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The map label for this gene is alsB [H]

Identifier: 222102692

GI number: 222102692

Start: 339924

End: 340874

Strand: Direct

Name: alsB [H]

Synonym: Avi_7364

Alternate gene names: 222102692

Gene position: 339924-340874 (Clockwise)

Preceding gene: 222102691

Following gene: 222102693

Centisome position: 53.8

GC content: 60.15

Gene sequence:

>951_bases
ATGGACTGGTCGCAGCTGGAAGCAAAGTTCGGCCCCTTTCCGAAGCTTCCCGACGGCACCAAGGCGGGCGCCGTCTCAAA
GACACTGACCAACGAATACTGGCGGTCGCTCGGTGAGGGCTATGCCGCGTTCGGCAAGGCCAAGAACGTTCCGGTCGCCT
ATCAGGCGGCGCAAAGCGAAGGCGACCAGCTTGGTCAGTTGACGATTGCCGAGGGGATGATCACCCAAGGCTATAACGTT
CTGCTGGTGTCGCCACAGACGGATTCCAATCTCCAACCGGTGATCGAACAGGCCAAGGCCGCCAATATTCCGGTCGTTGA
CGTCAATGATGCCGTGATCCCGCAGGCCGAGCACTATGTCGGCAATGTTCAGCGCGACAACGGCGTGCGCGTCGCCAAAT
GGTTCATCACCAACCGTCCGCAGGGTGGCAAGGTGGCGATCATCGAGGGCCAGGCCGGTGTTTATGCCGCCGTGCAACGC
ACCGACGGCTTTAAATCCACCATCGGTGAAAACGGCAGTTTCAAGATCGTCGCCAGCGTTCCCGGCAATTGGGACCGCCA
GACCTCCTACGATGCCGCGACCAACATCCTCAACCAACACCCCGATCTTATCGGCTTCTATGCCAACAATGACGGCATGG
CATTGGGCGTGGTCGAAGCCGTCAAGGCGGCAGGGCTTGCGGGCAAGGTCGCTGTCTTCGGCACTGACGGTATTTCAGAC
GCCTACGCCTCGATCAAGGCAGGCGAACTGACCGGCACCGTCGATAGCTTTCCGGTTCTAACAGGTGAAGTCGCCCTTGA
AACAGCCCTTCGGCTCGTTGCCGGCCAGAAATTGCCGCGCGTTGTCGCAACGCCTCAGGCGCTGATCACCGCCGACAACC
TCGCCCGCTACCAAGGCAAGGGCGTCGATGTGCGCGCCGTGCTGATGGAAGATGCCAAGGCTGCAAAATAA

Upstream 100 bases:

>100_bases
GAAACTGACGCTTGCCACTGGCCTTGCTGCCAGCTTCCTGTTCAGCGCAGCCTTTGCGCAGCAGCTTGCCCCACTCAATT
CCGACACTGAAAAAGACCGC

Downstream 100 bases:

>100_bases
TCGAGGTTAACGCACTGCCAGCTTTCAGGGCTGGCAGTGCGTGTCTTGCAGGAGGAGGTAAGAGATGGTGCCGAGACTGG
GATTTGAAACAATCTCCAAG

Product: ABC transporter substrate binding protein

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MDWSQLEAKFGPFPKLPDGTKAGAVSKTLTNEYWRSLGEGYAAFGKAKNVPVAYQAAQSEGDQLGQLTIAEGMITQGYNV
LLVSPQTDSNLQPVIEQAKAANIPVVDVNDAVIPQAEHYVGNVQRDNGVRVAKWFITNRPQGGKVAIIEGQAGVYAAVQR
TDGFKSTIGENGSFKIVASVPGNWDRQTSYDAATNILNQHPDLIGFYANNDGMALGVVEAVKAAGLAGKVAVFGTDGISD
AYASIKAGELTGTVDSFPVLTGEVALETALRLVAGQKLPRVVATPQALITADNLARYQGKGVDVRAVLMEDAKAAK

