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The map label for this gene is yjjG [H]

Identifier: 222096235

GI number: 222096235

Start: 2530162

End: 2530839

Strand: Reverse

Name: yjjG [H]

Synonym: BCQ_2575

Alternate gene names: 222096235

Gene position: 2530839-2530162 (Counterclockwise)

Preceding gene: 222096237

Following gene: 222096234

Centisome position: 48.54

GC content: 30.38

Gene sequence:

>678_bases
ATGCTGTTTGATTTAGATGATACGTTACTTAATAGGGATATGGCAGTAGATACATTGTTTTTATTTGTTTTAGAAAAATG
TTATGAAGATGTTAGTGATACAGTTAAAAACAATATGCTACGGAAATTTAAAGAATATGATAAAAGGGAATACGGCATGA
GTGATAAAGCAATAGTTTTAGAATCGTTGTTTGATGAATTCCCGCCGAAGTATAGGTTGCAACGCAATTATATCCAAGAT
TTTTGGAATAAAAATTTCCCTAAATGTTTTTCAATAGACAAAAATACTATTCATTTCTTACATCATATAAAGAAGCACTT
TGAAGTTGGAATTATAACAAATGGCTCAAGTCAGAGGCAAAGGGCTAAAATAATTAACACGAATTTAAACAATTACTTTG
ATACGATCATTATTTCTGAAGAAGTAGGATTGAGTAAACCGGATAAACGTATATTTGAACTAGCATTAAATAAACTTGAT
GTGCAACCAGAAGATGTATTATTTGTTGGAGATGACTTAGAAAAGGATATTGCTGGTCCTCAAAATGCAAATATAAAAGG
TGTGTGGTTTAACCCTCAGAAAATCAAGAATACTACCAAAATACAACCATATGCCGAGATTAACACTTTGGATAGCTTGT
TAAGTTATGTTACGCCACAATATTTTTTTAACAAGTAA

Upstream 100 bases:

>100_bases
CTATTACGAGCTCTTTCATATGAATTGTTTTTTTGATTACTTTTGATGATATCTAGGAAATATAGAAAGGTTGTGAATTT
ATTTGATGGGTTATAAAGCT

Downstream 100 bases:

>100_bases
AATTAATTTCATTGACCGTATTAGCAATAAAAAATAGAGGCAATTTTAATAGCTGCGGTTAATTTAATCTATGATTCATA
CGAAGTTTTGTAAAACAATT

Product: haloacid dehalogenase

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLFDLDDTLLNRDMAVDTLFLFVLEKCYEDVSDTVKNNMLRKFKEYDKREYGMSDKAIVLESLFDEFPPKYRLQRNYIQD
FWNKNFPKCFSIDKNTIHFLHHIKKHFEVGIITNGSSQRQRAKIINTNLNNYFDTIIISEEVGLSKPDKRIFELALNKLD
VQPEDVLFVGDDLEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK

Sequences:

>Translated_225_residues
MLFDLDDTLLNRDMAVDTLFLFVLEKCYEDVSDTVKNNMLRKFKEYDKREYGMSDKAIVLESLFDEFPPKYRLQRNYIQD
FWNKNFPKCFSIDKNTIHFLHHIKKHFEVGIITNGSSQRQRAKIINTNLNNYFDTIIISEEVGLSKPDKRIFELALNKLD
VQPEDVLFVGDDLEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
>Mature_225_residues
MLFDLDDTLLNRDMAVDTLFLFVLEKCYEDVSDTVKNNMLRKFKEYDKREYGMSDKAIVLESLFDEFPPKYRLQRNYIQD
FWNKNFPKCFSIDKNTIHFLHHIKKHFEVGIITNGSSQRQRAKIINTNLNNYFDTIIISEEVGLSKPDKRIFELALNKLD
VQPEDVLFVGDDLEKDIAGPQNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=116, Percent_Identity=34.4827586206897, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790833, Length=120, Percent_Identity=37.5, Blast_Score=88, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571108, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45552117, Length=129, Percent_Identity=27.1317829457364, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 26482; Mature: 26482

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDLDDTLLNRDMAVDTLFLFVLEKCYEDVSDTVKNNMLRKFKEYDKREYGMSDKAIVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ESLFDEFPPKYRLQRNYIQDFWNKNFPKCFSIDKNTIHFLHHIKKHFEVGIITNGSSQRQ
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECCCCHHH
RAKIINTNLNNYFDTIIISEEVGLSKPDKRIFELALNKLDVQPEDVLFVGDDLEKDIAGP
HHHHHHCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCC
QNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
CCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure
MLFDLDDTLLNRDMAVDTLFLFVLEKCYEDVSDTVKNNMLRKFKEYDKREYGMSDKAIVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ESLFDEFPPKYRLQRNYIQDFWNKNFPKCFSIDKNTIHFLHHIKKHFEVGIITNGSSQRQ
HHHHHHCCCHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHEEEEEECCCCHHH
RAKIINTNLNNYFDTIIISEEVGLSKPDKRIFELALNKLDVQPEDVLFVGDDLEKDIAGP
HHHHHHCCCHHHHHHEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCHHHHCCCC
QNANIKGVWFNPQKIKNTTKIQPYAEINTLDSLLSYVTPQYFFNK
CCCCEEEEEECHHHHCCCCCCCCHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]