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The map label for this gene is eryA [H]

Identifier: 222102650

GI number: 222102650

Start: 278797

End: 283257

Strand: Direct

Name: eryA [H]

Synonym: Avi_7309

Alternate gene names: 222102650

Gene position: 278797-283257 (Clockwise)

Preceding gene: 222102649

Following gene: 222102651

Centisome position: 44.13

GC content: 61.85

Gene sequence:

>4461_bases
ATGGCCGGGCGCTTTCCCGGTGCCGATGATATCGATGCGTTCTGGGATCTTTTGGAGCAAGGTCAAAGCGGCCTTCGCTC
TGTCACGGATCACGAATTGCAAGAGGCTGGCGTCGATCCCACGATGGCGGCCCGGCCGGATTATGTCCGCGTCTGGGGTG
GCTTCGACGATCCAACGGCTTTCGATGCCGGTTTCTTCGGCTATTCGCCGCGCGATGCGGAATTGCTGGATCCACAACAT
CGTGTCTTCCTCGAATGCGCAGCGAATGCACTCGACCATGCGGGCTATAACAGCGCCACCTATGCCGGGCGTATCGGCGT
CTTTGCCGGTGGCGCGCTCAACTATCATTTCAGCCAGATACAGGCCAATCCGCAGCTCAGGGAGGCAACGGACCCGATCC
ATGCGGGCCTTGGCAATGTGCTTGGCATGATTGCTTCGCGTGTCGCCTATCACCTTGATCTCACCGGGCCAACCGTAGGC
GTTCAGGCGACTTGTGCCACGGCGCTCGTGGCGCTTCATCTCGCGGCACGCGGCCTGTTAGCGCGTGAGGCGGATATGGC
GCTGGCGGGTGCCATCGCCATCGGCCAACCGCGCCCGGAAGGCTATCTCTACAAGAGCGAAGGCATCGCCTCCCCGGACG
GGGCATGCCGTCCGTTTGACGCCAATGCCAAGGGCACCGTGTTCACCAATGGCGTCGGCGTCCTCGTTCTCAAACGGCTG
AGCGACGCGATTGCTGACGGCGATACAATTCATGCTGTTCTCAGCGGCTCGGCCATCGGCAATGACGGTTCCGCCAAAGT
CGGGTTAACAGCGCCCAGCGTTGCCGGGCAAACGGCGGTGCTTCAGGCAGCCCTTGCCGACGCCCGCCTTGACGCCTCTG
AGGTGGACTATGTCGAAGCACACGGAACCGCCACGACCCTCGGCGATCCCATCGAAATCCGCGCCCTGTCCAGTGTGTAT
GGCGATACGCTGAAACAGCAGGGCCGCCGCTGCGGTCTTGGTTCTGTAAAGGGCAATCTCGGACATATGGATGTGGCCGC
CGGAATGGGAGGGCTGATCAAGACCATTCTTGCGCTGAAGCACCAGATCCTGCCCGCCAGCATCAATTTTACCAGCGCGA
ACCCGGCCCTTGATCTGGCGGCGAGTCCTTTCGACATCGTGGCGCAGCAGCGGCCTTGGCCGGTGACAGAGCTGCGCAAG
CGTCGCGCGGCCATAAGCGCCTTTGGCATGGGCGGGATGAATGCGCATGTGATCATTGAAGAGCCGCCGGTTCGGGATAG
CGAAGCGGACACCACTGGGCCTTATCTCTTGCCACTCTCGGCCAAGACGCCCGAAGCGCTGGCGGCGATGCGAAGCGCTG
TGGCCGATCATCTTGGCACCGATGATGGAGCAAAGCTTGCCGATATTGCCTATACCCTCCGGCAGGGCCGTCGGACGATG
GAGCATCGCTTTGTCGCCCTCGCAAAGGACAGAGACGCTGCCGCGCAGATCATCCGCAGCGGAGAAGGCCCCCATTGTGT
CGCGGGTGAGCCGCTGGCTGGCGATGCAAGTTTGATCCTGCTGTTTCCCGGACAGGGAGCACAATATCCGGGAATGGCGC
GGGCGCTGTACGAGACGAATGCAACATTCCGCACCGCCTTCGATGCCTGCCTGCGCTTGATGCCGCAGGAACTTGACCTT
GCGGCCATCATCTTTGGCGATGGCACAACGACAGAGCAACTTTCCCGCACAGAGATAACGCAGCCAGCACTTTTCGCAAT
CGAGTATGCGCTGGCGCAGATGTGGCTTGCCAAGGGCATCAAGCCACGGGCCATGGTCGGTCACAGTCTCGGGGAATATG
TTGCGGCCTGCCTTGCCGGGGTCTTCTCGCTGCAAGATGCGGTGACGCTGATTGTTGCCCGTGGGCGGCTGATGCAGGCC
TGCCCGCCCGGTGCCATGCTCTCCGTTATGCTCTCAGAACAAGAGGCGCGCGCATCGCTTTCGCCAGACGTGGACCTTGC
TGCCGTCAACGGTCCGCGCAGCACGGTTCTGGCGGGCACGGCAGAGGCAATTGCCGAACTCGCGGCCCGGTTTGATCGCA
GCGGTATCGGCAGGCAAGACCTCAAGACCTCCCATGCCTTTCACAGCTTCATGATGGAGCCTGCGCTTGAAGCGTTTGCG
CAGGTGCTCGGCACGGTGACGCTCAACCCGCCGCAGATTGACATTGTCTCGAACCTGACGGGCGATTGGCTGACGGCACA
GGAGGCGACCGACCCAGCCTATTGGGTGGCCCATCTGCGCCAAACCGTTCTGTTTGGCCCCTGCCTTGCGCGGGTGCTTG
AATTGCCGGCCCCGTTTCTTCTCGAAGTCGGACCCGGCTCCACACTCACCCGGCTTGCACGCCAGCAAGGAAAGGCTCAG
CTTCGCGTTGCCACCTCGCTGCCCGATGCGAAGGCGCTGCTCGACGCCTGCGACCACGCGCTGCTGGCATTGGCGGAGCT
TTGGATCGCGGGCATTGATGTCGAACTTGTTGCCGAAAAAGATGCAGGCCCGCGCCGCCGCGTGCCACTTCCAACCTACC
CTTTTCAGCGCAGTTCCTACGCGATTGCGCGGATTGCACCAACCGAATCCATGCCCGACGAAGCGGCCCGGCAACCATCA
ATCGAGGACTGGCTTTACCAGCCGGTCTGGCAACGTGCGCCCATTGAGCATCTCACAACGAGCGGTCACGAGCATTGGTT
GATTCTTGGCGGCGAAGAGACTGTCGCCGCGATCGGTCCGGTTTCGGATCAGATCAAGGTCACACGGGTACGGTCTGGCA
TAGCCTATGAAAATGCCGGGGGCACGTATCACATCGACTCCGCTGACCCACAGCACTACAGCGCAGTTCTTGCTGATCTT
GCCGCCAACGGTGCAACACTGACCCAGATTGTCAATGGCTTCTCCCTTGATGCCAACGCTGCCCCGGACACAGCTTTCGC
CAGCAGTTTTGCGCTCGCGAAAGCCCTGACCACAACCGAGAGCCGCCCGCCGCTTCTGACTGTTCTGGCATGCGGCCTGC
ATGCTGTGACTGGCGCAGAGGTTGTTGATGCGCAGGCGGCCAAAGTGCTTGGCATGCTCCGCGTCTTGTCGCAGGAAATT
CCGGGCATCTCCTGCCGAAGCATCGATTTTCCATCGGCAGAAGGTGCCATTGTGCCCGGCCTCGCTGAGGCGCTATCACG
CCCTTGGCGTGACGATAGAACCGTGATGGCGCTGCGCAATGGCTATTGCTGGGTTGAGAGCCACGTGCCGACGTGCCTGC
CGGAGCCAGCCGATGTTCCGGCTCTCACGGCGGGGGCCACCTACCTCATCGCAGGCGATCTCCTCGACGGTCTCGCTCTC
GTTTATGCTAGGTCGCTGGTTCAAACACTGGGCGCGAAGGTTGTCCTTGTTGGACCAAGCGGGCTTCCGAATGCTGCGGA
TTGGGAACACTGGCTTGCCTCGCACGGGCCGAAGCATCCGGTGAGCGCATTGATCCGGGCTTTGCGCGGCATTGGCACAC
CGGGCGAGGATTACGTGCTGTTCAGCGGTGATCTCGCTGACCCTGCTTGGCTTGCCACATGCCTCAACTCGCTTGGCGCA
CCATTTGGCCCGATCCGTGGGGCTTTCCAGACGGCGGCTATGGGCGAGGTTTATCACTGCCCGCTCACAGAGGCCACAGT
CGAGCGCAATGCTGCACTGTTTGCAACTAAGGTTGATGGCTTGAACGCTCTGTCAGCGGCGCTTGCCGATCACACCCCCG
ATTTCGTCCTCGTTCAGTCCTCCCTCTCAACGCTGGTGGGCGGTGCGGGGCTTGCCGCCTATGCAGGGGCCAATAGCTTT
CTTGATGCCTTTGTTGATGCACGGCGCGGCGCACATCGTCCGGTCTGGCAGGCAATCGCGTGGGATACATGCCTTCCTTT
TGGCACCACGCGAGAGGAGGCAACAGGCTTTCTTAACGACGCGATTGACGCCGACGAGGTCTGGCGGGCAACCCGGGCGG
TTCTTGCCCAGCCACAGGTCTCCCGGCTTGCCGTGACGCCGGTTGATCTGCGCCATCGCATGGCCGCAGCGCGGCAGGAA
CCAAGGGCCGGTGTGGCTGTAGATCAGCAGGAGAACATCGGGCGCGAGCGTGTGCAGGCAGCGTTCATCGCCCCGCGTGA
TCCCATCGAGACCGATGTGGCGGCTGTTATCGGGGAACTCCTTGGCATTTCCCGTGTTGGAATCGATGACAATTTCTTCG
AGCTTGGTGGGCATTCCCTGCTTGCCGTGCAGGTCGTGACGCGGTTGCGCAAGCAATTCTCAATCGAGTTGCCCATGCGC
GCCCTGCTGTTTGATGCGCCCACTGTCGGGGGCATCGCGGCCGTCATCCGTGAGCGCCTTGAGGCCGCACGGAAAGAACA
GGCAGAGCTTGCCGCCCTTCTGGACGACATTGAGGCAGAGGCGCTCCGCAAGGAAGCCTGA

