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The map label for this gene is argB [H]

Identifier: 222109784

GI number: 222109784

Start: 587586

End: 588491

Strand: Direct

Name: argB [H]

Synonym: Dtpsy_0568

Alternate gene names: 222109784

Gene position: 587586-588491 (Clockwise)

Preceding gene: 222109783

Following gene: 222109785

Centisome position: 15.48

GC content: 60.93

Gene sequence:

>906_bases
ATGCCTCCTAATATTCAACCTGACCTCTTGGGCATTGCCCCCCGCGACAAGGCCGAAATCCTGGCCCAGGCGCTGCCGTA
CATCCGCAAGTTCCATGGCAAGACCATGGTCATCAAATATGGCGGCAACGCCATGACCGACCCGGCCCTGCAGGCCGACT
TTGCGGAAGACGTGGTGCTGCTCAAGCTGGTAGGCATGAACCCGGTGGTGGTGCACGGCGGAGGCCCGCAGATCGAGCAA
GCCCTGAACCGTCTGGGCAAGAAGGGCGAGTTCATTCAGGGCATGCGCGTGACCGATGCCGAAACCATGGAAGTCGTGGA
ATGGGTGCTGGCCGGCGAGGTGCAGCAGGACATCGTGGGCCTGATTCACCAGGCGGGCGGCAAGGCTGTGGGCCTCACGG
GGCGCGATGGCGGCATGATCCGCGCCAAGAAGCTCAAGATGGTGGACAACAAGGACCCGAGCGTCGAACATGACGTGGGG
CAGGTCGGTGACATCGTGGCGATCGACCCGAGCGTAGTCAAGGCGCTGCAGGACGATGCCTTCATTCCCGTCATCAGCCC
GATCGGGTTTGGCGAGGAAAACGAAAGCTACAACATCAACGCCGACGTGGTGGCGAGTAAATTAGCTACGGTGCTGCAGG
CGGAGAAACTGGTGCTGCTCACCAACACCCCCGGTGTGCTGGACAAGGAAGGCAAGCTGCTCACCGACCTGACGGCGCGC
GAAATTGATGCATTGTTCGCTGATGGCACCATCTCCGGCGGCATGCTGCCCAAGATCAGCGGGGCGTTGGATGCGGCAAA
GGCTGGCGTGAATGCCGTGCACATCATTGATGGCCGCGTACCGCATTCGATGTTGTTGGAAATTCTGACCGACCAGGCCT
ACGGCACCATGATCCGGAGTCACTAG

Upstream 100 bases:

>100_bases
GCGGCTTATCTAGCCATTGTCCGGTTTAAGGTGCCTGGCTGGTTGCGGCGTTGAGCGTTACGTCTTCTAGAATCCTGCGG
TTTTCCTGCAGACTTCGCCT

Downstream 100 bases:

>100_bases
GCTCTTTTCGGGCATGGCCCGGGTATATTGGAGTCAAAAATGGCTGCAGCGCTTGTCCAGCAAGCGTTAGCAGCTATTTT
TTTTGGAAGCGGATCCAAGG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPPNIQPDLLGIAPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVLLKLVGMNPVVVHGGGPQIEQ
ALNRLGKKGEFIQGMRVTDAETMEVVEWVLAGEVQQDIVGLIHQAGGKAVGLTGRDGGMIRAKKLKMVDNKDPSVEHDVG
QVGDIVAIDPSVVKALQDDAFIPVISPIGFGEENESYNINADVVASKLATVLQAEKLVLLTNTPGVLDKEGKLLTDLTAR
EIDALFADGTISGGMLPKISGALDAAKAGVNAVHIIDGRVPHSMLLEILTDQAYGTMIRSH

Sequences:

>Translated_301_residues
MPPNIQPDLLGIAPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVLLKLVGMNPVVVHGGGPQIEQ
ALNRLGKKGEFIQGMRVTDAETMEVVEWVLAGEVQQDIVGLIHQAGGKAVGLTGRDGGMIRAKKLKMVDNKDPSVEHDVG
QVGDIVAIDPSVVKALQDDAFIPVISPIGFGEENESYNINADVVASKLATVLQAEKLVLLTNTPGVLDKEGKLLTDLTAR
EIDALFADGTISGGMLPKISGALDAAKAGVNAVHIIDGRVPHSMLLEILTDQAYGTMIRSH
>Mature_300_residues
PPNIQPDLLGIAPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVLLKLVGMNPVVVHGGGPQIEQA
LNRLGKKGEFIQGMRVTDAETMEVVEWVLAGEVQQDIVGLIHQAGGKAVGLTGRDGGMIRAKKLKMVDNKDPSVEHDVGQ
VGDIVAIDPSVVKALQDDAFIPVISPIGFGEENESYNINADVVASKLATVLQAEKLVLLTNTPGVLDKEGKLLTDLTARE
IDALFADGTISGGMLPKISGALDAAKAGVNAVHIIDGRVPHSMLLEILTDQAYGTMIRSH

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI145693208, Length=245, Percent_Identity=29.7959183673469, Blast_Score=92, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=283, Percent_Identity=27.9151943462898, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 31988; Mature: 31857

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPNIQPDLLGIAPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVL
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHEEE
LKLVGMNPVVVHGGGPQIEQALNRLGKKGEFIQGMRVTDAETMEVVEWVLAGEVQQDIVG
EEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LIHQAGGKAVGLTGRDGGMIRAKKLKMVDNKDPSVEHDVGQVGDIVAIDPSVVKALQDDA
HHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHCCCCEEEECHHHHHHHHCCC
FIPVISPIGFGEENESYNINADVVASKLATVLQAEKLVLLTNTPGVLDKEGKLLTDLTAR
CEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEHHHHHH
EIDALFADGTISGGMLPKISGALDAAKAGVNAVHIIDGRVPHSMLLEILTDQAYGTMIRS
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
H
C
>Mature Secondary Structure 
PPNIQPDLLGIAPRDKAEILAQALPYIRKFHGKTMVIKYGGNAMTDPALQADFAEDVVL
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHEEE
LKLVGMNPVVVHGGGPQIEQALNRLGKKGEFIQGMRVTDAETMEVVEWVLAGEVQQDIVG
EEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LIHQAGGKAVGLTGRDGGMIRAKKLKMVDNKDPSVEHDVGQVGDIVAIDPSVVKALQDDA
HHHHCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCCHHCCCCEEEECHHHHHHHHCCC
FIPVISPIGFGEENESYNINADVVASKLATVLQAEKLVLLTNTPGVLDKEGKLLTDLTAR
CEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEHHHHHH
EIDALFADGTISGGMLPKISGALDAAKAGVNAVHIIDGRVPHSMLLEILTDQAYGTMIRS
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA