Click here to switch to the map view.

The map label for this gene is serC [H]

Identifier: 222096735

GI number: 222096735

Start: 3032649

End: 3034034

Strand: Reverse

Name: serC [H]

Synonym: BCQ_3075

Alternate gene names: 222096735

Gene position: 3034034-3032649 (Counterclockwise)

Preceding gene: 222096736

Following gene: 222096734

Centisome position: 58.19

GC content: 35.93

Gene sequence:

>1386_bases
TTGGTTCTATGCCGGCGCTTGTGGACACTATTTATTGGCTCATTGGTCTTTCTGCAATTTATCAAATTTTTGATCGGTTC
TTTACGGATAATTAGCTATTATTCTTTTATTACTAGAGTGTTAAGTACGATTATGTACTTAACACTTTTTTATATGTTTA
TAAAAAAGTTTACACATGCAAGCGATTCCATTGCTTCTTGCGCCGTAATACTAGAAAAGAAATTGACCGTGTCTTGTATT
GTGGGTTATAATTCAGAAAGTTTAAAAAATATTAAAATGAGAAATAGGGAGGTCATCCGGGTGATGGAAAGAGTGTATAA
TTTTTCAGCAGGACCATCAATACTCCCTTTGCCAGTTTTAGAGAAAGTGCAAAAGGAGCTTGTAAATTATAACGGGACAG
GCATGTCTATTATGGAAATGAGTCATAGATCTTCTTATTTTCAAAGTATTATAGATGAAGCGGGTAGCTTACTTCGTGAA
TTAATGAACATTCCTGATGAGTATGAAGTATTGTTTTTACAAGGTGGTGCTTCATTACAATTCTCTATGATACCGTTAAA
TTTAATGAATACGTATAAAAAAGCAGGGTACGTATTGACTGGTTCATGGTCTAAAAAGGCACTGCAAGAAGCTGAAAAAG
TTGGAGAAGTACAAGTGATTGCTTCTTCTGAAAATGAGAAGTTTACGACAATTCCTAAACTGGATGGTTTACTAGGCGAT
GAAAAACTAGATTATGTACATATAACAACGAACAATACAATTGAGGGTACGAAATATGTGGACATTCCACATGTAGATAA
AGTACCACTCGTTGCGGATATGTCCTCAAATATTTTATCAGAACGATATGATGTTTCAAAGTTTGGTCTTATATATGCGG
GAGCGCAAAAGAATCTAGGGCCAGCGGGCTTAACGATTGCAATTATAAAAAGAGATTTAATTGGGGGAGCAGATCGCTCT
TGTCCTACAATGTTAAACTATGAAACTTACAGCAAAAATAACTCCTTATATAATACACCGCCGTCCTTTAGTATTTACGT
AACGAAACTTGTACTAGAGTGGCTGAAAGAGCAAGGTGGGGTATCTGCGATTGAAGAACAAAATAGAATGAAATCTTCAC
TACTTTATAATTTCTTAGATGAATCAAAATTGTTTACTTCACCAGTTGATCGTACGTATCGATCACTTATGAACATTCCG
TTTACAACACCGTCAGAAGAGCTGAACAGTGAGTTTCTACAAAAAGCGAAAGAACGAGGACTTGTTACACTAAAAGGACA
TCGATCAGTCGGTGGTATGCGCGCTAGTATTTACAATGCGATGCCAGCACACGGCGTACAGCAATTAGTAAATTATATGA
AGGAATTTGAGCTTGAGAATAGATAG

Upstream 100 bases:

>100_bases
ATAATGAAATTTTTGTCTTACCTTACAGTAATTTTGGTGATTCTTGGCGGTTTGAATTGGTTATTTGTAGCGTTAGATTA
CAATGTAGTTGAGAAATGGT

Downstream 100 bases:

>100_bases
GGAGATGGGGATATGTTTCGTGTTCAAACGTTAAATCAAATTGCAGAAAAAGGTTTGCAAGTGCTTAGCGGAGAGCACTA
TGAAGTAGGGGAGAGAATGG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MVLCRRLWTLFIGSLVFLQFIKFLIGSLRIISYYSFITRVLSTIMYLTLFYMFIKKFTHASDSIASCAVILEKKLTVSCI
VGYNSESLKNIKMRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRE
LMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGD
EKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRS
CPTMLNYETYSKNNSLYNTPPSFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDRTYRSLMNIP
FTTPSEELNSEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR

Sequences:

>Translated_461_residues
MVLCRRLWTLFIGSLVFLQFIKFLIGSLRIISYYSFITRVLSTIMYLTLFYMFIKKFTHASDSIASCAVILEKKLTVSCI
VGYNSESLKNIKMRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRE
LMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGD
EKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRS
CPTMLNYETYSKNNSLYNTPPSFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDRTYRSLMNIP
FTTPSEELNSEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
>Mature_461_residues
MVLCRRLWTLFIGSLVFLQFIKFLIGSLRIISYYSFITRVLSTIMYLTLFYMFIKKFTHASDSIASCAVILEKKLTVSCI
VGYNSESLKNIKMRNREVIRVMERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRE
LMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGD
EKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRS
CPTMLNYETYSKNNSLYNTPPSFSIYVTKLVLEWLKEQGGVSAIEEQNRMKSSLLYNFLDESKLFTSPVDRTYRSLMNIP
FTTPSEELNSEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=360, Percent_Identity=47.5, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI10863955, Length=355, Percent_Identity=42.8169014084507, Blast_Score=287, Evalue=1e-77,
Organism=Escherichia coli, GI1787136, Length=366, Percent_Identity=42.896174863388, Blast_Score=317, Evalue=8e-88,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=44.7222222222222, Blast_Score=328, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=391, Percent_Identity=40.920716112532, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=49.0358126721763, Blast_Score=343, Evalue=2e-94,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 52150; Mature: 52150

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLCRRLWTLFIGSLVFLQFIKFLIGSLRIISYYSFITRVLSTIMYLTLFYMFIKKFTHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDSIASCAVILEKKLTVSCIVGYNSESLKNIKMRNREVIRVMERVYNFSAGPSILPLPVL
CHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQ
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
FSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGD
EEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHCCCCC
EKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLG
CCCCEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCHHHCCEEEECCCCCCC
PAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPPSFSIYVTKLVLEWLKEQGG
CCCCEEEEEHHHHCCCCCCCCCCEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
VSAIEEQNRMKSSLLYNFLDESKLFTSPVDRTYRSLMNIPFTTPSEELNSEFLQKAKERG
CHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
LVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
EEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVLCRRLWTLFIGSLVFLQFIKFLIGSLRIISYYSFITRVLSTIMYLTLFYMFIKKFTHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SDSIASCAVILEKKLTVSCIVGYNSESLKNIKMRNREVIRVMERVYNFSAGPSILPLPVL
CHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
EKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQ
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEE
FSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGD
EEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHCCCCC
EKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLG
CCCCEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCHHHCCEEEECCCCCCC
PAGLTIAIIKRDLIGGADRSCPTMLNYETYSKNNSLYNTPPSFSIYVTKLVLEWLKEQGG
CCCCEEEEEHHHHCCCCCCCCCCEECCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
VSAIEEQNRMKSSLLYNFLDESKLFTSPVDRTYRSLMNIPFTTPSEELNSEFLQKAKERG
CHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
LVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
EEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA