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The map label for this gene is ccdA [H]

Identifier: 222097125

GI number: 222097125

Start: 3418716

End: 3419423

Strand: Reverse

Name: ccdA [H]

Synonym: BCQ_3465

Alternate gene names: 222097125

Gene position: 3419423-3418716 (Counterclockwise)

Preceding gene: 222097128

Following gene: 222097124

Centisome position: 65.58

GC content: 34.32

Gene sequence:

>708_bases
ATGCAAGATATTAGTATTTTTTTAGCGTTTGGTGCTGGTTTTTTATCATTTATTTCCCCATGTTGCTTACCGCTTTATCC
GGCATTTTTATCGTACATAACAGGTATGTCGGTTTCTGAGTTGAAAGAAGAAAATGCAATGCTTCGCAAAAGAAGTATGA
TACATACAGCGTTTTTCTTACTTGGATTTTCAATTATATTTATTGCAATTGGATTTGGTACAAGCTTTATCGGGGGCATT
TTTACGAATTATAAAGATTTAATTAGACAGTTAGGTGGTATATTTATCATCGTGTTCGGTTTAATTATTGTCGGTGTATT
TAAGCCGAAGTTTTTAATGCAAGACCGTAAATTTACATTTAAGAATCGTCCGAGTGGTTATTTTGGATCAGTATTAATTG
GATTGGCGTTTGCCGCAGGATGGACTCCTTGTACTGGGCCTATTTTAGTGTCTGTCATTGGATTAGCAGCAACGAACCCA
GAGTCTGCGATGATTTATATGATCGCATATATACTTGGATTCGCTATCCCGTTCTTCGTACTATCATTCTTTATTACGAA
AATGTCTTGGATTAAAAGAAATAGTATGAAGTTCATGAAAATCGGGGGATACGTTATGATTATCATGGGTATTTTCTTAT
ACTTTAACTGGATGACGAAAATTATCGTATATTTCTCAAGTTTATTTGGTGGTTTTAAGGGTTTTTAG

Upstream 100 bases:

>100_bases
GGTAGTTTTTCTTATTATCACGTTGGAAAAGTGATTTCACGAATTGTTCATAGTATTTTTATATGTTTTTGCTACAATAT
GTAAGGAGAGGAGTGGAATA

Downstream 100 bases:

>100_bases
TATTATTCTGTGAAAATGTTGGAAATACTAACGGAAAAGCATATAATGAAAGTATATTTTGCATATAGCCACAAAAAAGG
ATGAGAAAATATGAACATAG

Product: cytochrome c-type biogenesis protein (holocytochrome-c synthase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFKGF

Sequences:

>Translated_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFKGF
>Mature_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFKGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26304; Mature: 26304

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFKGF
HHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFKGF
HHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]