Upstream 100 bases:

>100_bases
CATGGTTGACCAGGATGAGATCCTCTCGATTTTAAAAGATGCGCGCGCGCGTCTGGAGGCGGCGCAAAGGGAGAAGGACG
AGCGCGTGGCAATCGTCGGC

Downstream 100 bases:

>100_bases
CTGTCACCTGCCTTCCATCAGCAATACGTAAAGGAATGACGACGATGAAATTCAGCCTGTTTTATTTCGATGGCGATGGC
TCTGCTACGAACGGTGACAG

Product: polyketide synthase

Products: NA

Alternate protein names: 6-deoxyerythronolide B synthase III; DEBS 3; ORF 3 [H]

Number of amino acids: Translated: 1486; Mature: 1485

Protein sequence:

>1486_residues
MAGRFPGADDIDAFWDLLEQGQSGLRSVTDHELQEAGVDPTMAARPDYVRVWGGFDDPTAFDAGFFGYSPRDAELLDPQH
RVFLECAANALDHAGYNSATYAGRIGVFAGGALNYHFSQIQANPQLREATDPIHAGLGNVLGMIASRVAYHLDLTGPTVG
VQATCATALVALHLAARGLLAREADMALAGAIAIGQPRPEGYLYKSEGIASPDGACRPFDANAKGTVFTNGVGVLVLKRL
SDAIADGDTIHAVLSGSAIGNDGSAKVGLTAPSVAGQTAVLQAALADARLDASEVDYVEAHGTATTLGDPIEIRALSSVY
GDTLKQQGRRCGLGSVKGNLGHMDVAAGMGGLIKTILALKHQILPASINFTSANPALDLAASPFDIVAQQRPWPVTELRK
RRAAISAFGMGGMNAHVIIEEPPVRDSEADTTGPYLLPLSAKTPEALAAMRSAVADHLGTDDGAKLADIAYTLRQGRRTM
EHRFVALAKDRDAAAQIIRSGEGPHCVAGEPLAGDASLILLFPGQGAQYPGMARALYETNATFRTAFDACLRLMPQELDL
AAIIFGDGTTTEQLSRTEITQPALFAIEYALAQMWLAKGIKPRAMVGHSLGEYVAACLAGVFSLQDAVTLIVARGRLMQA
CPPGAMLSVMLSEQEARASLSPDVDLAAVNGPRSTVLAGTAEAIAELAARFDRSGIGRQDLKTSHAFHSFMMEPALEAFA
QVLGTVTLNPPQIDIVSNLTGDWLTAQEATDPAYWVAHLRQTVLFGPCLARVLELPAPFLLEVGPGSTLTRLARQQGKAQ
LRVATSLPDAKALLDACDHALLALAELWIAGIDVELVAEKDAGPRRRVPLPTYPFQRSSYAIARIAPTESMPDEAARQPS
IEDWLYQPVWQRAPIEHLTTSGHEHWLILGGEETVAAIGPVSDQIKVTRVRSGIAYENAGGTYHIDSADPQHYSAVLADL
AANGATLTQIVNGFSLDANAAPDTAFASSFALAKALTTTESRPPLLTVLACGLHAVTGAEVVDAQAAKVLGMLRVLSQEI
PGISCRSIDFPSAEGAIVPGLAEALSRPWRDDRTVMALRNGYCWVESHVPTCLPEPADVPALTAGATYLIAGDLLDGLAL
VYARSLVQTLGAKVVLVGPSGLPNAADWEHWLASHGPKHPVSALIRALRGIGTPGEDYVLFSGDLADPAWLATCLNSLGA
PFGPIRGAFQTAAMGEVYHCPLTEATVERNAALFATKVDGLNALSAALADHTPDFVLVQSSLSTLVGGAGLAAYAGANSF
LDAFVDARRGAHRPVWQAIAWDTCLPFGTTREEATGFLNDAIDADEVWRATRAVLAQPQVSRLAVTPVDLRHRMAAARQE
PRAGVAVDQQENIGRERVQAAFIAPRDPIETDVAAVIGELLGISRVGIDDNFFELGGHSLLAVQVVTRLRKQFSIELPMR
ALLFDAPTVGGIAAVIRERLEAARKEQAELAALLDDIEAEALRKEA

Sequences:

