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The map label for this gene is dppA [H]

Identifier: 222102575

GI number: 222102575

Start: 181186

End: 182781

Strand: Reverse

Name: dppA [H]

Synonym: Avi_7212

Alternate gene names: 222102575

Gene position: 182781-181186 (Counterclockwise)

Preceding gene: 222102576

Following gene: 222102570

Centisome position: 28.93

GC content: 55.14

Gene sequence:

>1596_bases
ATGACGCTCACCAGACGCGACTTTCACCGCATTGCCCTTGCCGCAGGGGCCTTCACGGCGCTGCCCGGCGGGGCCTTTGC
CGCCGCAGAAGAGCCAATTTCCGGCGGAACGCTGAAGATTGTTTATTTTCCCGAGCCAACCCAGTTGGTGGCCATCAACA
CCAGCTCGGGCGGTGCGCAATTCATCGGAGCCAAAATTTTCGATGGTTTGCTGACCTATGATTACGACCTGACGCCCAAA
CCAGCGCTGGCCAAGGAATGGAGCATTTCACCTGACGGTAAGACCTATATCTTCCATCTGCGCCCCAATGTAACCTTCCA
TGATGGCAAGCCGTTGACATCGGCGGATGTCGCCTTTTCGATTTTCCGCCTCAAGGAAGCCCATCCGCGGGGACGGGCTA
TTTTTGCCACCGTGGAAAGCATTGATACCAGCGATCCGCTGGTGGCAAAGCTCATCCTTTCCAAGCCGACGCCAGCGCTG
ATCACCGCCCTGTCTGGCTCTGAATCACCCATTGTGCCAAAGCACATTTTCGAGACCTTCAAGCCCACCGAAAATCCAAA
GCCGCAGCAGATTATTGGCAGCGGCCCCTTTGCGCTGAAGGAATGGGTGCCGGGCAGCCATATTCTGCTGGAACGCAATG
CTGCCCATTGGGATGCGCCAAGGCCCTATCTCGACCGCGTTATTCTGAGGCTGATCAATGATGCCAGCGCTCGCTCGGCA
GCCCTTGAAACCGGGGAGGCCGATATTGGTCCCAATCCGGTTCCGCTTTCTGATCTGGATCGGTTGAAAAGCGTTGCGAC
ACTCAAGGTCGATGATCAGATCTATGCCTATGCGGGCCAGCAGAACCAGTTGGTGATCAATCTGGAAAACAGCTACCTGA
AGGAGCAGAAAGTCCGCCAAGCCATTGCCCATGCCATCGATGTGAAGGCGCTGATCAACATCGTGCTCTATGGCTATGGC
ATCCCCTCACCCACGCCGATCAGCCCCGGTCTGGCGAAATTTCACAATCCCGATATTGGCTTTGCCAAATATGATGTGGC
CTTAGCCGAAAAACTGCTGGATGAAGCGGGCTTTCGCCGTCAAGCAAACGGCAAGCGTTTCAAGCTAAGGGTCACGACCA
ACCCGTTTAATCCGGCGAGCTATTCAGACTTTATCGCACAAGCGCTGATCAAGATCGGCATTGAGGCGGATATTCAAAAA
TTCGATTTCGGCACCTATGTCAAAGTGGTCTATACGGACCGCGCCTGGGATCTTTCGGTGGAATCGCTCTCCAACACATT
TGATCCCACCGCTGGCGTGCAGCGGGTCTATTGGAGCAAGAATTTCAAAATCGGCCTGCCCTTTTCCAACGCCAGCCACT
ACGAAAACCCGGAGGTGGACCGCCTGCTGGAAGCGGCTGCGGTGGAGCCGGACATTGAAAAACGCGCCCAATTGTTTAGG
GATTTTCAGGTGATCATCGCCCGCGATCTTCCCGTGATCAATCTCGTTTCCCCCATCCAACCCGTGGTGGGCAACAAGCG
CGTGCGCAATTACGCTTATGGCGCGGAAGGTCTGATTGGCAACCTTGCCTATGCCAGCCTTGCAAAAAACAGCTAA

Upstream 100 bases:

>100_bases
ATAGTGACACCCACTTTATTCAGGACACAAAACGCATTCTGACGCTGCTGGCGGAACGCCACGGCTTTCCGCAACTGCAC
TGACCGGAGGAGGCGAAGAC

Downstream 100 bases:

>100_bases
ACATTGAGCAGGCCCCGACAAAGGGGCCTGTTTTTTTGCCCATTATCATGGTTTCGCACTGTCTTCTCAAATAGCATTAC
AGCGCCAGAACCATTCAAGG

Product: ABC transporter substrate binding protein (oligopeptide)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTLTRRDFHRIALAAGAFTALPGGAFAAAEEPISGGTLKIVYFPEPTQLVAINTSSGGAQFIGAKIFDGLLTYDYDLTPK
PALAKEWSISPDGKTYIFHLRPNVTFHDGKPLTSADVAFSIFRLKEAHPRGRAIFATVESIDTSDPLVAKLILSKPTPAL
ITALSGSESPIVPKHIFETFKPTENPKPQQIIGSGPFALKEWVPGSHILLERNAAHWDAPRPYLDRVILRLINDASARSA
ALETGEADIGPNPVPLSDLDRLKSVATLKVDDQIYAYAGQQNQLVINLENSYLKEQKVRQAIAHAIDVKALINIVLYGYG
IPSPTPISPGLAKFHNPDIGFAKYDVALAEKLLDEAGFRRQANGKRFKLRVTTNPFNPASYSDFIAQALIKIGIEADIQK
FDFGTYVKVVYTDRAWDLSVESLSNTFDPTAGVQRVYWSKNFKIGLPFSNASHYENPEVDRLLEAAAVEPDIEKRAQLFR
DFQVIIARDLPVINLVSPIQPVVGNKRVRNYAYGAEGLIGNLAYASLAKNS

Sequences:

>Translated_531_residues
MTLTRRDFHRIALAAGAFTALPGGAFAAAEEPISGGTLKIVYFPEPTQLVAINTSSGGAQFIGAKIFDGLLTYDYDLTPK
PALAKEWSISPDGKTYIFHLRPNVTFHDGKPLTSADVAFSIFRLKEAHPRGRAIFATVESIDTSDPLVAKLILSKPTPAL
ITALSGSESPIVPKHIFETFKPTENPKPQQIIGSGPFALKEWVPGSHILLERNAAHWDAPRPYLDRVILRLINDASARSA
ALETGEADIGPNPVPLSDLDRLKSVATLKVDDQIYAYAGQQNQLVINLENSYLKEQKVRQAIAHAIDVKALINIVLYGYG
IPSPTPISPGLAKFHNPDIGFAKYDVALAEKLLDEAGFRRQANGKRFKLRVTTNPFNPASYSDFIAQALIKIGIEADIQK
FDFGTYVKVVYTDRAWDLSVESLSNTFDPTAGVQRVYWSKNFKIGLPFSNASHYENPEVDRLLEAAAVEPDIEKRAQLFR
DFQVIIARDLPVINLVSPIQPVVGNKRVRNYAYGAEGLIGNLAYASLAKNS
>Mature_530_residues
TLTRRDFHRIALAAGAFTALPGGAFAAAEEPISGGTLKIVYFPEPTQLVAINTSSGGAQFIGAKIFDGLLTYDYDLTPKP
ALAKEWSISPDGKTYIFHLRPNVTFHDGKPLTSADVAFSIFRLKEAHPRGRAIFATVESIDTSDPLVAKLILSKPTPALI
TALSGSESPIVPKHIFETFKPTENPKPQQIIGSGPFALKEWVPGSHILLERNAAHWDAPRPYLDRVILRLINDASARSAA
LETGEADIGPNPVPLSDLDRLKSVATLKVDDQIYAYAGQQNQLVINLENSYLKEQKVRQAIAHAIDVKALINIVLYGYGI
PSPTPISPGLAKFHNPDIGFAKYDVALAEKLLDEAGFRRQANGKRFKLRVTTNPFNPASYSDFIAQALIKIGIEADIQKF
DFGTYVKVVYTDRAWDLSVESLSNTFDPTAGVQRVYWSKNFKIGLPFSNASHYENPEVDRLLEAAAVEPDIEKRAQLFRD
FQVIIARDLPVINLVSPIQPVVGNKRVRNYAYGAEGLIGNLAYASLAKNS

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=500, Percent_Identity=25, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1787052, Length=510, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787762, Length=446, Percent_Identity=26.457399103139, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787495, Length=559, Percent_Identity=24.6869409660107, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1789397, Length=491, Percent_Identity=23.8289205702648, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787551, Length=505, Percent_Identity=22.7722772277228, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789887, Length=344, Percent_Identity=27.0348837209302, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87081878, Length=464, Percent_Identity=24.1379310344828, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58250; Mature: 58119

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRRDFHRIALAAGAFTALPGGAFAAAEEPISGGTLKIVYFPEPTQLVAINTSSGGAQ
CCCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCH
FIGAKIFDGLLTYDYDLTPKPALAKEWSISPDGKTYIFHLRPNVTFHDGKPLTSADVAFS
HHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHH
IFRLKEAHPRGRAIFATVESIDTSDPLVAKLILSKPTPALITALSGSESPIVPKHIFETF
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHC
KPTENPKPQQIIGSGPFALKEWVPGSHILLERNAAHWDAPRPYLDRVILRLINDASARSA
CCCCCCCCCCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHH
ALETGEADIGPNPVPLSDLDRLKSVATLKVDDQIYAYAGQQNQLVINLENSYLKEQKVRQ
HHCCCCCCCCCCCCCHHHHHHHHHEEEEEECCEEEEEECCCCEEEEEECHHHHHHHHHHH
AIAHAIDVKALINIVLYGYGIPSPTPISPGLAKFHNPDIGFAKYDVALAEKLLDEAGFRR
HHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QANGKRFKLRVTTNPFNPASYSDFIAQALIKIGIEADIQKFDFGTYVKVVYTDRAWDLSV
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEECCCCCCCH
ESLSNTFDPTAGVQRVYWSKNFKIGLPFSNASHYENPEVDRLLEAAAVEPDIEKRAQLFR
HHHHCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
DFQVIIARDLPVINLVSPIQPVVGNKRVRNYAYGAEGLIGNLAYASLAKNS
HHHHHHHCCCCCEEHHCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLTRRDFHRIALAAGAFTALPGGAFAAAEEPISGGTLKIVYFPEPTQLVAINTSSGGAQ
CCCHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCH
FIGAKIFDGLLTYDYDLTPKPALAKEWSISPDGKTYIFHLRPNVTFHDGKPLTSADVAFS
HHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEECCCCCCHHHHHHH
IFRLKEAHPRGRAIFATVESIDTSDPLVAKLILSKPTPALITALSGSESPIVPKHIFETF
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHC
KPTENPKPQQIIGSGPFALKEWVPGSHILLERNAAHWDAPRPYLDRVILRLINDASARSA
CCCCCCCCCCEECCCCCHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHHH
ALETGEADIGPNPVPLSDLDRLKSVATLKVDDQIYAYAGQQNQLVINLENSYLKEQKVRQ
HHCCCCCCCCCCCCCHHHHHHHHHEEEEEECCEEEEEECCCCEEEEEECHHHHHHHHHHH
AIAHAIDVKALINIVLYGYGIPSPTPISPGLAKFHNPDIGFAKYDVALAEKLLDEAGFRR
HHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCC
QANGKRFKLRVTTNPFNPASYSDFIAQALIKIGIEADIQKFDFGTYVKVVYTDRAWDLSV
CCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCEEEEEEECCCCCCCH
ESLSNTFDPTAGVQRVYWSKNFKIGLPFSNASHYENPEVDRLLEAAAVEPDIEKRAQLFR
HHHHCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
DFQVIIARDLPVINLVSPIQPVVGNKRVRNYAYGAEGLIGNLAYASLAKNS
HHHHHHHCCCCCEEHHCCHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]