRVAVFNKTNVAVVPKELCFRRVPGNPG
HHHHCCHHHHCCCCEEECCCHHHHHHHHHHHHHHEEEEECCCEEEECHHHHHCCCCCCCC
SGGSSPTCNAEGSVHLRGGDIQQLVAQAYVDEGNAKYGGADISLQSGGGVRIALDGTVTA
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEECCEEEEEECCCCEEEEECCCHHH
AQVIQVLPFGNMLFRLDVTGAEVKSMLEDGLEAVFKAGGSTGPYPYTGGLRFDVNASAAF
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHC
GQRASGLEVRNAATGTWGPIDPAKTYRLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDA
CCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECH
DVFFSYIDKQPRDAATGLPMLNRLSHELYSTKSFAGQ
HHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure 
GSWMQWANKPYGRRVRMGAVALAACGVLAACGGNDDDEAQPLELTVLHINDHHSTLDAK
CCHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCC
SKTLKLSTGGAAPVDVAVEAGGFARVTAAFDSLAKAAGANVLKLHAGDALTGTLYFNRAG
CCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECC
ADGEADAALMNTVCFDAFTLGNHEFDKGDAGLKGFLDLLKKGSCKTAVLSANVKFGAGSA
CCCCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECEEECCCCC
LNATKAPGYVQPSTVVERSGQKIGIVGLTIAGKTKASSSPDADTTFEDEVTAAQREIDKL
CCCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RAQSINKIIVMSHVGYGYDKEIAAKLSGVDVIVGGDSHTLLGPDALKTTGVGTPSGAYPT
HHHCCCEEEEEEECCCCCCHHHHHHCCCEEEEECCCCCEEECCCHHHCCCCCCCCCCCCC
RVTDKDGKNVCVVQAWEYAQVVGELNVRFDGKGEVTQCSGTPHVLIGSDFTINKLPPTDA
EECCCCCCCEEEEECHHHHHHHHCEEEEECCCCCEEEECCCCEEEECCCEEECCCCCCCC
EKKAIDADVAAKGFLRVTQPAAAATTALQPFKDRVAVFNKTNVAVVPKELCFRRVPGNPG
HHHHCCHHHHCCCCEEECCCHHHHHHHHHHHHHHEEEEECCCEEEECHHHHHCCCCCCCC
SGGSSPTCNAEGSVHLRGGDIQQLVAQAYVDEGNAKYGGADISLQSGGGVRIALDGTVTA
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCEECCEEEEEECCCCEEEEECCCHHH
AQVIQVLPFGNMLFRLDVTGAEVKSMLEDGLEAVFKAGGSTGPYPYTGGLRFDVNASAAF
HHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHC
GQRASGLEVRNAATGTWGPIDPAKTYRLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDA
CCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEECH
DVFFSYIDKQPRDAATGLPMLNRLSHELYSTKSFAGQ
HHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]