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The map label for this gene is acoR [H]

Identifier: 222096267

GI number: 222096267

Start: 2559876

End: 2561726

Strand: Reverse

Name: acoR [H]

Synonym: BCQ_2607

Alternate gene names: 222096267

Gene position: 2561726-2559876 (Counterclockwise)

Preceding gene: 222096268

Following gene: 222096266

Centisome position: 49.13

GC content: 35.01

Gene sequence:

>1851_bases
ATGCTAGCTTCACCGTTTTACTTACATACATGGAAAAAGTTTGTTGATGAAGGTGTCCTTGATTCGAACCGTATAAACGA
AAGAATTTCAGAGTCATGGTATCGATGTAAACAAGCAAATGTGAATCCTCATATGAATAAAGGTCAGAAAATTTTGTCTT
CTAATATTTTTCAAGACCAAAAGAAAAAGAGTGAAATCTTCCTAGATATAGCAATACCTCAAATACAAAATATGAGAAAA
ACCATTGATGAACTGCAAATGATGGCATTATTAATCGATCCAGACGGTTACGTTCTATCGTTAAGTGGAAATAAACAAAC
GTTGCAACGAGCGAAACAGATTAATTTCATTGAAGGTGTGAAATGGACGGAAGCAGCTGTTGGTACAAATGCGATAGGAA
CCGCGCTTGAGATTGAAGAGGCTATTATGATAAGTGGTACGGAGCATTATTCTGTCGCATCTCATAGCTGGAGCTGTGCG
GCCGCTCCTATTCATAACGATGATGGGAAATTAATTGGCGTTCTAGATTTCTCCTGTCCAATTGAATTTTCGCATCCATA
TATGCTCGGAATGGTAACTTCGATCGCACATGCGATTGAACGTGAATGTAGTATTCGAGTACATCAAAATGAACTGCATT
TAATCCATCGTTTTTTAGATGTAATTGATAGTGATGAACAAGTTGTAATTTGTAATCATCGTGATGTTATCGTTTCTGCA
AGCAAGAGGGTTCGGGAACGAGTATGTAATTGGTCACGGATGAAACTTGAAGATTTAATGCACTATGGATTGAAAACTAA
ATTAGAAGTTCCAGTATACAGTAATAATAGAATGATTGGGAAATGTATTTATGTAAAGGGAAATAAACAAGTAAAATCAT
TTTCAACGTCCCCATTTATAAATGGCATCACTTTTCCTGGAGTGATTGGGACAAGTAGTGCATTTCAACATACATTAGAA
GAAATTAAGCTTGTATCACCAACTGACGCAAGTGTATATGTTTGTGGTGAAACAGGTGTAGGAAAAGAATATGTAGCGAG
AGCGATTCATGAAAATAGTCCAAGAAAAAATGGTCCATTTATAGCTGTTAACTGCGGTTCATTACCGAAAGAATTAATGG
AAAGTGAATTGTTCGGTTATGCTGAAGGAGCGTTTACAGGTGCACGGCGCCAAGGATATAAAGGGAAATTCGAACAAGCA
GACGGAGGAACAATATTTTTAGATGAAATTGGTGAAGTGCCACCAGAGATGCAAGTCGCATTATTGCGTGTTTTACAAGA
ACGAACAGTAAACCCAATTGGCAGTTCAAAAGAGATACCAGTAAATATTCGTATTATTACTGCGACACATAAAGATTTAT
TGCGATTAGTAGAAGAAGGAAAATTCCGTCAAGATTTATATTATCGTTTACATGTTTATCCACTATATGTCCCATCGTTA
ATAGAAAGAAAAGAGGATATTCCGTACTTCATAAAACATTTTTGCAAACGAAAGAATTGGAATGTTGTATTTCCAAAAAG
TATTTGTAATCAATTTTCTCAGCATACATGGCCCGGAAATATTCGAGAATTATTAAATGTATTAGAACGCATATACATTT
TGTCGCAAGGACGAGAAATATGCGAAAAACAAATCTCTTTTTTATTACAAACAATGATGGGAAATCAACCTCATTTTGAA
TTGCAAGCAGAAAATAAAACAGAGAAAACATTAAATTTCCGTGAAAAAATACAGCGTGATAGCATGATTGAAGCGTTAGA
AAAGACAAATGGAAATGTTTCATTAGCTGCAAAACTTTTAGATGTACCTCGAAGTACATTTTATAAACGAATGCAAAAAT
ATAAGTTATAA

Upstream 100 bases:

>100_bases
TGTGTCGTCTTTCTAGTTTTGTTGAAAACGCTTTTATTCAGTTTTATAATAAAAGTATGTTTTTACAAATCTCCAAAATA
ATGAATAGGGAGATGATACA

Downstream 100 bases:

>100_bases
AGTAGATTTTTGTAATCTACTTTTTCTTTGTGGGCTCATGTTCTGTCGGAATGTGCGCTTACCGGGGAAATAATAGAATA
GTTAGAAATTAATTTCCGGA

Product: sigma-54-dependent transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLQRAKQINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKRVRERVCNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKGNKQVKSFSTSPFINGITFPGVIGTSSAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVNPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMGNQPHFE
LQAENKTEKTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Sequences:

>Translated_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLQRAKQINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKRVRERVCNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKGNKQVKSFSTSPFINGITFPGVIGTSSAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVNPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMGNQPHFE
LQAENKTEKTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL
>Mature_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNKQTLQRAKQINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKRVRERVCNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKGNKQVKSFSTSPFINGITFPGVIGTSSAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVNPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMGNQPHFE
LQAENKTEKTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=41.8960244648318, Blast_Score=266, Evalue=4e-72,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=41.4110429447853, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=42.5396825396825, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=37.6947040498442, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788550, Length=318, Percent_Identity=40.251572327044, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI1789087, Length=317, Percent_Identity=40.3785488958991, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1790299, Length=340, Percent_Identity=36.1764705882353, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=37.5776397515528, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=36.1370716510903, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=24.8840803709428, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1787583, Length=247, Percent_Identity=38.0566801619433, Blast_Score=182, Evalue=6e-47,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.0480349344978, Blast_Score=180, Evalue=3e-46,
Organism=Escherichia coli, GI1789828, Length=322, Percent_Identity=30.4347826086957, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70327; Mature: 70327

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNKQTLQRAKQINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHCCHHCCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEHH
SKRVRERVCNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKGNKQVKSFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEEECCCCEECCCCCCCC
NGITFPGVIGTSSAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVNPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREI
HHHCCCCCHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMGNQPHFELQAENKTEKTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNKQTLQRAKQINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHCCHHCCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEHH
SKRVRERVCNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKGNKQVKSFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEEECCCCEECCCCCCCC
NGITFPGVIGTSSAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVNPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIKHFCKRKNWNVVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREI
HHHCCCCCHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMGNQPHFELQAENKTEKTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]