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The map label for this gene is moeB [H]

Identifier: 222097021

GI number: 222097021

Start: 3304160

End: 3305176

Strand: Reverse

Name: moeB [H]

Synonym: BCQ_3361

Alternate gene names: 222097021

Gene position: 3305176-3304160 (Counterclockwise)

Preceding gene: 222097022

Following gene: 222097020

Centisome position: 63.39

GC content: 36.28

Gene sequence:

>1017_bases
ATGGCTGAGCGGTATTCACGACAACATTTGTTTAAATCAATTGGGAGTAGAGGGCAAGAAAAAATTCGAAATAAACATGT
GTTAATTGTAGGAGTAGGCGCATTAGGAAGTGCAAGTGCCGAAAGTTTCGTACGTGCAGGTATTGGCAAGTTGACGATCA
TAGATCGTGATTACGTTGAATGGAGTAATTTACAAAGGCAACAATTGTACTCTGAACAAGATGCAAGAGAGAAATTGCCA
AAAGCAATCGCTGCTAAAAATCGGCTAGAAAAACTTAATTCGGAAGTACAAATACATGCTTTCGTAATGGATGCGTGTGT
AGAAAACTTGGAAGGGCTATTAGAAAATGTCGATGTAATCATTGATGCAACAGATAATTTCGATATCCGATTTATAATAA
ATGACTTATCACAAAAACATAATATCCCGTGGGTATATGGTTCTTGCGTTGGCTCGTACGGTATGAGTTGTACAATTATT
CCGCAAGAGACACCTTGTTTACATTGTGTGCTGAAGAACGTTCCAGTTACAGGTGTGACGTGTGATACAGCTGGAATTAT
TAGCCCGACTGTACAAATCGTCGCAGCATATCAAGTGGCGGAAGCACTCAAAATTTTAGTAGAAGATTTTGCAGCAATTA
GAAAAACATTTTTCATATTTGATATATGGAGTAATCAAAACCATTTTATAAAACTAGGGAAAATCAAGACAGACAATTGC
TCTTCATGCGGTTTGAATCGCATTTATCCTTATTTATTATACGAAAATCAAACGAAGGTAGCTGCTTTATGCGGAAGAAA
TACAGTTCAAATTAGACCAGTAGACAATAGAAAATACAATTTTGATGATATAGAAAAAGTATTAAAAAAAGTGGGGGAAG
TAAATCGGAATCCGTATTTACTATCTTGCCAATTAGATGAGTACCGCATCGTTGTTTTTCGGGATGGTCGTGTTTTTATT
CATGGCACAAATGATATTTCGAAAGCGAAACAACTATATTATTGCGTATTCGGCTAA

Upstream 100 bases:

>100_bases
TGTAATTGGCGGGGCTGGTTTTGTTGGATTTGCGTACTTTGCTTGTTATCAAAAACAACATTCTAATATGAAATAGAGTT
CGTGAGAGGAAGGGTATGTA

Downstream 100 bases:

>100_bases
TAGAAAGGGTTGTCAACAATGGAAAGAAGAGTACCAATCACAGTTGAAGAGGCTGTTCGTAAAGTGATGGGATTTGCTCA
TAACGGCTTAAAGGAGCTAC

Product: thiamine/molybdopterin biosynthesis moeb-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MAERYSRQHLFKSIGSRGQEKIRNKHVLIVGVGALGSASAESFVRAGIGKLTIIDRDYVEWSNLQRQQLYSEQDAREKLP
KAIAAKNRLEKLNSEVQIHAFVMDACVENLEGLLENVDVIIDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSCTII
PQETPCLHCVLKNVPVTGVTCDTAGIISPTVQIVAAYQVAEALKILVEDFAAIRKTFFIFDIWSNQNHFIKLGKIKTDNC
SSCGLNRIYPYLLYENQTKVAALCGRNTVQIRPVDNRKYNFDDIEKVLKKVGEVNRNPYLLSCQLDEYRIVVFRDGRVFI
HGTNDISKAKQLYYCVFG

Sequences:

