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The map label for this gene is sigW [H]

Identifier: 222097044

GI number: 222097044

Start: 3334043

End: 3334552

Strand: Reverse

Name: sigW [H]

Synonym: BCQ_3384

Alternate gene names: 222097044

Gene position: 3334552-3334043 (Counterclockwise)

Preceding gene: 222097045

Following gene: 222097043

Centisome position: 63.95

GC content: 31.76

Gene sequence:

>510_bases
ATGATTGTAAAAGAAGAAACCGATGTTTCTTTAGCGAAAAAAGGTGATCATGAAGCATTTATGAGGCTTATACATACAGA
AAAAGTAAAGATGTATCGTATTGCAAAGGCTATGTTACGTGATGAGACAAATATAGAGGATGCGATACAAACAACAATTT
TAAAAGCCTATGAAAATATAAAAAAATTAAAGAAAGAAGAGTTTTTTCAAACTTGGTTGATTCGAATTTTAATGAATGAA
TGTAATAACATTATTAGAACGTATAAAAAGATAATTGTGACAGAAGAGAATGATTACAATATGAGTGCGTGCGATCAGTA
TGAAGATATAGATTTGTGTAATGCGATTCAATCGTTACATGAAGAGTTAAGAGCTGTTACGGTGCTTTATTATTATGAAG
ATATGAATCAAGAGAGTATAGCGAAGCTTTTAGAAGTACCAAAAGGAACAGTGAAATCGAGATTGGCACGTGCGAGGGAA
CAACTACAGAAACGATTAAAGATGGAATAG

Upstream 100 bases:

>100_bases
GAACCTTTTTCTAGGCTCATCCGTCTAATACATGTAAAGTTAAATTTGAAGTGAGGATGAAACAGGAGGAGCAATTGTGA
AAGTAATCCCTTTATATAAA

Downstream 100 bases:

>100_bases
GGGGTGCAAAGGATGGATAATGAAAAAATATTTGATGAGAAATTAAAAAAGAGAATAAAAGAAGAGAGTGTTATAGTGCC
ACCAGAGTTAAATGAAAAGA

Product: RNA polymerase sigma-70 factor, ecf subfamily

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MIVKEETDVSLAKKGDHEAFMRLIHTEKVKMYRIAKAMLRDETNIEDAIQTTILKAYENIKKLKKEEFFQTWLIRILMNE
CNNIIRTYKKIIVTEENDYNMSACDQYEDIDLCNAIQSLHEELRAVTVLYYYEDMNQESIAKLLEVPKGTVKSRLARARE
QLQKRLKME

Sequences:

>Translated_169_residues
MIVKEETDVSLAKKGDHEAFMRLIHTEKVKMYRIAKAMLRDETNIEDAIQTTILKAYENIKKLKKEEFFQTWLIRILMNE
CNNIIRTYKKIIVTEENDYNMSACDQYEDIDLCNAIQSLHEELRAVTVLYYYEDMNQESIAKLLEVPKGTVKSRLARARE
QLQKRLKME
>Mature_169_residues
MIVKEETDVSLAKKGDHEAFMRLIHTEKVKMYRIAKAMLRDETNIEDAIQTTILKAYENIKKLKKEEFFQTWLIRILMNE
CNNIIRTYKKIIVTEENDYNMSACDQYEDIDLCNAIQSLHEELRAVTVLYYYEDMNQESIAKLLEVPKGTVKSRLARARE
QLQKRLKME

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=173, Percent_Identity=24.8554913294798, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20058; Mature: 20058

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKEETDVSLAKKGDHEAFMRLIHTEKVKMYRIAKAMLRDETNIEDAIQTTILKAYENI
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKLKKEEFFQTWLIRILMNECNNIIRTYKKIIVTEENDYNMSACDQYEDIDLCNAIQSLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHH
EELRAVTVLYYYEDMNQESIAKLLEVPKGTVKSRLARAREQLQKRLKME
HHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVKEETDVSLAKKGDHEAFMRLIHTEKVKMYRIAKAMLRDETNIEDAIQTTILKAYENI
CCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KKLKKEEFFQTWLIRILMNECNNIIRTYKKIIVTEENDYNMSACDQYEDIDLCNAIQSLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHH
EELRAVTVLYYYEDMNQESIAKLLEVPKGTVKSRLARAREQLQKRLKME
HHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]