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The map label for this gene is dppC [H]

Identifier: 222102568

GI number: 222102568

Start: 169766

End: 170638

Strand: Reverse

Name: dppC [H]

Synonym: Avi_7202

Alternate gene names: 222102568

Gene position: 170638-169766 (Counterclockwise)

Preceding gene: 222102569

Following gene: 222102567

Centisome position: 27.01

GC content: 59.91

Gene sequence:

>873_bases
ATGAGCCTTTCCTCCACACTGCTTGATCGCAACCTTGGCCGCACGAGTGATATTTTGCGCGGCATTCTCGCCCGTCCGGG
CTTGCTGATTGCAGCTCTGTTCGTGGTTCTCGTTGCTCTTTCCACCCTGTGGCCCGCGCTGCTCACATCGGCTGATCCTA
TCACTGCCGATCCCTTGCAAGCACAATTGCCACCCTCAGCAGACCATTGGTTTGGCACCGATCATCTGGGGCGGGATGTG
TTTTCCCGTGTGGTCTATGGCACGCGCTATTCCATTTTGATTGGCGTCAGCGCCATTACCATTGCTGCCGTGTTCGGCTC
TCTGCTCGGCTTGCTGGCCGGGCTGTCACGCGGGCTTGTGGATGAGTTCATCACCCGTTTTCTCGATGTGGTTTCGTCCT
TTCCCGATCTGCTGCTGGCGTTGGTGCTGATCTCCTTTACCGGCCCCGGCACGCTCAATCTTATTTTTGCGCTGGGCGTT
GCCTCCATTCCCCGCTTTGCCCGGGTGGTGCGCGCCCAAACCTTTGTGATTGCCCAAAGTGGCTATGTGGAACAGGCCAA
GACCTTTGGGCTGACCCGCCCTGTTCTGGTGTTTCGCCATGTGCTGCCCCATGCCATCGCGCAGGTGCCAATTCTGGCCA
CCATCGGCCTTGGCACTGCCATCATCAATGCGGCGGGCCTGAGTTTTCTCGGCATGGGTCCGCAGCCGCCAGCACCCGAA
TGGGGGGCGATGCTGGCCGATGCGCGCAATTATTTGCGCGTGGCGTGGTGGATTGGCGTGTGGCCGGGACTGGCCATTAC
CGCCACCGTGATTGCCATCAGCGTGCTGGGACGCCGCTGGCAGGCAGCATTTGAAGGCAGGAGACAGGCATGA

Upstream 100 bases:

>100_bases
TTCTCTCGGCCTTTGTCTATGTGGTGTTGAGCACGGCGGTGGATGTGCTCTATCTGCGGCTTGATCCACGGTTGCGAACG
AAGGCGCGGGAGGATGCGCG

Downstream 100 bases:

>100_bases
CCCCGCTGATCCAGATCCGCAATCTCACCATCGGCTTTCCAAAAGACGGGCGTGACCATAACGTTGTGCATGGCCTTGAT
CTGACAATCCATGCTGGGGA

Product: ABC transporter membrane spanning protein (dipeptide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSLSSTLLDRNLGRTSDILRGILARPGLLIAALFVVLVALSTLWPALLTSADPITADPLQAQLPPSADHWFGTDHLGRDV
FSRVVYGTRYSILIGVSAITIAAVFGSLLGLLAGLSRGLVDEFITRFLDVVSSFPDLLLALVLISFTGPGTLNLIFALGV
ASIPRFARVVRAQTFVIAQSGYVEQAKTFGLTRPVLVFRHVLPHAIAQVPILATIGLGTAIINAAGLSFLGMGPQPPAPE
WGAMLADARNYLRVAWWIGVWPGLAITATVIAISVLGRRWQAAFEGRRQA

Sequences:

>Translated_290_residues
MSLSSTLLDRNLGRTSDILRGILARPGLLIAALFVVLVALSTLWPALLTSADPITADPLQAQLPPSADHWFGTDHLGRDV
FSRVVYGTRYSILIGVSAITIAAVFGSLLGLLAGLSRGLVDEFITRFLDVVSSFPDLLLALVLISFTGPGTLNLIFALGV
ASIPRFARVVRAQTFVIAQSGYVEQAKTFGLTRPVLVFRHVLPHAIAQVPILATIGLGTAIINAAGLSFLGMGPQPPAPE
WGAMLADARNYLRVAWWIGVWPGLAITATVIAISVLGRRWQAAFEGRRQA
>Mature_289_residues
SLSSTLLDRNLGRTSDILRGILARPGLLIAALFVVLVALSTLWPALLTSADPITADPLQAQLPPSADHWFGTDHLGRDVF
SRVVYGTRYSILIGVSAITIAAVFGSLLGLLAGLSRGLVDEFITRFLDVVSSFPDLLLALVLISFTGPGTLNLIFALGVA
SIPRFARVVRAQTFVIAQSGYVEQAKTFGLTRPVLVFRHVLPHAIAQVPILATIGLGTAIINAAGLSFLGMGPQPPAPEW
GAMLADARNYLRVAWWIGVWPGLAITATVIAISVLGRRWQAAFEGRRQA

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=252, Percent_Identity=44.4444444444444, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI1787760, Length=252, Percent_Identity=40.4761904761905, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1789964, Length=222, Percent_Identity=39.6396396396396, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789889, Length=226, Percent_Identity=34.070796460177, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1787498, Length=263, Percent_Identity=32.319391634981, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787549, Length=222, Percent_Identity=35.5855855855856, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788505, Length=240, Percent_Identity=30, Blast_Score=102, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30954; Mature: 30823

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSTLLDRNLGRTSDILRGILARPGLLIAALFVVLVALSTLWPALLTSADPITADPLQ
CCCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AQLPPSADHWFGTDHLGRDVFSRVVYGTRYSILIGVSAITIAAVFGSLLGLLAGLSRGLV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEFITRFLDVVSSFPDLLLALVLISFTGPGTLNLIFALGVASIPRFARVVRAQTFVIAQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
GYVEQAKTFGLTRPVLVFRHVLPHAIAQVPILATIGLGTAIINAAGLSFLGMGPQPPAPE
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCH
WGAMLADARNYLRVAWWIGVWPGLAITATVIAISVLGRRWQAAFEGRRQA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLSSTLLDRNLGRTSDILRGILARPGLLIAALFVVLVALSTLWPALLTSADPITADPLQ
CCHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AQLPPSADHWFGTDHLGRDVFSRVVYGTRYSILIGVSAITIAAVFGSLLGLLAGLSRGLV
CCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEFITRFLDVVSSFPDLLLALVLISFTGPGTLNLIFALGVASIPRFARVVRAQTFVIAQS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
GYVEQAKTFGLTRPVLVFRHVLPHAIAQVPILATIGLGTAIINAAGLSFLGMGPQPPAPE
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCH
WGAMLADARNYLRVAWWIGVWPGLAITATVIAISVLGRRWQAAFEGRRQA
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]