Click here to switch to the map view.

The map label for this gene is dppC [H]

Identifier: 222102802

GI number: 222102802

Start: 465891

End: 466778

Strand: Direct

Name: dppC [H]

Synonym: Avi_7518

Alternate gene names: 222102802

Gene position: 465891-466778 (Clockwise)

Preceding gene: 222102801

Following gene: 222102803

Centisome position: 73.74

GC content: 54.95

Gene sequence:

>888_bases
ATGACGAAAACAAGCGCAACCGTAAATGAGCCTATCCAACGCAGCGCTGGCAGAATGCTGGCGGGCCGTCTTTTCGCACG
TGGTTTAATCGTTCAGGCCTGCTTTGCGATCCTTGTCCTGTTTGGGCTTTTGGCCCTGTTCGCCGATCTTGTCGCGCCTT
ATGACCCGAACGCGCAGGATCTCGTGGCAGCCCTGCACACGCCGTCTGCGGCCCATTGGCTTGGGCAAGACAGCCTCGGC
CGTGATGTGGTGAGCCGCATCATCTATGGCGGACGTATTTCCATGGCCGTCAGTGTCATGGCAGGCATTCTGGCCGCCAT
TGTGGGCATTGGTTTTGGCCTGTACGCGGGCTATGTGGGTGGCAAACCCAGCCGTTTTATCATGGGCTGTACCGATGTCC
TGCTCAGTGTGCCCAATCTGGTTTTTTCCCTCATTCTTGTGGCCATTCTGGGCAGTGGGGTTTTGAGCGTTGTGCTTGCC
ATTGGCATCGGATTCATTCCCACCTACATCCGCATGGTCAATGGGTTGGTCTTATCGTTGCGCGAGCATGACTATATTCT
GGCCGCCCGTCTGATTGGTCAAAAGCCGCATTCCATTCTTTTGAGGCATCTGTTGCCCAATAGTTTTCCAACCTTGATTG
TGCTGTTCACCATCAATCTGGGCAATGGCGTGCTGACGGAATCGACCCTCAGCTACCTTGGTGTTGGCATAGGTCCACCA
ACGGCATCGTGGGGCAGCATGGTGTCGGATGTTTATCCCTACCTCATGAGCGCGCCGTGGCTGGTGGTCAGCCCTGCACT
TTGCATCATCTTGGTAATCATTGCATTCAATGTGGTGGGTGACAGCCTGCGCGATGCGCTTGATCCTCGCTTAAAGGGGA
AATTGTGA

Upstream 100 bases:

>100_bases
CTGGTGATTTCCATGGCGACAATTGCATCCAACCTGATGGTGGACCTGACCTATGCCCTGATCGATCCGCGCATAAAAAG
AATGGCATGGTGATGCCGAT

Downstream 100 bases:

>100_bases
TGACCCAGACCCCTCACTTGCTGGAGGTGAAAAACCTCAGAACATCCTTCTTCACCGAGGACGGTGAAGTGAAAGCTGTC
AATGATGTTTCCTATCATCT

Product: ABC transporter membrane spanning protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTKTSATVNEPIQRSAGRMLAGRLFARGLIVQACFAILVLFGLLALFADLVAPYDPNAQDLVAALHTPSAAHWLGQDSLG
RDVVSRIIYGGRISMAVSVMAGILAAIVGIGFGLYAGYVGGKPSRFIMGCTDVLLSVPNLVFSLILVAILGSGVLSVVLA
IGIGFIPTYIRMVNGLVLSLREHDYILAARLIGQKPHSILLRHLLPNSFPTLIVLFTINLGNGVLTESTLSYLGVGIGPP
TASWGSMVSDVYPYLMSAPWLVVSPALCIILVIIAFNVVGDSLRDALDPRLKGKL

Sequences:

>Translated_295_residues
MTKTSATVNEPIQRSAGRMLAGRLFARGLIVQACFAILVLFGLLALFADLVAPYDPNAQDLVAALHTPSAAHWLGQDSLG
RDVVSRIIYGGRISMAVSVMAGILAAIVGIGFGLYAGYVGGKPSRFIMGCTDVLLSVPNLVFSLILVAILGSGVLSVVLA
IGIGFIPTYIRMVNGLVLSLREHDYILAARLIGQKPHSILLRHLLPNSFPTLIVLFTINLGNGVLTESTLSYLGVGIGPP
TASWGSMVSDVYPYLMSAPWLVVSPALCIILVIIAFNVVGDSLRDALDPRLKGKL
>Mature_294_residues
TKTSATVNEPIQRSAGRMLAGRLFARGLIVQACFAILVLFGLLALFADLVAPYDPNAQDLVAALHTPSAAHWLGQDSLGR
DVVSRIIYGGRISMAVSVMAGILAAIVGIGFGLYAGYVGGKPSRFIMGCTDVLLSVPNLVFSLILVAILGSGVLSVVLAI
GIGFIPTYIRMVNGLVLSLREHDYILAARLIGQKPHSILLRHLLPNSFPTLIVLFTINLGNGVLTESTLSYLGVGIGPPT
ASWGSMVSDVYPYLMSAPWLVVSPALCIILVIIAFNVVGDSLRDALDPRLKGKL

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=272, Percent_Identity=40.8088235294118, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1787760, Length=293, Percent_Identity=36.518771331058, Blast_Score=195, Evalue=2e-51,
Organism=Escherichia coli, GI1789889, Length=239, Percent_Identity=38.4937238493724, Blast_Score=181, Evalue=5e-47,
Organism=Escherichia coli, GI1789964, Length=256, Percent_Identity=40.625, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787498, Length=294, Percent_Identity=33.6734693877551, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787549, Length=251, Percent_Identity=30.2788844621514, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=31.8385650224215, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31236; Mature: 31104

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTSATVNEPIQRSAGRMLAGRLFARGLIVQACFAILVLFGLLALFADLVAPYDPNAQD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LVAALHTPSAAHWLGQDSLGRDVVSRIIYGGRISMAVSVMAGILAAIVGIGFGLYAGYVG
HHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKPSRFIMGCTDVLLSVPNLVFSLILVAILGSGVLSVVLAIGIGFIPTYIRMVNGLVLSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REHDYILAARLIGQKPHSILLRHLLPNSFPTLIVLFTINLGNGVLTESTLSYLGVGIGPP
HHCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCC
TASWGSMVSDVYPYLMSAPWLVVSPALCIILVIIAFNVVGDSLRDALDPRLKGKL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure 
TKTSATVNEPIQRSAGRMLAGRLFARGLIVQACFAILVLFGLLALFADLVAPYDPNAQD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LVAALHTPSAAHWLGQDSLGRDVVSRIIYGGRISMAVSVMAGILAAIVGIGFGLYAGYVG
HHHHHCCCHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKPSRFIMGCTDVLLSVPNLVFSLILVAILGSGVLSVVLAIGIGFIPTYIRMVNGLVLSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REHDYILAARLIGQKPHSILLRHLLPNSFPTLIVLFTINLGNGVLTESTLSYLGVGIGPP
HHCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCC
TASWGSMVSDVYPYLMSAPWLVVSPALCIILVIIAFNVVGDSLRDALDPRLKGKL
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]