>Translated_1486_residues
MAGRFPGADDIDAFWDLLEQGQSGLRSVTDHELQEAGVDPTMAARPDYVRVWGGFDDPTAFDAGFFGYSPRDAELLDPQH
RVFLECAANALDHAGYNSATYAGRIGVFAGGALNYHFSQIQANPQLREATDPIHAGLGNVLGMIASRVAYHLDLTGPTVG
VQATCATALVALHLAARGLLAREADMALAGAIAIGQPRPEGYLYKSEGIASPDGACRPFDANAKGTVFTNGVGVLVLKRL
SDAIADGDTIHAVLSGSAIGNDGSAKVGLTAPSVAGQTAVLQAALADARLDASEVDYVEAHGTATTLGDPIEIRALSSVY
GDTLKQQGRRCGLGSVKGNLGHMDVAAGMGGLIKTILALKHQILPASINFTSANPALDLAASPFDIVAQQRPWPVTELRK
RRAAISAFGMGGMNAHVIIEEPPVRDSEADTTGPYLLPLSAKTPEALAAMRSAVADHLGTDDGAKLADIAYTLRQGRRTM
EHRFVALAKDRDAAAQIIRSGEGPHCVAGEPLAGDASLILLFPGQGAQYPGMARALYETNATFRTAFDACLRLMPQELDL
AAIIFGDGTTTEQLSRTEITQPALFAIEYALAQMWLAKGIKPRAMVGHSLGEYVAACLAGVFSLQDAVTLIVARGRLMQA
CPPGAMLSVMLSEQEARASLSPDVDLAAVNGPRSTVLAGTAEAIAELAARFDRSGIGRQDLKTSHAFHSFMMEPALEAFA
QVLGTVTLNPPQIDIVSNLTGDWLTAQEATDPAYWVAHLRQTVLFGPCLARVLELPAPFLLEVGPGSTLTRLARQQGKAQ
LRVATSLPDAKALLDACDHALLALAELWIAGIDVELVAEKDAGPRRRVPLPTYPFQRSSYAIARIAPTESMPDEAARQPS
IEDWLYQPVWQRAPIEHLTTSGHEHWLILGGEETVAAIGPVSDQIKVTRVRSGIAYENAGGTYHIDSADPQHYSAVLADL
AANGATLTQIVNGFSLDANAAPDTAFASSFALAKALTTTESRPPLLTVLACGLHAVTGAEVVDAQAAKVLGMLRVLSQEI
PGISCRSIDFPSAEGAIVPGLAEALSRPWRDDRTVMALRNGYCWVESHVPTCLPEPADVPALTAGATYLIAGDLLDGLAL
VYARSLVQTLGAKVVLVGPSGLPNAADWEHWLASHGPKHPVSALIRALRGIGTPGEDYVLFSGDLADPAWLATCLNSLGA
PFGPIRGAFQTAAMGEVYHCPLTEATVERNAALFATKVDGLNALSAALADHTPDFVLVQSSLSTLVGGAGLAAYAGANSF
LDAFVDARRGAHRPVWQAIAWDTCLPFGTTREEATGFLNDAIDADEVWRATRAVLAQPQVSRLAVTPVDLRHRMAAARQE
PRAGVAVDQQENIGRERVQAAFIAPRDPIETDVAAVIGELLGISRVGIDDNFFELGGHSLLAVQVVTRLRKQFSIELPMR
ALLFDAPTVGGIAAVIRERLEAARKEQAELAALLDDIEAEALRKEA
>Mature_1485_residues
AGRFPGADDIDAFWDLLEQGQSGLRSVTDHELQEAGVDPTMAARPDYVRVWGGFDDPTAFDAGFFGYSPRDAELLDPQHR
VFLECAANALDHAGYNSATYAGRIGVFAGGALNYHFSQIQANPQLREATDPIHAGLGNVLGMIASRVAYHLDLTGPTVGV
QATCATALVALHLAARGLLAREADMALAGAIAIGQPRPEGYLYKSEGIASPDGACRPFDANAKGTVFTNGVGVLVLKRLS
DAIADGDTIHAVLSGSAIGNDGSAKVGLTAPSVAGQTAVLQAALADARLDASEVDYVEAHGTATTLGDPIEIRALSSVYG
DTLKQQGRRCGLGSVKGNLGHMDVAAGMGGLIKTILALKHQILPASINFTSANPALDLAASPFDIVAQQRPWPVTELRKR
RAAISAFGMGGMNAHVIIEEPPVRDSEADTTGPYLLPLSAKTPEALAAMRSAVADHLGTDDGAKLADIAYTLRQGRRTME
HRFVALAKDRDAAAQIIRSGEGPHCVAGEPLAGDASLILLFPGQGAQYPGMARALYETNATFRTAFDACLRLMPQELDLA
AIIFGDGTTTEQLSRTEITQPALFAIEYALAQMWLAKGIKPRAMVGHSLGEYVAACLAGVFSLQDAVTLIVARGRLMQAC
PPGAMLSVMLSEQEARASLSPDVDLAAVNGPRSTVLAGTAEAIAELAARFDRSGIGRQDLKTSHAFHSFMMEPALEAFAQ
VLGTVTLNPPQIDIVSNLTGDWLTAQEATDPAYWVAHLRQTVLFGPCLARVLELPAPFLLEVGPGSTLTRLARQQGKAQL
RVATSLPDAKALLDACDHALLALAELWIAGIDVELVAEKDAGPRRRVPLPTYPFQRSSYAIARIAPTESMPDEAARQPSI
EDWLYQPVWQRAPIEHLTTSGHEHWLILGGEETVAAIGPVSDQIKVTRVRSGIAYENAGGTYHIDSADPQHYSAVLADLA
ANGATLTQIVNGFSLDANAAPDTAFASSFALAKALTTTESRPPLLTVLACGLHAVTGAEVVDAQAAKVLGMLRVLSQEIP
GISCRSIDFPSAEGAIVPGLAEALSRPWRDDRTVMALRNGYCWVESHVPTCLPEPADVPALTAGATYLIAGDLLDGLALV
YARSLVQTLGAKVVLVGPSGLPNAADWEHWLASHGPKHPVSALIRALRGIGTPGEDYVLFSGDLADPAWLATCLNSLGAP
FGPIRGAFQTAAMGEVYHCPLTEATVERNAALFATKVDGLNALSAALADHTPDFVLVQSSLSTLVGGAGLAAYAGANSFL
DAFVDARRGAHRPVWQAIAWDTCLPFGTTREEATGFLNDAIDADEVWRATRAVLAQPQVSRLAVTPVDLRHRMAAARQEP
RAGVAVDQQENIGRERVQAAFIAPRDPIETDVAAVIGELLGISRVGIDDNFFELGGHSLLAVQVVTRLRKQFSIELPMRA
LLFDAPTVGGIAAVIRERLEAARKEQAELAALLDDIEAEALRKEA

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG3321

COG function: function code Q; Polyketide synthase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI41872631, Length=891, Percent_Identity=26.8237934904602, Blast_Score=244, Evalue=5e-64,
Organism=Homo sapiens, GI8923559, Length=287, Percent_Identity=29.616724738676, Blast_Score=101, Evalue=6e-21,
Organism=Homo sapiens, GI51243059, Length=321, Percent_Identity=28.6604361370716, Blast_Score=79, Evalue=5e-14,
Organism=Homo sapiens, GI223972627, Length=154, Percent_Identity=33.1168831168831, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787337, Length=289, Percent_Identity=29.757785467128, Blast_Score=97, Evalue=9e-21,
Organism=Escherichia coli, GI1787334, Length=291, Percent_Identity=31.9587628865979, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788663, Length=211, Percent_Identity=31.2796208530806, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=805, Percent_Identity=28.4472049689441, Blast_Score=293, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI212642053, Length=859, Percent_Identity=26.0768335273574, Blast_Score=236, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI71983541, Length=281, Percent_Identity=29.1814946619217, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=30.1115241635688, Blast_Score=103, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320904, Length=353, Percent_Identity=26.628895184136, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI19920632, Length=795, Percent_Identity=26.0377358490566, Blast_Score=216, Evalue=1e-55,
Organism=Drosophila melanogaster, GI221330659, Length=737, Percent_Identity=26.3229308005427, Blast_Score=215, Evalue=2e-55,
Organism=Drosophila melanogaster, GI24581345, Length=818, Percent_Identity=25.3056234718826, Blast_Score=207, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24644341, Length=286, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24665753, Length=341, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR009081
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR000794
- InterPro:   IPR002198
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016036
- InterPro:   IPR016040
- InterPro:   IPR006163
- InterPro:   IPR020842
- InterPro:   IPR020801
- InterPro:   IPR020841
- InterPro:   IPR020806
- InterPro:   IPR020802
- InterPro:   IPR015083
- InterPro:   IPR006162
- InterPro:   IPR001031
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00698 Acyl_transf_1; PF00106 adh_short; PF08990 Docking; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: =2.3.1.94 [H]

Molecular weight: Translated: 157153; Mature: 157022

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRFPGADDIDAFWDLLEQGQSGLRSVTDHELQEAGVDPTMAARPDYVRVWGGFDDPTA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC
FDAGFFGYSPRDAELLDPQHRVFLECAANALDHAGYNSATYAGRIGVFAGGALNYHFSQI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
QANPQLREATDPIHAGLGNVLGMIASRVAYHLDLTGPTVGVQATCATALVALHLAARGLL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AREADMALAGAIAIGQPRPEGYLYKSEGIASPDGACRPFDANAKGTVFTNGVGVLVLKRL
HHHHHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
SDAIADGDTIHAVLSGSAIGNDGSAKVGLTAPSVAGQTAVLQAALADARLDASEVDYVEA
HHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHCCEEEC
HGTATTLGDPIEIRALSSVYGDTLKQQGRRCGLGSVKGNLGHMDVAAGMGGLIKTILALK
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
HQILPASINFTSANPALDLAASPFDIVAQQRPWPVTELRKRRAAISAFGMGGMNAHVIIE
HHHCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
EPPVRDSEADTTGPYLLPLSAKTPEALAAMRSAVADHLGTDDGAKLADIAYTLRQGRRTM
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EHRFVALAKDRDAAAQIIRSGEGPHCVAGEPLAGDASLILLFPGQGAQYPGMARALYETN
HHHHHHEECCHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCC
ATFRTAFDACLRLMPQELDLAAIIFGDGTTTEQLSRTEITQPALFAIEYALAQMWLAKGI
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
KPRAMVGHSLGEYVAACLAGVFSLQDAVTLIVARGRLMQACPPGAMLSVMLSEQEARASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCC
SPDVDLAAVNGPRSTVLAGTAEAIAELAARFDRSGIGRQDLKTSHAFHSFMMEPALEAFA
CCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVLGTVTLNPPQIDIVSNLTGDWLTAQEATDPAYWVAHLRQTVLFGPCLARVLELPAPFL
HHHCCCCCCCCCEEHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LEVGPGSTLTRLARQQGKAQLRVATSLPDAKALLDACDHALLALAELWIAGIDVELVAEK
EEECCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
DAGPRRRVPLPTYPFQRSSYAIARIAPTESMPDEAARQPSIEDWLYQPVWQRAPIEHLTT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHC
SGHEHWLILGGEETVAAIGPVSDQIKVTRVRSGIAYENAGGTYHIDSADPQHYSAVLADL
CCCCEEEEECCCCCEEEECCCCCCEEEEEHHCCCEEECCCCEEEECCCCCHHHHHHHHHH
AANGATLTQIVNGFSLDANAAPDTAFASSFALAKALTTTESRPPLLTVLACGLHAVTGAE
HCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCH
VVDAQAAKVLGMLRVLSQEIPGISCRSIDFPSAEGAIVPGLAEALSRPWRDDRTVMALRN
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEC
GYCWVESHVPTCLPEPADVPALTAGATYLIAGDLLDGLALVYARSLVQTLGAKVVLVGPS
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GLPNAADWEHWLASHGPKHPVSALIRALRGIGTPGEDYVLFSGDLADPAWLATCLNSLGA
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
PFGPIRGAFQTAAMGEVYHCPLTEATVERNAALFATKVDGLNALSAALADHTPDFVLVQS
CCCHHHHHHHHHHCCCEEECCCCHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHH
SLSTLVGGAGLAAYAGANSFLDAFVDARRGAHRPVWQAIAWDTCLPFGTTREEATGFLND
HHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AIDADEVWRATRAVLAQPQVSRLAVTPVDLRHRMAAARQEPRAGVAVDQQENIGRERVQA
CCCHHHHHHHHHHHHCCCCHHHEEECCHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHH
AFIAPRDPIETDVAAVIGELLGISRVGIDDNFFELGGHSLLAVQVVTRLRKQFSIELPMR
HCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
