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The map label for this gene is glnK [H]

Identifier: 222096615

GI number: 222096615

Start: 2887682

End: 2888998

Strand: Reverse

Name: glnK [H]

Synonym: BCQ_2955

Alternate gene names: 222096615

Gene position: 2888998-2887682 (Counterclockwise)

Preceding gene: 222096616

Following gene: 222096614

Centisome position: 55.41

GC content: 31.74

Gene sequence:

>1317_bases
GTGATTATTTTGAATCTTAGTAATTTAGTAAAAAAAGACATCTATATTCTCGTTTTAATGATACTTACAGTACCCTTAGT
AGGTGAAATAAAGTCATTTCCTTTAAATGAAACATTTAGAATGAGCTTTGGTGCACCAACATTTTTCTTTTTTTTGTTAT
TGTTTCGACGAATTCCAGCATTTTTACCGGGTTTTTTAACAGCGATAGTCGTGGTAGTATTTCGTATCTCAATGGATGTC
ATTATAAAGGGAAATATGGATTGGCTAGCCGCTTTTCATACTCACTATCCTAGTTTTTTCTTTTATTTTACTTATTCGTA
TCTCTTTCATTTAGCAAAAATTAAACGTTTTTATCATCAACCACTAATGATTGGTTTGATTGGTTGCATGATTGAAATAC
TGTCAGACTGTGTGGAATTAATGATTCAATATTTCGTATTAAAAACATCGATCACATCCGAGGCAATAAATGAGATCATT
GTTATCGCATGTTCCCATAGTTTTATAGTTCTAAGCTTTTTCAATATGATGAAATTGTATGAAGCGCAATCAAGGGAGAA
ACACATAAAGAAACAAAATGAACACATGCTCATGCTCATCTCTAATTTATATGAAGATGCTGTTCATTTAAAAAAAACAT
TACAAGATGCTGAGAATATAACAAAAAAATCCTATGATTTATATAAAACTTTAGACTCTTTTGAGCACAAACAGATGGAT
TTTCAGTTTGGGGATTTAAGGCAACAGGCATTACAAATTGCTGGTGAGGTTCATGACGTTAAAAAGGATAACCAACGTAT
TTTTGCAGGACTTTCAAAATTAATTTCTGATGAAAGTTTTACAGATTATATGTCTGTACATGAACTAGTAAATATCATTA
TACGGGCAAATGCGAAATATGCACGGTTGCTAGAGAAAGACATCCAATTTGTGTATAAAATTGATGGTGTGCATCCTCAT
TATCATATTTACACAATCTTATCTATTATAAATAATATCGTTACAAACGCTGTAGAGGCTATCCAAGGTATGGGAACCAT
CACAATTGACATTAATAAAGACCACCATTTTGTTGAATTTCAAATAGGCGATAATGGTCCCGGTATTTCTTCAAAATATA
AAGATTCAATTTTTGAGCCTGGTTTTACTTCTAAATATGATGATTTAGGCAATCCATCGACAGGTATCGGATTATCGTAT
GTTAAAGAAATGGTCGAACAACTTGAAGGTGATGTTACGATTGAGGACAGAACCGAAGGAAAAGGATCAATTTTTATAAT
TAGATTAGGGATTGATCATATAATTTCGAAAGGGTGA

Upstream 100 bases:

>100_bases
CTTTCGTTTATATCTTATTTATCAGTTTTTGAAAAAAATAGAGTAAGTATTGTATTAATGCAAATAGGTTTGTATACTGA
CTGTTAGGCGAAAGTGAGAA

Downstream 100 bases:

>100_bases
TTCTATGTATTTTTATATAGTAGATGATGAAAAAGCGGTTCGCTCAATGTTGGCTCAAATTATCGAGGATGAAGATCTTG
GGGAGGTTATAGGAGAAGCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSREKHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFEHKQMD
FQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVHPH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSY
VKEMVEQLEGDVTIEDRTEGKGSIFIIRLGIDHIISKG

Sequences:

>Translated_438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSREKHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFEHKQMD
FQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVHPH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSY
VKEMVEQLEGDVTIEDRTEGKGSIFIIRLGIDHIISKG
>Mature_438_residues
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPAFLPGFLTAIVVVVFRISMDV
IIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQPLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEII
VIACSHSFIVLSFFNMMKLYEAQSREKHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFEHKQMD
FQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKYARLLEKDIQFVYKIDGVHPH
YHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEFQIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSY
VKEMVEQLEGDVTIEDRTEGKGSIFIIRLGIDHIISKG

Specific function: Member of the two-component regulatory system glnK/glnL that positively regulates the expression of the glsA-glnT operon in response to glutamine. Probably activates glnL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=129, Percent_Identity=29.4573643410853, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50349; Mature: 50349

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHHHHHHH
FLPGFLTAIVVVVFRISMDVIIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQ
HHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
PLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEIIVIACSHSFIVLSFFNMMKLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
EAQSREKHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFEHKQMD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
ARLLEKDIQFVYKIDGVHPHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEF
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
QIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSYVKEMVEQLEGDVTIEDRTEG
EECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCC
KGSIFIIRLGIDHIISKG
CCCEEEEEECHHHHHCCC
>Mature Secondary Structure
MIILNLSNLVKKDIYILVLMILTVPLVGEIKSFPLNETFRMSFGAPTFFFFLLLFRRIPA
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEECCCCHHHHHHHHHHHHHHH
FLPGFLTAIVVVVFRISMDVIIKGNMDWLAAFHTHYPSFFFYFTYSYLFHLAKIKRFYHQ
HHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
PLMIGLIGCMIEILSDCVELMIQYFVLKTSITSEAINEIIVIACSHSFIVLSFFNMMKLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHH
EAQSREKHIKKQNEHMLMLISNLYEDAVHLKKTLQDAENITKKSYDLYKTLDSFEHKQMD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
FQFGDLRQQALQIAGEVHDVKKDNQRIFAGLSKLISDESFTDYMSVHELVNIIIRANAKY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
ARLLEKDIQFVYKIDGVHPHYHIYTILSIINNIVTNAVEAIQGMGTITIDINKDHHFVEF
HHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEE
QIGDNGPGISSKYKDSIFEPGFTSKYDDLGNPSTGIGLSYVKEMVEQLEGDVTIEDRTEG
EECCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCC
KGSIFIIRLGIDHIISKG
CCCEEEEEECHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8011666 [H]