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The map label for this gene is kipR [H]

Identifier: 222096567

GI number: 222096567

Start: 2841185

End: 2841937

Strand: Reverse

Name: kipR [H]

Synonym: BCQ_2907

Alternate gene names: 222096567

Gene position: 2841937-2841185 (Counterclockwise)

Preceding gene: 222096568

Following gene: 222096566

Centisome position: 54.5

GC content: 37.85

Gene sequence:

>753_bases
ATGAGTATAAATAAAACGGCAGTTAAGACAATGGATATTTTACAGTTGTTTTATGAGCATGAAGAGCTAAGTTTAACAGA
AATGGTTCAGCTTACAAGTATGCCGAAAACATCGGTTTATCGTTTAATTGGCTCGTTAGAAGAAATGGAGTTTTTACAAA
AAAACGAAAAGGGGAAATATCGTCTAGGAGTCGTTTTTTTACGGTTCGGTCAACTTGTTTCACAAAGACTATCCGTAAGA
AATATTGCAATTCCATATATGAAAGAGCTTAGAGATAGTTTAGGGCAGGCAGTTAATTTAATTATTCAAGATGGTAATGA
CGCGATTTATGTGGAAAAGATGGAAGGCGTTCAGCCTGTACGTGTGTATACGGCGGTTGGAAGACGAGCGCCACTTTATG
CCGGTGCATGTCCGAGAATTTTACTATCGTATTTCTCAGAGGAAGAGAAACAGAAATACATAGAGGAAACGGATTTAAAA
CAATTTGCAGATGGAACAATCGTAGATAAGAAACAATTGTTAGAAGTGTTACAAATGGCGAAAAAGGAAGGACATACCAT
TAGTTATTCGGAGTTAGAAAATCATACAGCAGCTATAGCAGTGCCCATTTTCGCAAGCGACGGAACGGTTGTAGCAGGCA
TTAGTATTTCAGGATTAGCAATTGAGTACAACGAAAGTAACATTCCATATTTTATCGCGAAGGTAAAAGAGACAGCGAAT
CGCATTTCGAAAGAACTCGGCTTTTTGGCATAG

Upstream 100 bases:

>100_bases
TTGTTGATAGAATTGAAAGAATATTTTATAATTTTAAATTATATGTTTGTTTCGAAAAATGGAATTTAAGTTCCGAAATT
CGGAATAAGAGGGAGATGGA

Downstream 100 bases:

>100_bases
AAAGAGGGAGTAGGATGAAATTTTCTGCGTTAGGGGATCAAGCAATTATTGTTACATTTGGTGAAGGAATTGGAATGGAT
ACTTATGAAAAAGTGCAGCA

Product: transcriptional regulator, iclr family

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSINKTAVKTMDILQLFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSQRLSVR
NIAIPYMKELRDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKQKYIEETDLK
QFADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAVPIFASDGTVVAGISISGLAIEYNESNIPYFIAKVKETAN
RISKELGFLA

Sequences:

>Translated_250_residues
MSINKTAVKTMDILQLFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSQRLSVR
NIAIPYMKELRDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKQKYIEETDLK
QFADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAVPIFASDGTVVAGISISGLAIEYNESNIPYFIAKVKETAN
RISKELGFLA
>Mature_249_residues
SINKTAVKTMDILQLFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKYRLGVVFLRFGQLVSQRLSVRN
IAIPYMKELRDSLGQAVNLIIQDGNDAIYVEKMEGVQPVRVYTAVGRRAPLYAGACPRILLSYFSEEEKQKYIEETDLKQ
FADGTIVDKKQLLEVLQMAKKEGHTISYSELENHTAAIAVPIFASDGTVVAGISISGLAIEYNESNIPYFIAKVKETANR
ISKELGFLA

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=252, Percent_Identity=27.7777777777778, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1788131, Length=244, Percent_Identity=28.6885245901639, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786715, Length=221, Percent_Identity=32.1266968325792, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788581, Length=241, Percent_Identity=24.896265560166, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789999, Length=230, Percent_Identity=26.5217391304348, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=26.9911504424779, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=24.5614035087719, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28143; Mature: 28012

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINKTAVKTMDILQLFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKY
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCE
RLGVVFLRFGQLVSQRLSVRNIAIPYMKELRDSLGQAVNLIIQDGNDAIYVEKMEGVQPV
EHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCHH
RVYTAVGRRAPLYAGACPRILLSYFSEEEKQKYIEETDLKQFADGTIVDKKQLLEVLQMA
HHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KKEGHTISYSELENHTAAIAVPIFASDGTVVAGISISGLAIEYNESNIPYFIAKVKETAN
HHCCCEEEHHHHCCCCEEEEEEEEECCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHH
RISKELGFLA
HHHHHHCCCC
>Mature Secondary Structure 
SINKTAVKTMDILQLFYEHEELSLTEMVQLTSMPKTSVYRLIGSLEEMEFLQKNEKGKY
CCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCE
RLGVVFLRFGQLVSQRLSVRNIAIPYMKELRDSLGQAVNLIIQDGNDAIYVEKMEGVQPV
EHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCHH
RVYTAVGRRAPLYAGACPRILLSYFSEEEKQKYIEETDLKQFADGTIVDKKQLLEVLQMA
HHHHHHCCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
KKEGHTISYSELENHTAAIAVPIFASDGTVVAGISISGLAIEYNESNIPYFIAKVKETAN
HHCCCEEEHHHHCCCCEEEEEEEEECCCCEEEEEEEEEEEEEECCCCCCCHHHHHHHHHH
RISKELGFLA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]