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The map label for this gene is yajO [H]

Identifier: 222102554

GI number: 222102554

Start: 152887

End: 153936

Strand: Direct

Name: yajO [H]

Synonym: Avi_7188

Alternate gene names: 222102554

Gene position: 152887-153936 (Clockwise)

Preceding gene: 222102553

Following gene: 222102555

Centisome position: 24.2

GC content: 58.86

Gene sequence:

>1050_bases
ATGGTTGACTATCGTTATCTGGGACGCAGTGCGCTGAAAGTTTCACCCCTCAGCCTTGGCACGATGATGTTTGGCGGCCC
AACGCCGGATGAAGTGGCCTTTCGCATTATCGACAAGGCGCGCGAGCAGGGCATTAATTTCATTGATACGGCAGATGTCT
ATCACGATGGCAAATCCGAGGAAGTGGTCGGGCGTGGCATCAAGGCAAGCCGTGATCACTGGGTTTTGGCGACAAAATTT
GTCAATTCCCGCGAAAAAGGTCCCAATCTCGGCGGCCAGTCGCGCAAATGGGTGATCGAGACGGTGGAAAATTCGCTGCG
CCGCCTCAACACCGATTACATCGACATTCTCTATTTCCACCGTGCGGTGTTTGATGCCCCATTGGAAGAGCCGGTGCGCG
CCATTGCCGATCTGATCCGTGCAGGCAAGCTGCGCTATTTTGGCGTCTCGAATTTCCGTGGCTGGCGCATTGCAGAAATT
GCGCATCTGGCCGATCAGCTCGGCATTGATCGCCCCATTGCCAGCCAGCCGCTATACAATATCGTCAACCGCACCGCAGA
GGCTGAACAGCTTCCCGCCGCCCATCATTACGGGCTTGGTGTTGTGTCCTACTCGCCGCTGGCGCGTGGGGTTTTGACGG
GCAAATATGAGCCGGGCAAGGCACCCGCCGCCGATACCCGCGCAGGCCGTGGCGACAAGCGCATTCTGGAAACCGAATGG
CGGCCTGAATCGGTGGAGATCGCCCGCAAGGTGGCCGCCCACGCCCACGCCAAGGGCATTTCCGCTGCCGATTTCGCCCT
CGCTTGGGTGCTGAACAACCGCTACATCACCGCCGCCATTACTGGTCCTCGCACAGAGGAGCATTGGGATGGCTATATCC
GTGCTCTGGATGTGCGGCTGGATGCAGAGGATGAGGCGCTGGTCAACAGTCTGGTCGCTGAGGGGCATCCGTCTACGCCG
GGCTTTAATGACCCAAGCCACCCGGTTGAAGGCCGAGTGCCACGCTATAACGATCAGCCCTCGGTTAAGCCGGTTCGCGC
CGTTGCCTGA

Upstream 100 bases:

>100_bases
AGATCTCTGTCGTGAACAGGCACCGGATTATCAACTGTTTGGTCAAGCCCATGCCGTGGCCTGCCATCACGCCAACGAAC
ACTGAAATGGAGTAAGGACT

Downstream 100 bases:

>100_bases
TCATGGATGTGGCAGCCGGGGTGAAGATGAACACTCCGGCTGCCTGCTCAGTTTTGAAGGATGATGACCATGCCCCACAG
CGCGCGTGTTCCAGATAGCA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVDYRYLGRSALKVSPLSLGTMMFGGPTPDEVAFRIIDKAREQGINFIDTADVYHDGKSEEVVGRGIKASRDHWVLATKF
VNSREKGPNLGGQSRKWVIETVENSLRRLNTDYIDILYFHRAVFDAPLEEPVRAIADLIRAGKLRYFGVSNFRGWRIAEI
AHLADQLGIDRPIASQPLYNIVNRTAEAEQLPAAHHYGLGVVSYSPLARGVLTGKYEPGKAPAADTRAGRGDKRILETEW
RPESVEIARKVAAHAHAKGISAADFALAWVLNNRYITAAITGPRTEEHWDGYIRALDVRLDAEDEALVNSLVAEGHPSTP
GFNDPSHPVEGRVPRYNDQPSVKPVRAVA

Sequences:

