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The map label for this gene is infB [H]

Identifier: 222097257

GI number: 222097257

Start: 3556808

End: 3558868

Strand: Reverse

Name: infB [H]

Synonym: BCQ_3597

Alternate gene names: 222097257

Gene position: 3558868-3556808 (Counterclockwise)

Preceding gene: 222097258

Following gene: 222097256

Centisome position: 68.25

GC content: 38.04

Gene sequence:

>2061_bases
ATGAGTAAAATTCGAGTGCATGAATATGCGAAAAAACATAATATCTCAAGTAAAGATCTTATGACAAAACTAAAAGAAAT
GAATATCGAGGTTTCGAATCATATGACAATGTTAGACGATGAAGTAGTAAACAAATTAGATAATGAGTATCAAGCTGAAA
AACCTTCTGTTGCAGATGAGTTTGAAGTAGAAGAAAAAGTTGTTCGTAGTAAAAAGAACAGCAATAAGAAAAAGAAAAAA
GGCAAAGGAAACGAAGATAAGCGTCAAGAGAACTTTGCTGGAAGACAACAAACACAAACTGTAGAAACACCAGATAAAAT
TACTTTCTCTGGAAGTCTTACAGTAGGTGATCTTGCTAAGAAATTAAGCAAAGAGCCATCTGAAATTATTAAAAAGCTCT
TCATGCTTGGAATTATGGCAACAATTAACCAAGATTTAGATAAAGATACAATTGAGTTAATTGCTAACGACTACGGTATT
GAAGTAGAAGAAGAAGTAATTGTAAGCGAAACTGAGTTTGAAACATTCATCGATGAGCAAGATGATGAAGAGAACTTAAA
AGAGCGTCCAGCTGTAGTTACAATCATGGGACACGTTGACCATGGTAAAACAACATTGCTTGACTCTATCCGTAACTCTA
AAGTAACTGCTGGTGAAGCGGGTGGAATTACTCAGCATATTGGTGCATACCAAGTTGAAGTAAATGACAAGAAAATTACA
TTCTTAGATACACCTGGTCACGCGGCGTTTACAACGATGCGTGCTCGTGGTGCACAAGTAACGGATATTACAATCCTTGT
TGTTGCAGCTGATGACGGTGTTATGCCACAAACAGTTGAAGCAATTAACCATGCGAAAGCAGCAGGAGTACCAATTATTG
TTGCTGTGAATAAAATGGATAAACCAGCTGCGAACCCTGATCGCGTAATGCAAGAACTAACAGAATATGAATTAGTTCCA
GAAGCATGGGGCGGAGACACAATTTTCGTACCAATTTCTGCGATTCAAGGCGAAGGAATTGACAACTTACTAGAAATGAT
TCTTCTTGTAAGTGAAGTAGAAGAGTATAAAGCAAATCCAAACCGCTATGCAACTGGTACTGTAATCGAAGCCCAGCTTG
ATAAAGGTAAAGGAACTATTGCGACATTACTTGTTCAAAACGGTACGCTTCGAGTAGGAGATCCAATCGTTGTTGGAACT
ACATTCGGTCGTGTTCGTGCAATGGTAAGTGATATTGGTCGTCGTGTAAAAGTTGCTGGTCCATCAACTCCTGTTGAAAT
TACAGGTTTAAATGAAGTACCACAAGCAGGAGATCGTTTCATGGCATTCGCTGATGAGAAGAAAGCTCGTCAAATCGGTG
AATCACGTGCACAAGAAGCGTTACTTGCTCAACGTGGTGAGAAATCTAAATTAAGCCTTGAAGATTTATTCCAACAAATC
CAAGAGGGCGATGTAAAAGAAATTAACTTAATTGTGAAAGCGGACGTACAAGGTTCTGTAGAAGCAATGGCAGCATCACT
TCGTAAAATTGATGTTGAAGGTGTTAAAGTTAAAATTATCCATACAGGCGTAGGTGCGATTACAGAATCTGATATCATTT
TAGCTTCTGCATCTAATGCAATTGTAATTGGATTTAACGTACGCCCAGATGTAAATGCGAAGCGTACAGCTGAATTAGAG
AACGTTGATATTCGTTTACACCGCATTATTTATAAAGTAATCGAAGAGATCGAAGCAGCGATGCAAGGTATGCTAGATCC
AGAATTTGAAGAAAAAGTAATCGGTCAAGCTGAAGTACGTCAAACGTTTAAAGTAACAAAAGTTGGAACAATCGCAGGTT
GTTACGTAACAGATGGTAAAATTACACGTGATAGCGGCGTGCGTATTATCCGTGATGGTGTGGTAATCTATGAAGGTCAA
CTTGATACGTTAAAACGTTTCAAAGACGACGTAAAAGAAGTTGCTCAAAACTATGAGTGTGGTATTACAATTGAGAAATA
CAACGATCTTAAAGAAGGGGACATCATTGAAGCGTACATTATGGAAGAAGTGAAGCGATGA

Upstream 100 bases:

>100_bases
GCGATTGGGAGAGATGAGCGAGTCGTTGTAGCTGTGTTAGATGAAGGCTTTGCGAAAAAGCTGCGTAGCATGCTCGATAC
AAATTACCGGGGGTGAAGGT

Downstream 100 bases:

>100_bases
TTATCGCTTCTCTCTCATTTGAGTGTATGATTTACGATGTGCATTCTTTAAAAGAGAAACGAGCAATTTTGCAACGGGTG
TTAACTCGTGTGAAACAGCG

Product: translation initiation factor if-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 685

Protein sequence:

>686_residues
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKK
GKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKIT
FLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVP
EAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
TFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELE
NVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQ
LDTLKRFKDDVKEVAQNYECGITIEKYNDLKEGDIIEAYIMEEVKR

Sequences:

>Translated_686_residues
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKK
GKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGI
EVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKIT
FLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVP
EAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGT
TFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELE
NVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQ
LDTLKRFKDDVKEVAQNYECGITIEKYNDLKEGDIIEAYIMEEVKR
>Mature_685_residues
SKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKG
KGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIE
VEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITF
LDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPE
AWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTT
FGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQIQ
EGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELEN
VDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQL
DTLKRFKDDVKEVAQNYECGITIEKYNDLKEGDIIEAYIMEEVKR

Specific function: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 7

COG id: COG0532

COG function: function code J; Translation initiation factor 2 (IF-2; GTPase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-2 family [H]

Homologues:

Organism=Homo sapiens, GI53729339, Length=651, Percent_Identity=36.2519201228879, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI53729337, Length=651, Percent_Identity=36.2519201228879, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI84043963, Length=463, Percent_Identity=26.3498920086393, Blast_Score=123, Evalue=7e-28,
Organism=Homo sapiens, GI157426893, Length=256, Percent_Identity=27.34375, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI34147630, Length=240, Percent_Identity=31.25, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI18390331, Length=142, Percent_Identity=31.6901408450704, Blast_Score=67, Evalue=8e-11,
Organism=Escherichia coli, GI1789559, Length=579, Percent_Identity=54.9222797927461, Blast_Score=613, Evalue=1e-176,
Organism=Escherichia coli, GI2367247, Length=213, Percent_Identity=31.924882629108, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788922, Length=233, Percent_Identity=30.0429184549356, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994988, Length=137, Percent_Identity=36.4963503649635, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790412, Length=234, Percent_Identity=32.9059829059829, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789737, Length=234, Percent_Identity=32.9059829059829, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994658, Length=539, Percent_Identity=37.291280148423, Blast_Score=329, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI212656558, Length=568, Percent_Identity=25.8802816901408, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17557151, Length=219, Percent_Identity=30.5936073059361, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556456, Length=253, Percent_Identity=31.2252964426877, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141371, Length=254, Percent_Identity=28.3464566929134, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324550, Length=614, Percent_Identity=36.9706840390879, Blast_Score=361, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6319282, Length=531, Percent_Identity=27.1186440677966, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324761, Length=258, Percent_Identity=31.0077519379845, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28572034, Length=650, Percent_Identity=36.7692307692308, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24656849, Length=456, Percent_Identity=27.6315789473684, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI160714833, Length=122, Percent_Identity=54.0983606557377, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI78706572, Length=224, Percent_Identity=28.125, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281363316, Length=263, Percent_Identity=30.7984790874525, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864358, Length=263, Percent_Identity=30.7984790874525, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137380, Length=272, Percent_Identity=28.3088235294118, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921738, Length=248, Percent_Identity=31.0483870967742, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19922690, Length=230, Percent_Identity=27.8260869565217, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: 1150 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006847
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000178
- InterPro:   IPR015760
- InterPro:   IPR023115
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2; PF11987 IF-2; PF04760 IF2_N [H]

EC number: NA

Molecular weight: Translated: 75727; Mature: 75596

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
CCCCCHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHHHHHHHHCHHHCCCCCCCCHH
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAK
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHH
KLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEECHHHHHHCCCC
DDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKIT
CCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCEEE
FLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
EEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCC
NRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTTFGRVRAMVSDIGRRVKVAG
CCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEECCHHHHHHHHHHHCCEEEECC
PSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
CCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
HCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEEEECCCCEECCCEEEEECCCE
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHH
QTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQLDTLKRFKDDVKEVAQNYEC
HHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCC
GITIEKYNDLKEGDIIEAYIMEEVKR
CEEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADE
CCCCHHHHHHHCCCCHHHHHHHHHHCCEEHHCCEEHHHHHHHHHHCHHHCCCCCCCCHH
FEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAK
HHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHH
KLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQ
HHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEECHHHHHHCCCC
DDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKIT
CCHHHHHHCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCEEE
FLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMD
EEECCCCHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECCC
KPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANP
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHCCCC
NRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTTFGRVRAMVSDIGRRVKVAG
CCEECCEEEEEEECCCCCEEEEEEEECCEEEECCEEEEECCHHHHHHHHHHHCCEEEECC
PSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQI
CCCCEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
QEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNA
HCCCCEEEEEEEEECCCCHHHHHHHHHHHEECCCEEEEEEEECCCCEECCCEEEEECCCE
IVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVR
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHH
QTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIYEGQLDTLKRFKDDVKEVAQNYEC
HHHEEEEECEEEEEEEECCEEECCCCCEEEECCEEEEECCHHHHHHHHHHHHHHHCCCCC
GITIEKYNDLKEGDIIEAYIMEEVKR
CEEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA