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The map label for this gene is cbaH [H]

Identifier: 222097213

GI number: 222097213

Start: 3505915

End: 3506901

Strand: Reverse

Name: cbaH [H]

Synonym: BCQ_3553

Alternate gene names: 222097213

Gene position: 3506901-3505915 (Counterclockwise)

Preceding gene: 222097214

Following gene: 222097211

Centisome position: 67.26

GC content: 37.89

Gene sequence:

>987_bases
ATGTGTACTAGTTTGACATTAGAGACAAAAAACGGTCAGCATCTTTTTGCAAGAACGATGGATTTCACATTAGATATGAA
TCAAGAAGTAATAATCATTCCTCGGCATTACCAGTGGAATAATATAACTGGTGAAATCATTAATACGAAACATGCTACGG
TCGGAATGGGAATTAATCATCAAGGAAGGATCATTATGGGGGACGGAGTAAATGAAGCAGGTATGACATGTGCAACACTC
TATTTTCCAGGATTCGCTACTTATAGTCAAAGCATAGATGACAATAAAACGAATTTAGCTCCATTTGATTTTGTAGCTTG
GAGTCTTACACAATTCAATTCTGTCAAAGAGTTAAAGAAATCTGTAGATAGCATTACCTTTTTGGATATACCGTTACCGG
ATTTAGGACTTACGCCACCGCTACATTGGATCTTAGCCGATAAATGGGGAGATTGCATTGTACTGGAGCCGACAAATGAA
GGATTAAAGATGTATGATAACCCACTAGGAGTGATGACGAATAGTCCGGAGTTTAATTGGCATTTGCAAAATTTAAGACA
ATATATTGGCCTTAAATCGCAGCCATTCGCGCCAACAGAATGGAGTAATTTACCATTAAGTGCTTTTGGCCAGGGCTCAG
GCTCAATGGGACTTCCAGGGGATTTCACCCCGCCATCGAGGTTTGTGCGGGCAGCATATGGCAAACAAAACATTCAAGGT
ATAGATAGTGAAGAAGAGGGAGTATCCGCCCTTTTTCATATCTTATCAAATTGCGAGGTACCTAAAGGCGGAGTAATAAC
AGAAGAAGGTGCATTAGATAATACCATATATACAAGCGTAATGTGTATGGAGTCCGGAACATATTATTATCATACTTACG
ATTGTAGACAAATTATAGCTGTTCATTTATTTCATGAAAATTTAGATACAGATGAGATTAAAGCCTATCCGTTCCAACGG
AAACAAAAAATATTTTATGAAAACTAA

Upstream 100 bases:

>100_bases
TGTACGTTCTTAATTTGTTTGTAAGGAAAGAGGTTTTTAATTTACAGACTTATCAGAATTATGTAAAGTGTAGATAAAAC
CATAAAATGGGGTGTTCTTT

Downstream 100 bases:

>100_bases
GTAGCTTTGAAACAATGTTTGGTGCATTTTTGAATATATATAATAGAGCAATAATGGTTTATATCATTCTTGGATGCTTC
TTTAACTTTGGGATTTATCA

Product: choloylglycine hydrolase

Products: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate; glycine

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MCTSLTLETKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMGDGVNEAGMTCATL
YFPGFATYSQSIDDNKTNLAPFDFVAWSLTQFNSVKELKKSVDSITFLDIPLPDLGLTPPLHWILADKWGDCIVLEPTNE
GLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLPLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQNIQG
IDSEEEGVSALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAVHLFHENLDTDEIKAYPFQR
KQKIFYEN

Sequences:

>Translated_328_residues
MCTSLTLETKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMGDGVNEAGMTCATL
YFPGFATYSQSIDDNKTNLAPFDFVAWSLTQFNSVKELKKSVDSITFLDIPLPDLGLTPPLHWILADKWGDCIVLEPTNE
GLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLPLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQNIQG
IDSEEEGVSALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAVHLFHENLDTDEIKAYPFQR
KQKIFYEN
>Mature_328_residues
MCTSLTLETKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINHQGRIIMGDGVNEAGMTCATL
YFPGFATYSQSIDDNKTNLAPFDFVAWSLTQFNSVKELKKSVDSITFLDIPLPDLGLTPPLHWILADKWGDCIVLEPTNE
GLKMYDNPLGVMTNSPEFNWHLQNLRQYIGLKSQPFAPTEWSNLPLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQNIQG
IDSEEEGVSALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIAVHLFHENLDTDEIKAYPFQR
KQKIFYEN

Specific function: Unknown

COG id: COG3049

COG function: function code M; Penicillin V acylase and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C59 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003199 [H]

Pfam domain/function: PF02275 CBAH [H]

EC number: 3.5.1.24

Molecular weight: Translated: 36902; Mature: 36902

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTSLTLETKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINH
CCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEECEEECCCCCEEEEECCCEEEECCCCC
QGRIIMGDGVNEAGMTCATLYFPGFATYSQSIDDNKTNLAPFDFVAWSLTQFNSVKELKK
CCCEEECCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVDSITFLDIPLPDLGLTPPLHWILADKWGDCIVLEPTNEGLKMYDNPLGVMTNSPEFNW
HHCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCCCEEECCCCCCE
HLQNLRQYIGLKSQPFAPTEWSNLPLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQNIQG
EHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
IDSEEEGVSALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIA
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHEEEEEEEECCEEEEEEECHHHHHH
VHLFHENLDTDEIKAYPFQRKQKIFYEN
HHHHHCCCCCCCEEECCCCHHCCCCCCC
>Mature Secondary Structure
MCTSLTLETKNGQHLFARTMDFTLDMNQEVIIIPRHYQWNNITGEIINTKHATVGMGINH
CCCEEEEECCCCCEEEEEEEEEEEECCCCEEEEECEEECCCCCEEEEECCCEEEECCCCC
QGRIIMGDGVNEAGMTCATLYFPGFATYSQSIDDNKTNLAPFDFVAWSLTQFNSVKELKK
CCCEEECCCCCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVDSITFLDIPLPDLGLTPPLHWILADKWGDCIVLEPTNEGLKMYDNPLGVMTNSPEFNW
HHCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECCCCCCCEEECCCCCEEECCCCCCE
HLQNLRQYIGLKSQPFAPTEWSNLPLSAFGQGSGSMGLPGDFTPPSRFVRAAYGKQNIQG
EHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCC
IDSEEEGVSALFHILSNCEVPKGGVITEEGALDNTIYTSVMCMESGTYYYHTYDCRQIIA
CCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHEEEEEEEECCEEEEEEECHHHHHH
VHLFHENLDTDEIKAYPFQRKQKIFYEN
HHHHHCCCCCCCEEECCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine; H2O

Specific reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine + H2O = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanate + glycine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8867804; 9384377 [H]