ALLFDAPTVGGIAAVIRERLEAARKEQAELAALLDDIEAEALRKEA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGRFPGADDIDAFWDLLEQGQSGLRSVTDHELQEAGVDPTMAARPDYVRVWGGFDDPTA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCC
FDAGFFGYSPRDAELLDPQHRVFLECAANALDHAGYNSATYAGRIGVFAGGALNYHFSQI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHH
QANPQLREATDPIHAGLGNVLGMIASRVAYHLDLTGPTVGVQATCATALVALHLAARGLL
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AREADMALAGAIAIGQPRPEGYLYKSEGIASPDGACRPFDANAKGTVFTNGVGVLVLKRL
HHHHHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHH
SDAIADGDTIHAVLSGSAIGNDGSAKVGLTAPSVAGQTAVLQAALADARLDASEVDYVEA
HHHHCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHCCEEEC
HGTATTLGDPIEIRALSSVYGDTLKQQGRRCGLGSVKGNLGHMDVAAGMGGLIKTILALK
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
HQILPASINFTSANPALDLAASPFDIVAQQRPWPVTELRKRRAAISAFGMGGMNAHVIIE
HHHCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
EPPVRDSEADTTGPYLLPLSAKTPEALAAMRSAVADHLGTDDGAKLADIAYTLRQGRRTM
CCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
EHRFVALAKDRDAAAQIIRSGEGPHCVAGEPLAGDASLILLFPGQGAQYPGMARALYETN
HHHHHHEECCHHHHHHHHHCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHCC
ATFRTAFDACLRLMPQELDLAAIIFGDGTTTEQLSRTEITQPALFAIEYALAQMWLAKGI
CHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
KPRAMVGHSLGEYVAACLAGVFSLQDAVTLIVARGRLMQACPPGAMLSVMLSEQEARASL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHCC
SPDVDLAAVNGPRSTVLAGTAEAIAELAARFDRSGIGRQDLKTSHAFHSFMMEPALEAFA
CCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QVLGTVTLNPPQIDIVSNLTGDWLTAQEATDPAYWVAHLRQTVLFGPCLARVLELPAPFL
HHHCCCCCCCCCEEHHHCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
LEVGPGSTLTRLARQQGKAQLRVATSLPDAKALLDACDHALLALAELWIAGIDVELVAEK
EEECCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
DAGPRRRVPLPTYPFQRSSYAIARIAPTESMPDEAARQPSIEDWLYQPVWQRAPIEHLTT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHC
SGHEHWLILGGEETVAAIGPVSDQIKVTRVRSGIAYENAGGTYHIDSADPQHYSAVLADL
CCCCEEEEECCCCCEEEECCCCCCEEEEEHHCCCEEECCCCEEEECCCCCHHHHHHHHHH
AANGATLTQIVNGFSLDANAAPDTAFASSFALAKALTTTESRPPLLTVLACGLHAVTGAE
HCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCH
VVDAQAAKVLGMLRVLSQEIPGISCRSIDFPSAEGAIVPGLAEALSRPWRDDRTVMALRN
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEEC
GYCWVESHVPTCLPEPADVPALTAGATYLIAGDLLDGLALVYARSLVQTLGAKVVLVGPS
CEEEEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GLPNAADWEHWLASHGPKHPVSALIRALRGIGTPGEDYVLFSGDLADPAWLATCLNSLGA
CCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
PFGPIRGAFQTAAMGEVYHCPLTEATVERNAALFATKVDGLNALSAALADHTPDFVLVQS
CCCHHHHHHHHHHCCCEEECCCCHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHH
SLSTLVGGAGLAAYAGANSFLDAFVDARRGAHRPVWQAIAWDTCLPFGTTREEATGFLND
HHHHHHCCCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AIDADEVWRATRAVLAQPQVSRLAVTPVDLRHRMAAARQEPRAGVAVDQQENIGRERVQA
CCCHHHHHHHHHHHHCCCCHHHEEECCHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHH
AFIAPRDPIETDVAAVIGELLGISRVGIDDNFFELGGHSLLAVQVVTRLRKQFSIELPMR
HCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCHH
ALLFDAPTVGGIAAVIRERLEAARKEQAELAALLDDIEAEALRKEA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2234082; 2024119; 1740151 [H]