Sequences:

>Translated_316_residues
MDWSQLEAKFGPFPKLPDGTKAGAVSKTLTNEYWRSLGEGYAAFGKAKNVPVAYQAAQSEGDQLGQLTIAEGMITQGYNV
LLVSPQTDSNLQPVIEQAKAANIPVVDVNDAVIPQAEHYVGNVQRDNGVRVAKWFITNRPQGGKVAIIEGQAGVYAAVQR
TDGFKSTIGENGSFKIVASVPGNWDRQTSYDAATNILNQHPDLIGFYANNDGMALGVVEAVKAAGLAGKVAVFGTDGISD
AYASIKAGELTGTVDSFPVLTGEVALETALRLVAGQKLPRVVATPQALITADNLARYQGKGVDVRAVLMEDAKAAK
>Mature_316_residues
MDWSQLEAKFGPFPKLPDGTKAGAVSKTLTNEYWRSLGEGYAAFGKAKNVPVAYQAAQSEGDQLGQLTIAEGMITQGYNV
LLVSPQTDSNLQPVIEQAKAANIPVVDVNDAVIPQAEHYVGNVQRDNGVRVAKWFITNRPQGGKVAIIEGQAGVYAAVQR
TDGFKSTIGENGSFKIVASVPGNWDRQTSYDAATNILNQHPDLIGFYANNDGMALGVVEAVKAAGLAGKVAVFGTDGISD
AYASIKAGELTGTVDSFPVLTGEVALETALRLVAGQKLPRVVATPQALITADNLARYQGKGVDVRAVLMEDAKAAK

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=272, Percent_Identity=34.1911764705882, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1790192, Length=271, Percent_Identity=29.520295202952, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790674, Length=241, Percent_Identity=26.5560165975104, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 33307; Mature: 33307

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWSQLEAKFGPFPKLPDGTKAGAVSKTLTNEYWRSLGEGYAAFGKAKNVPVAYQAAQSE
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHCC
GDQLGQLTIAEGMITQGYNVLLVSPQTDSNLQPVIEQAKAANIPVVDVNDAVIPQAEHYV
CCHHCEEEEECCHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHH
GNVQRDNGVRVAKWFITNRPQGGKVAIIEGQAGVYAAVQRTDGFKSTIGENGSFKIVASV
CCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCCEEEEEEC
PGNWDRQTSYDAATNILNQHPDLIGFYANNDGMALGVVEAVKAAGLAGKVAVFGTDGISD
CCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCEEEEEECCCCCH
AYASIKAGELTGTVDSFPVLTGEVALETALRLVAGQKLPRVVATPQALITADNLARYQGK
HHHHEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHCCCHHEEEHHHHHHHCCC
GVDVRAVLMEDAKAAK
CCCEEEEEECCCCCCC
>Mature Secondary Structure
MDWSQLEAKFGPFPKLPDGTKAGAVSKTLTNEYWRSLGEGYAAFGKAKNVPVAYQAAQSE
CCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHCC
GDQLGQLTIAEGMITQGYNVLLVSPQTDSNLQPVIEQAKAANIPVVDVNDAVIPQAEHYV
CCHHCEEEEECCHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCHHHHH
GNVQRDNGVRVAKWFITNRPQGGKVAIIEGQAGVYAAVQRTDGFKSTIGENGSFKIVASV
CCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCEEEEEECCCCHHHHHCCCCCEEEEEEC
PGNWDRQTSYDAATNILNQHPDLIGFYANNDGMALGVVEAVKAAGLAGKVAVFGTDGISD
CCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCEEHHHHHHHHCCCCCEEEEEECCCCCH
AYASIKAGELTGTVDSFPVLTGEVALETALRLVAGQKLPRVVATPQALITADNLARYQGK
HHHHEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHCCCHHEEEHHHHHHHCCC
GVDVRAVLMEDAKAAK
CCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]