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The map label for this gene is gntK [H]

Identifier: 222096843

GI number: 222096843

Start: 3133229

End: 3134770

Strand: Reverse

Name: gntK [H]

Synonym: BCQ_3183

Alternate gene names: 222096843

Gene position: 3134770-3133229 (Counterclockwise)

Preceding gene: 222096844

Following gene: 222096842

Centisome position: 60.12

GC content: 37.94

Gene sequence:

>1542_bases
ATGGTGAGTTCAAAATATATGATTGGTGTAGACATTGGGACAACTAGTACAAAATCAGTTCTATTTTCTACGGATGGATC
TGTTATTGCAAGTCATGGAATTGAATATCCTTTATATTCTCCTACGCCGGAAACAGCAGAACAAGACCCAGAAGAAATTT
TTCGTGCAGTAATACATACGATTAAAGAAACTGTACAGTCAAGTAGTGTACAGCCGCATGATATTCTTTGTGTTTCTTTT
AGTTCGGCAATGCATAGTATCATTGCTGTAGATGAGAAGGGAAAGCCGTTAACGAGATGTATTACTTGGGCAGATAATAG
AAGTGCAAGCTGGGCAGAGAAAATAAAGAATGATATGAATGGTCATGAAATTTATTTGCGGACTGGGACACCAATTCATC
CGATGTCACCACTTTCGAAATTAGTTTGGTTACAGAATGAACAGGCAGAATTGTTCGCAAAAAGTTATAAATTTATTTCT
ATTAAAGAGTATGTTTTTTATAAGTTATATAAGGAGTATGTAATTGATTATTCTATAGCATCAGCAACAGGGATGTTTAA
TTTGGAATCTTTAAAATGGGATGAAGAGGCTTTACATATTGCGGGAATTACAGATGACAAGCTTTCTAAACTCGTTCCAA
CAACGCACAGTTTAACAGGATTAGATGAAGAGCTTGCCAAAGAGATGAATGTACTTGTTTCTACGCCTTTTGTAGTAGGA
GCGAGTGATGGAGTCCTATCCAATTTAGGTGTAAATGCAATAGATCCTGGCGTTGTTGCTGTGACAATTGGTACAAGCGG
TGCGATACGTGCTGTAACAAATCGTCCTGTAACAGATCCAAAAGGTAGAATTTTTTGTTACGCCTTAACTGAAGAACATT
GGGTAATTGGTGGACCAGTTAATAACGGTGGTATGATTTTCAGATGGGCTCGTGATCAATTAGGCACTTCAGAGATTGAG
CTTGCGAAGCGTTTAGGAAAAGATCCATATGAAGTGCTTACTGAAATAGCAGCAAAAGTGAGTCCGGGGTCCGACGGTTT
ATTATTTCACCCGTATTTAGCAGGAGAAAGAGCTCCTTTATGGAATGCAAATGCGCGAGGATCTTTCTTTGGACTTGGAT
TGCATCATAAGAAAGAACATCTTATCCGTGCTGTTTTAGAAGGAGTAATTTATAATTTATACACCGTTCTTCTCGCTTTA
AAAGAACTCATTGGTGAACCGAAAAAAATTCAAGCGACAGGTGGTTTTGCAAGATCGGAACTTTGGAGACAGATGATGGC
AGATATTTTCCATCAAGACGTATATGTTCCGGAAAGTTTTGAAAGCTCTTGCTTAGGAGCAGCAATCCTCGGTTTATATA
GTTTAGGTGAAGTAGATACGTTGCATGTAGTTTCTGAAATGGTAGGGGCGAATTTCCACCATGAACCAAACATGGAAAGT
GTAGAAAAGTATAAAGATTTAACACCAATCTATATTCGTCTGTCTCGTCAATTGGAAGAAGAATATGAAAGTATAGCAGC
GTACCAAAAAAAGTGGGTTTAA

Upstream 100 bases:

>100_bases
TTTATCGCTTTTGGAGGAGTTTTACTACTCGATATGTTTGTTTAAAATAAGGATGTTTTTATAGTGGGATACTGTAGTAA
TTTTTTGTTAGGAGGAAGAA

Downstream 100 bases:

>100_bases
AAGCTATTTAACAAGAAAATATGGTAACGTATAAAGAGGTACTCTAATTTTTTAGGATACTCTTTCAACATAAAACATTA
TAGGAAGTAAGATGAATGAA

Product: gluconate kinase (2-dehydro-3-deoxygluconokinase)

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLESLKWDEEALHIAGITDDKLSKLVPTTHSLTGLDEELAKEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEEHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVSPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Sequences:

>Translated_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLESLKWDEEALHIAGITDDKLSKLVPTTHSLTGLDEELAKEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEEHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVSPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
>Mature_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLESLKWDEEALHIAGITDDKLSKLVPTTHSLTGLDEELAKEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEEHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVSPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=483, Percent_Identity=25.879917184265, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI41393575, Length=453, Percent_Identity=26.4900662251656, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI189409120, Length=462, Percent_Identity=26.6233766233766, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI4504007, Length=462, Percent_Identity=26.6233766233766, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI42794763, Length=463, Percent_Identity=25.7019438444924, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI164663828, Length=547, Percent_Identity=22.8519195612431, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=27.5303643724696, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787789, Length=502, Percent_Identity=28.6852589641434, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI1790361, Length=501, Percent_Identity=25.9481037924152, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=22.8744939271255, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1789168, Length=379, Percent_Identity=23.7467018469657, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=459, Percent_Identity=25.0544662309368, Blast_Score=122, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321755, Length=536, Percent_Identity=25.3731343283582, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24655555, Length=470, Percent_Identity=25.1063829787234, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655560, Length=470, Percent_Identity=25.1063829787234, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655570, Length=470, Percent_Identity=25.1063829787234, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655574, Length=470, Percent_Identity=25.1063829787234, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24655565, Length=470, Percent_Identity=25.1063829787234, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17864214, Length=479, Percent_Identity=24.2171189979123, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24656367, Length=549, Percent_Identity=22.5865209471767, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357867, Length=562, Percent_Identity=22.0640569395018, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24654573, Length=423, Percent_Identity=23.6406619385343, Blast_Score=101, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24657106, Length=562, Percent_Identity=23.3096085409253, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24657102, Length=562, Percent_Identity=23.3096085409253, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24656372, Length=361, Percent_Identity=21.606648199446, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56910; Mature: 56910

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQSSSVQPHDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCEEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKSYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
SATGMFNLESLKWDEEALHIAGITDDKLSKLVPTTHSLTGLDEELAKEMNVLVSTPFVVG
HHCCCEECCCCCCCCCCEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHHHHHEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEEHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCC
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVSPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQSSSVQPHDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCEEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKSYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
SATGMFNLESLKWDEEALHIAGITDDKLSKLVPTTHSLTGLDEELAKEMNVLVSTPFVVG
HHCCCEECCCCCCCCCCEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHHHHHEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEEHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECCC
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVSPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]