>Translated_338_residues
MAERYSRQHLFKSIGSRGQEKIRNKHVLIVGVGALGSASAESFVRAGIGKLTIIDRDYVEWSNLQRQQLYSEQDAREKLP
KAIAAKNRLEKLNSEVQIHAFVMDACVENLEGLLENVDVIIDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSCTII
PQETPCLHCVLKNVPVTGVTCDTAGIISPTVQIVAAYQVAEALKILVEDFAAIRKTFFIFDIWSNQNHFIKLGKIKTDNC
SSCGLNRIYPYLLYENQTKVAALCGRNTVQIRPVDNRKYNFDDIEKVLKKVGEVNRNPYLLSCQLDEYRIVVFRDGRVFI
HGTNDISKAKQLYYCVFG
>Mature_337_residues
AERYSRQHLFKSIGSRGQEKIRNKHVLIVGVGALGSASAESFVRAGIGKLTIIDRDYVEWSNLQRQQLYSEQDAREKLPK
AIAAKNRLEKLNSEVQIHAFVMDACVENLEGLLENVDVIIDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSCTIIP
QETPCLHCVLKNVPVTGVTCDTAGIISPTVQIVAAYQVAEALKILVEDFAAIRKTFFIFDIWSNQNHFIKLGKIKTDNCS
SCGLNRIYPYLLYENQTKVAALCGRNTVQIRPVDNRKYNFDDIEKVLKKVGEVNRNPYLLSCQLDEYRIVVFRDGRVFIH
GTNDISKAKQLYYCVFG

Specific function: Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS [H]

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=244, Percent_Identity=29.9180327868852, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI38045948, Length=160, Percent_Identity=30.625, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI13376212, Length=227, Percent_Identity=32.5991189427313, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787048, Length=245, Percent_Identity=31.4285714285714, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082356, Length=250, Percent_Identity=33.6, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17540406, Length=248, Percent_Identity=32.258064516129, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321903, Length=254, Percent_Identity=26.7716535433071, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320598, Length=170, Percent_Identity=31.1764705882353, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24582879, Length=279, Percent_Identity=31.5412186379928, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28573937, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24641311, Length=210, Percent_Identity=31.9047619047619, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 38239; Mature: 38108

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERYSRQHLFKSIGSRGQEKIRNKHVLIVGVGALGSASAESFVRAGIGKLTIIDRDYVE
CCCHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHH
WSNLQRQQLYSEQDAREKLPKAIAAKNRLEKLNSEVQIHAFVMDACVENLEGLLENVDVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEE
IDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSCTIIPQETPCLHCVLKNVPVTGVT
EECCCCCEEEEEEEHHHHHCCCCEEEHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEE
CDTAGIISPTVQIVAAYQVAEALKILVEDFAAIRKTFFIFDIWSNQNHFIKLGKIKTDNC
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEECCCC
SSCGLNRIYPYLLYENQTKVAALCGRNTVQIRPVDNRKYNFDDIEKVLKKVGEVNRNPYL
CCCCCCCCCEEEEECCCCCEEHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEE
LSCQLDEYRIVVFRDGRVFIHGTNDISKAKQLYYCVFG
EEEEECCEEEEEEECCEEEEECCCCHHHHCEEEEEEEC
>Mature Secondary Structure 
AERYSRQHLFKSIGSRGQEKIRNKHVLIVGVGALGSASAESFVRAGIGKLTIIDRDYVE
CCHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCCCCCHHHHHHHCCCCEEEEEECCHHH
WSNLQRQQLYSEQDAREKLPKAIAAKNRLEKLNSEVQIHAFVMDACVENLEGLLENVDVI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCEEE
IDATDNFDIRFIINDLSQKHNIPWVYGSCVGSYGMSCTIIPQETPCLHCVLKNVPVTGVT
EECCCCCEEEEEEEHHHHHCCCCEEEHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEE
CDTAGIISPTVQIVAAYQVAEALKILVEDFAAIRKTFFIFDIWSNQNHFIKLGKIKTDNC
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCEEEEEEEECCCC
SSCGLNRIYPYLLYENQTKVAALCGRNTVQIRPVDNRKYNFDDIEKVLKKVGEVNRNPYL
CCCCCCCCCEEEEECCCCCEEHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEE
LSCQLDEYRIVVFRDGRVFIHGTNDISKAKQLYYCVFG
EEEEECCEEEEEEECCEEEEECCCCHHHHCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]