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The map label for this gene is yrbD [H]

Identifier: 222096329

GI number: 222096329

Start: 2610665

End: 2612155

Strand: Reverse

Name: yrbD [H]

Synonym: BCQ_2669

Alternate gene names: 222096329

Gene position: 2612155-2610665 (Counterclockwise)

Preceding gene: 222096330

Following gene: 222096328

Centisome position: 50.1

GC content: 37.16

Gene sequence:

>1491_bases
ATGGAGCAATTAGTAGAGTGGTTAGTAGGGCAAGTGTGGAGTATTGGTTTAGTTGTTTTCGCGTTAGGAGCAGGTGTGTA
TTTTACAATTGCAACTCGTTTTCTTCAAATTCGTTATTTTAAAGAGATGATTAAACTATTATTTGAAGGGAAGAGCTCAG
AAACGGGAATATCATCCTTTCAAGCATTTTGTTTAGCTTTATCAGGTAGGGTTGGAATAGGTAATATTGCAGGGGTCGCG
ACAGCTATCGCTTTTGGCGGGCCGGGAGCTGTATTTTGGATGTGGGTAATGGCTCTATTAGGAGCAGCTAGTGCATTTGT
TGAATCAACATTATCTCAAGTATATAAAAGTAAAGTTGGAAATGAATATCGCGGTGGTACACCGTATTTCATTGAAAAAG
GCTTAAACATGAAATGGTTTGCAATCATTGTAGCAGTCGTTGTAACACTTTCATATGGTGTTTTATTACCAGGTATTCAA
TCTAGTAGTATCGCAGTTGGATTCGAAAACTCTAATGGGATTAGCAAGTATATAACTGGTATATTGTTAGTTGTATTATT
AGCAGCAATCATTTTTGGTGGCGTAAAGAGAATTGCCGGCGTTTCTCAAATGCTCGTTCCATTTATGGCAATTGGATATG
TAATTGTTACATGTATCGTATTAATTGCGAATGTAACGGAAATTCCAAGTATGTTTGCTTTAATTTTCTCAAGTGCTTTC
GGTGTAAATGAAATGTTTGGCGGAATCGTTGGTGCAGCAATTGCATGGGGCGTGAAGCGGGCTGTATTTTCAAATGTTGC
TGGCGTTGGAGAAGCGACGTATAGTTCCGCTGCGGCTGAAGTATCTCACCCAGCAAAACAAGGGTTAGTTCAAGCGTTTT
CCGTATACATTGATACAATTGTCGTATGTACAGCGACAGCTCTTATGATTTTAATAACAGGTATGTACAATGTTATACCT
GAAGGGAAAAGCGCTATTGTAAAGAATATGGGGAATGTAGATGCTGGTCCAATCTATACACAACAAGCTGTTGAAACTGT
TATGACTGGGTTTGGTCCATTATTCATTTCAATCGCAATTTTCTTCTTCGCATTTACAACTTTACTCGCTTACTACTATA
TCGCTGAAACGACACTTACTTATTTAGATCGTGAGGTTAAATATAGCTGGTTAAAATCAGTATTAAAAATTGGGTTTTTA
ATTATGGTTTATATCGGTAGCGTAGAATCAGCGTCGCTTTTATGGAATCTTGGAGATTTAGGAATTGGTAGTATGGCATG
GTTAAACTTAATCGCGATTCTATTATTAAGTAAAATCGCATTAAAAGTGTTAAAAGATTATGAAGCGCAGAAAAAAGTAG
GGAAAGATCCAGTATTTGATCCTAAAAATGTAGGGATTGAAGGTTTAACATTTTGGGAAGAGAGAAGTAAAGAGGTTCAA
AGAAAAAACTCTAAAGAACAAGCGGTAGTGGATGATAGTCTGAAACTGTAG

Upstream 100 bases:

>100_bases
ATGAAATAATGAGATAGACGGACAACTGGAAGTTTTCATAATAGTTGTCCGTTTTCTTATATATAAAATAGTTTTCTAAA
GAATGATAAGGGGGATTTGG

Downstream 100 bases:

>100_bases
TTTAAATAAACTGAATATTCGTTCTATTAAATGAGGTATATTGCCTTCTTTTCATCACATACTACAGTAGGTACAGATAA
TTTGAATGGGGGTAATAATA

Product: sodium/proton-dependent alanine carrier protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLNMKWFAIIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNMGNVDAGPIYTQQAVETVMTGFGPLFISIAIFFFAFTTLLAYYYIAETTLTYLDREVKYSWLKSVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYEAQKKVGKDPVFDPKNVGIEGLTFWEERSKEVQ
RKNSKEQAVVDDSLKL

Sequences:

>Translated_496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLNMKWFAIIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNMGNVDAGPIYTQQAVETVMTGFGPLFISIAIFFFAFTTLLAYYYIAETTLTYLDREVKYSWLKSVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYEAQKKVGKDPVFDPKNVGIEGLTFWEERSKEVQ
RKNSKEQAVVDDSLKL
>Mature_496_residues
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLNMKWFAIIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNMGNVDAGPIYTQQAVETVMTGFGPLFISIAIFFFAFTTLLAYYYIAETTLTYLDREVKYSWLKSVLKIGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYEAQKKVGKDPVFDPKNVGIEGLTFWEERSKEVQ
RKNSKEQAVVDDSLKL

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=482, Percent_Identity=36.5145228215768, Blast_Score=281, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 53473; Mature: 53473

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QAFCLALSGRVGIGNIAGVATAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVG
HHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEYRGGTPYFIEKGLNMKWFAIIVAVVVTLSYGVLLPGIQSSSIAVGFENSNGISKYITG
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
ILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVCTATALMILITGMYNVIPEGKSAIVKNMGNVDAGPIYTQQAVETVMTGFGPLFISIAI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFFAFTTLLAYYYIAETTLTYLDREVKYSWLKSVLKIGFLIMVYIGSVESASLLWNLGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GIGSMAWLNLIAILLLSKIALKVLKDYEAQKKVGKDPVFDPKNVGIEGLTFWEERSKEVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RKNSKEQAVVDDSLKL
HCCCCHHHHHCCCCCC
>Mature Secondary Structure
MEQLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QAFCLALSGRVGIGNIAGVATAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVG
HHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEYRGGTPYFIEKGLNMKWFAIIVAVVVTLSYGVLLPGIQSSSIAVGFENSNGISKYITG
CCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
ILLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIVLIANVTEIPSMFALIFSSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTI
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VVCTATALMILITGMYNVIPEGKSAIVKNMGNVDAGPIYTQQAVETVMTGFGPLFISIAI
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFFAFTTLLAYYYIAETTLTYLDREVKYSWLKSVLKIGFLIMVYIGSVESASLLWNLGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GIGSMAWLNLIAILLLSKIALKVLKDYEAQKKVGKDPVFDPKNVGIEGLTFWEERSKEVQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RKNSKEQAVVDDSLKL
HCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]