>Translated_349_residues
MVDYRYLGRSALKVSPLSLGTMMFGGPTPDEVAFRIIDKAREQGINFIDTADVYHDGKSEEVVGRGIKASRDHWVLATKF
VNSREKGPNLGGQSRKWVIETVENSLRRLNTDYIDILYFHRAVFDAPLEEPVRAIADLIRAGKLRYFGVSNFRGWRIAEI
AHLADQLGIDRPIASQPLYNIVNRTAEAEQLPAAHHYGLGVVSYSPLARGVLTGKYEPGKAPAADTRAGRGDKRILETEW
RPESVEIARKVAAHAHAKGISAADFALAWVLNNRYITAAITGPRTEEHWDGYIRALDVRLDAEDEALVNSLVAEGHPSTP
GFNDPSHPVEGRVPRYNDQPSVKPVRAVA
>Mature_349_residues
MVDYRYLGRSALKVSPLSLGTMMFGGPTPDEVAFRIIDKAREQGINFIDTADVYHDGKSEEVVGRGIKASRDHWVLATKF
VNSREKGPNLGGQSRKWVIETVENSLRRLNTDYIDILYFHRAVFDAPLEEPVRAIADLIRAGKLRYFGVSNFRGWRIAEI
AHLADQLGIDRPIASQPLYNIVNRTAEAEQLPAAHHYGLGVVSYSPLARGVLTGKYEPGKAPAADTRAGRGDKRILETEW
RPESVEIARKVAAHAHAKGISAADFALAWVLNNRYITAAITGPRTEEHWDGYIRALDVRLDAEDEALVNSLVAEGHPSTP
GFNDPSHPVEGRVPRYNDQPSVKPVRAVA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=305, Percent_Identity=34.4262295081967, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI27436962, Length=303, Percent_Identity=34.6534653465347, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI27436969, Length=303, Percent_Identity=34.983498349835, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI4504825, Length=303, Percent_Identity=34.983498349835, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI27436966, Length=303, Percent_Identity=34.3234323432343, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=32.7974276527331, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI223718702, Length=336, Percent_Identity=30.0595238095238, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI41152114, Length=334, Percent_Identity=28.7425149700599, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI41327764, Length=336, Percent_Identity=28.5714285714286, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI223718708, Length=231, Percent_Identity=31.1688311688312, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI87081735, Length=312, Percent_Identity=36.8589743589744, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=30.6990881458967, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=31.6568047337278, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788070, Length=332, Percent_Identity=28.6144578313253, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788081, Length=268, Percent_Identity=32.4626865671642, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI212645785, Length=291, Percent_Identity=24.3986254295533, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=325, Percent_Identity=31.6923076923077, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=28.695652173913, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319951, Length=338, Percent_Identity=28.698224852071, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319958, Length=314, Percent_Identity=28.9808917197452, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322615, Length=267, Percent_Identity=27.7153558052434, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=35.2564102564103, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45549126, Length=319, Percent_Identity=26.0188087774295, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640980, Length=315, Percent_Identity=25.3968253968254, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646155, Length=322, Percent_Identity=27.9503105590062, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=28.0542986425339, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38649; Mature: 38649

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDYRYLGRSALKVSPLSLGTMMFGGPTPDEVAFRIIDKAREQGINFIDTADVYHDGKSE
CCCHHHHCCCCEEECCCEECCEECCCCCHHHHHHHHHHHHHHCCCCEEECHHHHCCCCCH
EVVGRGIKASRDHWVLATKFVNSREKGPNLGGQSRKWVIETVENSLRRLNTDYIDILYFH
HHHHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
RAVFDAPLEEPVRAIADLIRAGKLRYFGVSNFRGWRIAEIAHLADQLGIDRPIASQPLYN
HHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
IVNRTAEAEQLPAAHHYGLGVVSYSPLARGVLTGKYEPGKAPAADTRAGRGDKRILETEW
HHHCCHHHHHCCCHHHCCCEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCC
RPESVEIARKVAAHAHAKGISAADFALAWVLNNRYITAAITGPRTEEHWDGYIRALDVRL
CCHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCEEEEEECCCCCHHHHCCEEEEEEEEE
DAEDEALVNSLVAEGHPSTPGFNDPSHPVEGRVPRYNDQPSVKPVRAVA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure
MVDYRYLGRSALKVSPLSLGTMMFGGPTPDEVAFRIIDKAREQGINFIDTADVYHDGKSE
CCCHHHHCCCCEEECCCEECCEECCCCCHHHHHHHHHHHHHHCCCCEEECHHHHCCCCCH
EVVGRGIKASRDHWVLATKFVNSREKGPNLGGQSRKWVIETVENSLRRLNTDYIDILYFH
HHHHCCCCCCCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
RAVFDAPLEEPVRAIADLIRAGKLRYFGVSNFRGWRIAEIAHLADQLGIDRPIASQPLYN
HHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHH
IVNRTAEAEQLPAAHHYGLGVVSYSPLARGVLTGKYEPGKAPAADTRAGRGDKRILETEW
HHHCCHHHHHCCCHHHCCCEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCC
RPESVEIARKVAAHAHAKGISAADFALAWVLNNRYITAAITGPRTEEHWDGYIRALDVRL
CCHHHHHHHHHHHHHHHCCCCHHHHHEEEEECCCEEEEEECCCCCHHHHCCEEEEEEEEE
DAEDEALVNSLVAEGHPSTPGFNDPSHPVEGRVPRYNDQPSVKPVRAVA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]