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The map label for this gene is cidA2 [H]

Identifier: 222097203

GI number: 222097203

Start: 3494509

End: 3494697

Strand: Reverse

Name: cidA2 [H]

Synonym: BCQ_3543

Alternate gene names: 222097203

Gene position: 3494697-3494509 (Counterclockwise)

Preceding gene: 222097204

Following gene: 222097202

Centisome position: 67.02

GC content: 34.39

Gene sequence:

>189_bases
GTGGATGGAGTATTCCATTTATCAATGCTAGGAAGTTTAATAGGGATGTTAATGCTGTTTCTGCTCCTTTCCACTCGTAT
TTTACCATTAAAGTGGTTTGAAGAAGCGACAATCGGTTCGGTGACTATGATTGTAACAGGAATACTCATCAGTATATTTA
TACCATATGGAACGAAATTTATATTTTAA

Upstream 100 bases:

>100_bases
CATAATAGAGAGGCGTAATATTGGAATGAGGGAAAGAAATGAAGTACGTGATGCTTTTACTTCAAGTAGGCGTGCTGTAT
GTATTTAGTTTAGTTGGTAC

Downstream 100 bases:

>100_bases
ATTGTAATGGAGATGATGAAAGTGACAACATGGTTTATAGTTACATTATTTATTTTTGGTGCCCTTAAAGTACTCGTTTC
TAGTATGCCAACTTCAGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 62; Mature: 62

Protein sequence:

>62_residues
MDGVFHLSMLGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGTKFIF

Sequences:

>Translated_62_residues
MDGVFHLSMLGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGTKFIF
>Mature_62_residues
MDGVFHLSMLGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGTKFIF

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 6939; Mature: 6939

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
8.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVFHLSMLGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGTKF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEE
IF
CC
>Mature Secondary Structure
MDGVFHLSMLGSLIGMLMLFLLLSTRILPLKWFEEATIGSVTMIVTGILISIFIPYGTKF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEE
IF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]