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The map label for this gene is zwf [H]

Identifier: 222096848

GI number: 222096848

Start: 3140308

End: 3141783

Strand: Reverse

Name: zwf [H]

Synonym: BCQ_3188

Alternate gene names: 222096848

Gene position: 3141783-3140308 (Counterclockwise)

Preceding gene: 222096849

Following gene: 222096847

Centisome position: 60.25

GC content: 37.94

Gene sequence:

>1476_bases
ATGACCTTTGTTTTATTTGGAGCGACAGGGGACCTAGCGAAACGCAAAATTTACCCCGCACTATATAACTTATATAGAGA
TCAAAAGCTTCCAAAGCAAATATCCGTTATCGGGCTTGGGAGACGTGAAGTATCTCATGTAGATTTTCAAAAAAGAATAA
AAGAATCAATAGAGACGTTTTCTCGTCATAGAGAAGAAGGTACTCCAGAACTCGAAGGTTTTTTAGATAATTTTCGCTAT
TGTCCATTAGATGTGAGTAAGCCGGAAGACTATGAGAGATTATTACAAGTCGTTCGTGAAAGGGAAGAAGAACTACATAT
AAAAGGGAATAGAATGTTCTATCTTTCCGTTGCTCCTGAATTTTTTGAGACAATCGCTTTAAATATTAAGGAAAGCGGAC
TTGATAAAACGGATGGATGGAAACGCCTAATGATTGAGAAACCGTTCGGACACGACCTTACATCTGCTCGTGAGCTGAAT
GATAAGCTTAGTCGCACGTTTGAAGAAGACGAGATATACCGTATTGATCATTATTTAGGTAAGCCGATGATTCAAAACCT
TGAAGCACTAGAGTTTGCAAATCCTGTTTTACAATCGATTTGGAATAAAGAACATATAGCGAATGTACAAATCACAGCGA
GTGAAACAGTTGGGGTTGAAGAAAGGGCAGGATATTATGATCAGGCAGGAGCCATTCGAGATATGGTTCAAAATCATATG
TTACAAATATTAATGATGACTGCTATGAATTTGCCGGAAAAGGTTAATGCATGTGAAATTCGAGAGGAAAAGCGAAAGGT
AATGGAGGCGCTTCGTAAAGTGAAAAAAGAAGACGTTCAAAACCATATCATTCGCGGACAATATGGTGCAGGTGAGATAA
ATGGCGGGCAAGTTGTAGCATATAAAGAGGAGCCAGGAGTAAATCCTTCTTCTAATATAGACACATTTGTCGCTGCTCGC
TTGTGGATCGATAATCCATTTTGGACTGGCGTTCCCTTTTATATACGAACAGGCAAACGAATGAAAGAAAAGTCTACTCG
TATTGTAATCGAATTTAAAAATACGTTAAAACAGCAATATCAAGATAGTAATCCAAATGCAGCACCTAACTTGTTAATAA
TTGAAATTAGCCCAGGTGAGAACGTTTCATTACAGTTAAATAGTAAAAATCCATTGAAAAATGGAGAAATTGAACCGATC
CGTATTAACTTTACTTGTGAGCAAGCGGATGTGGGAGTACCTGAAGCGTATGAAAGACTCATTCACGATGCTGTGAGTGG
AGACGCTACATTCTTTGCACATTGGAGAGAAGTTGAATTGTCATGGGAATGGGTACAACCAATTCTTGAAGCATTCGAGG
AAAACTTATTACCACTTCATGAATATGAGTCTGGTTCATATGGTCCAGAGGCATCTAATGAATTATTGCAAGAAAGTGGA
TTTAAATGGTGGTTAGATCAAGAAACGAAAAAATAA

Upstream 100 bases:

>100_bases
ATAACTCTTTGTTTTTTATAAAAACATGAGCTTCTGTACAATTCATTTTTAATATATTGACCAGGATTATACAACAAGAG
GGGGACTGAAATTGGAATCA

Downstream 100 bases:

>100_bases
GTACTTTCTTTCATGAAAGCATGTAGGGGGACGATTACTATGACACAAAACATAAATCAATTAGCAGTGAATACAATTCG
TACGTTATCAATTGATGCTA

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD; Vegetative protein 11; VEG11 [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESIETFSRHREEGTPELEGFLDNFRY
CPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELN
DKLSRTFEEDEIYRIDHYLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHM
LQILMMTAMNLPEKVNACEIREEKRKVMEALRKVKKEDVQNHIIRGQYGAGEINGGQVVAYKEEPGVNPSSNIDTFVAAR
LWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPI
RINFTCEQADVGVPEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESG
FKWWLDQETKK

Sequences:

>Translated_491_residues
MTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESIETFSRHREEGTPELEGFLDNFRY
CPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELN
DKLSRTFEEDEIYRIDHYLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHM
LQILMMTAMNLPEKVNACEIREEKRKVMEALRKVKKEDVQNHIIRGQYGAGEINGGQVVAYKEEPGVNPSSNIDTFVAAR
LWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPI
RINFTCEQADVGVPEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESG
FKWWLDQETKK
>Mature_490_residues
TFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESIETFSRHREEGTPELEGFLDNFRYC
PLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELND
KLSRTFEEDEIYRIDHYLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHML
QILMMTAMNLPEKVNACEIREEKRKVMEALRKVKKEDVQNHIIRGQYGAGEINGGQVVAYKEEPGVNPSSNIDTFVAARL
WIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPIR
INFTCEQADVGVPEAYERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESGF
KWWLDQETKK

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI109389365, Length=487, Percent_Identity=35.7289527720739, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI108773793, Length=487, Percent_Identity=35.7289527720739, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI52145310, Length=479, Percent_Identity=29.8538622129436, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1788158, Length=491, Percent_Identity=37.2708757637475, Blast_Score=333, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17538218, Length=485, Percent_Identity=36.9072164948454, Blast_Score=327, Evalue=7e-90,
Organism=Saccharomyces cerevisiae, GI6324088, Length=482, Percent_Identity=36.0995850622407, Blast_Score=292, Evalue=8e-80,
Organism=Drosophila melanogaster, GI24643350, Length=487, Percent_Identity=37.3716632443532, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24643352, Length=487, Percent_Identity=37.3716632443532, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI221513548, Length=495, Percent_Identity=29.4949494949495, Blast_Score=212, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 56777; Mature: 56646

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESIETF
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
SRHREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPE
HHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEEECHH
FFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDHYLG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHC
KPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHM
CHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
LQILMMTAMNLPEKVNACEIREEKRKVMEALRKVKKEDVQNHIIRGQYGAGEINGGQVVA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
YKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQY
ECCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCEEECCCHHHCCCCEEEEEEHHHHHHHH
QDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPIRINFTCEQADVGVPEAYERL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
IHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESG
HHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
FKWWLDQETKK
CEEECCCCCCC
>Mature Secondary Structure 
TFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRREVSHVDFQKRIKESIETF
EEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
SRHREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPE
HHHHHCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCEEEEEEECHH
FFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDHYLG
HHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHC
KPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHM
CHHHHHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
LQILMMTAMNLPEKVNACEIREEKRKVMEALRKVKKEDVQNHIIRGQYGAGEINGGQVVA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEE
YKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQY
ECCCCCCCCCCCCHHHHEEEEEECCCCCCCCCCEEECCCHHHCCCCEEEEEEHHHHHHHH
QDSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPIRINFTCEQADVGVPEAYERL
CCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
IHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESG
HHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCC
FKWWLDQETKK
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9298659 [H]