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The map label for this gene is ndhF [H]

Identifier: 222096640

GI number: 222096640

Start: 2920822

End: 2922354

Strand: Reverse

Name: ndhF [H]

Synonym: BCQ_2980

Alternate gene names: 222096640

Gene position: 2922354-2920822 (Counterclockwise)

Preceding gene: 222096641

Following gene: 222096639

Centisome position: 56.05

GC content: 36.59

Gene sequence:

>1533_bases
ATGTTAATTTCGCTAAGTTCATCAACACTGTTAACATTATTTTTTATCGCGCTTAGTGCTTCTTGGCTAAGTGGATTATT
GTTTTTACATGCAAGGATGCCTTTACGTTTTGTTCATATCCATATTGGTATCGCTGCTTTGCCTTCATTGGTTTCTTTAC
TTGCACTTGTTAATCACAATGGAGATAGAGTTGTGGGGCCTTGGCATCTAGATACTTTAGCTTGGTTCATGGCTTTCTTC
GTTCTTACAATTGGTTTAATCATTCAGCGATTTTCTGTACGTTACTTAATGGGAGACCGCTCATATCGAAAATACTTTGC
ACTTTTTACATTTACTACAGGTGTATCTTCGGTTGCATGGTTAAGCGATGATCTTCGCTTCATGATTATGTGTTGGGGAG
CAACTCTTATAGGATTGGTTCTACTCATCGGGCTAAATAAAGGGTGGAAGGTAGTTAGTGAAGCAACAAAAATCTCAGGC
TATTTATTTACAATAAGTTGGATTGCCTTGCTATCAGCTATCATTTGGTTGTTTCAAATAACTGGACAGTGGCAGTTAAC
ATCAGTTTTAACGAATGAAAATGTAGCTCAATTTGGAACATTGGAGAAAACAGGAATTAACTTATTGATTATAGTAGCTG
TGATGATTCCAGCAGCACAATGGCCTTTCCAAAGATGGTTAATTGAATCAGCTGTTGCTCCAACTCCTGTTTCTGCTATT
ATGCATGCGGGTTTAGTAAATGCTGGCGGTATCATGTTAACTAGATTTTCGCCACTTTTTCATGATGATATTGCACAAAT
CATTTTACTCATTTTCTCTAGTATTTCTGTCTTAATAGGTACAGGAATTAGTTTAGTCCAAGTTGATTATAAACGTCAGC
TAGTAGGTTCGACGATTGCACAAATGGGATTTATGCTGATTCAATGCGCATTAGGGGCCTATTTAGCAGCTGTTATTCAT
TTAATTTTACACGGTTTATTTAAAGCCACACTGTTTTTACAAGCTGGTTCTTCCGTACAACGTTTTGATGGAGTGAAGCA
ATCTAATGAAAAGATGTCCAATTTATGGATTATGTTCGGACGTGTTTTAGGATTATTTATAGCAATTGCTTTCTGGTTTA
TGACTTCTGGAGAGGGGTATGAATTAGTTAGTGCGTTAATCTTAGGATGGTCATTATACTTTTCGTGGAAACAGCTTGTT
GTTTTTGGAGAGGGAAGAATGGGAAGAATTGCTGGCTTAATAGTTTTGAGTGGATTTTCTCTCATTTACTTTACTGTTCA
TAACTCTCTTTATAAATGGTTGCATACTGACATGTATCAAAGTGTTCAACCCTCAGCTCCAGCCGTTATTTTTGTTATAT
GTATCTTACTATTTAGTAGTGTTATTTGTACTTTCGTTACTCGTAATCAATCTTCTACTTTATTCGCTGTACTTTATCTT
TGGTTAGTTCGAGTAGGTGAGGCGAGACGAAAGTCAGTAGAAAGTCACCCAAGCTATCTGAAACATTATGTATCAAAGGG
AGGTAATTCGTGA

Upstream 100 bases:

>100_bases
CGATGTACGAAAAAGAGTGAATGAAAATTAAAATTAAAAAAACTATCGTAATGAAAAGGAATTTTTATAAGTTATTTTCG
TTTGGAAGGGAGTATTTTAC

Downstream 100 bases:

>100_bases
TGAGCATACAGTCAATCGTAACGAAAGAAACTTTAAAAAAGAAAGATACAAACATTGAAATACAAGAAAAGAATATGAAT
GATTTAGTTGAATCTGCTAG

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIMCWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRFDGVKQSNEKMSNLWIMFGRVLGLFIAIAFWFMTSGEGYELVSALILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQSVQPSAPAVIFVICILLFSSVICTFVTRNQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS

Sequences:

>Translated_510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIMCWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRFDGVKQSNEKMSNLWIMFGRVLGLFIAIAFWFMTSGEGYELVSALILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQSVQPSAPAVIFVICILLFSSVICTFVTRNQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
>Mature_510_residues
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHNGDRVVGPWHLDTLAWFMAFF
VLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAWLSDDLRFMIMCWGATLIGLVLLIGLNKGWKVVSEATKISG
YLFTISWIALLSAIIWLFQITGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAVIH
LILHGLFKATLFLQAGSSVQRFDGVKQSNEKMSNLWIMFGRVLGLFIAIAFWFMTSGEGYELVSALILGWSLYFSWKQLV
VFGEGRMGRIAGLIVLSGFSLIYFTVHNSLYKWLHTDMYQSVQPSAPAVIFVICILLFSSVICTFVTRNQSSTLFAVLYL
WLVRVGEARRKSVESHPSYLKHYVSKGGNS

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=140, Percent_Identity=32.8571428571429, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788614, Length=402, Percent_Identity=27.1144278606965, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788831, Length=146, Percent_Identity=32.1917808219178, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788613, Length=270, Percent_Identity=28.1481481481481, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56739; Mature: 56739

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDRVVGPWHLDTLAWFMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAW
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
LSDDLRFMIMCWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLSAIIWLFQI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEHHHCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIA
HHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRFDGVKQSNEKMSNLWIMFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
RVLGLFIAIAFWFMTSGEGYELVSALILGWSLYFSWKQLVVFGEGRMGRIAGLIVLSGFS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDMYQSVQPSAPAVIFVICILLFSSVICTFVTRNQSSTLFAVLYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MLISLSSSTLLTLFFIALSASWLSGLLFLHARMPLRFVHIHIGIAALPSLVSLLALVNHN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCC
GDRVVGPWHLDTLAWFMAFFVLTIGLIIQRFSVRYLMGDRSYRKYFALFTFTTGVSSVAW
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHH
LSDDLRFMIMCWGATLIGLVLLIGLNKGWKVVSEATKISGYLFTISWIALLSAIIWLFQI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGQWQLTSVLTNENVAQFGTLEKTGINLLIIVAVMIPAAQWPFQRWLIESAVAPTPVSAI
CCCEEEEHHHCCCCHHHHCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIA
HHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAVIHLILHGLFKATLFLQAGSSVQRFDGVKQSNEKMSNLWIMFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHH
RVLGLFIAIAFWFMTSGEGYELVSALILGWSLYFSWKQLVVFGEGRMGRIAGLIVLSGFS
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
LIYFTVHNSLYKWLHTDMYQSVQPSAPAVIFVICILLFSSVICTFVTRNQSSTLFAVLYL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
WLVRVGEARRKSVESHPSYLKHYVSKGGNS
HHHHHCHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]