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The map label for this gene is nhoA [H]

Identifier: 222096232

GI number: 222096232

Start: 2528138

End: 2528905

Strand: Reverse

Name: nhoA [H]

Synonym: BCQ_2572

Alternate gene names: 222096232

Gene position: 2528905-2528138 (Counterclockwise)

Preceding gene: 222096233

Following gene: 222096231

Centisome position: 48.5

GC content: 31.9

Gene sequence:

>768_bases
ATGACAAGTCTACAACATAAGCTTTTTACAAGATTGAATCTTGCAAAGCGTAATAAAGTGAAGTTTGAAGAATTAAATAC
AATTCTTTTTGCATTTGCACACACTATACCATTTGAGAATTTAGATGTTATAGCAAGTAACACGAATACAATTACTATGG
AAAATTTACAGAATAAAATTTTAAGCAGATCCCGCGGTGGACTTTGTTATGAATTAAATACGCTTTTTTATTACTTTTTA
AAAGATTGTGGTTATGATGTACAACTCGCATTAGGTACCGTATATAAAAATGATATAAACGCATGGGCACTTGAGAATGG
ACATATAACGATTATTCTAAATTATGATAAAGCACGATACGTAATTGATGTAGGTATTGCTTCATTAGTACCTCTAGTCC
CGGTACCTTTTACTAGTGAGCCTGTTTCTTCTAAAAATGGTACGTATCGAGTGATACGAAAAGATACGAGTAAAGGGAAT
TACGTTCTAGAAAGAAAAGATACGAATGGTGAGTGGAAAGTGTGTCATGCTTTTTATAATCGTATCATTGATGAGGCAGT
AGTAAATGATGTTCAAAAAAGAGTAATAGAAGATGAGAAATCTATTTTTAATAAAGGACCGATTGCAGTCAAATTGACGG
AATCTGGCCATGTCTCTTTAACAAATACTAGTTTAACTACAATGATTCACGGTGAAAAAACGAAACGTGAAGTTACAGAA
GAGCAATATAGAGATCTTTTATATACTTTATTTGCTATTGAGTTATGA

Upstream 100 bases:

>100_bases
TACCGGTACAGTTAAACGAAATGTACATTGTTTCAGTACCCCATCAAAATTACAATCAGCATATACTAGTTTAACTTATA
CATTTTAAGGGGTGCTGACT

Downstream 100 bases:

>100_bases
TAACGCGAATAGCTAGCCGGTTCTGAATAAGAACCGGCTATTTTATTAATTTAATTTAAAACAACTATTAAAGTTTGATT
TTCTTAATAGATATAATACA

Product: N-hydroxyarylamine o-acetyltransferase

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTSLQHKLFTRLNLAKRNKVKFEELNTILFAFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFL
KDCGYDVQLALGTVYKNDINAWALENGHITIILNYDKARYVIDVGIASLVPLVPVPFTSEPVSSKNGTYRVIRKDTSKGN
YVLERKDTNGEWKVCHAFYNRIIDEAVVNDVQKRVIEDEKSIFNKGPIAVKLTESGHVSLTNTSLTTMIHGEKTKREVTE
EQYRDLLYTLFAIEL

Sequences:

>Translated_255_residues
MTSLQHKLFTRLNLAKRNKVKFEELNTILFAFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFL
KDCGYDVQLALGTVYKNDINAWALENGHITIILNYDKARYVIDVGIASLVPLVPVPFTSEPVSSKNGTYRVIRKDTSKGN
YVLERKDTNGEWKVCHAFYNRIIDEAVVNDVQKRVIEDEKSIFNKGPIAVKLTESGHVSLTNTSLTTMIHGEKTKREVTE
EQYRDLLYTLFAIEL
>Mature_254_residues
TSLQHKLFTRLNLAKRNKVKFEELNTILFAFAHTIPFENLDVIASNTNTITMENLQNKILSRSRGGLCYELNTLFYYFLK
DCGYDVQLALGTVYKNDINAWALENGHITIILNYDKARYVIDVGIASLVPLVPVPFTSEPVSSKNGTYRVIRKDTSKGNY
VLERKDTNGEWKVCHAFYNRIIDEAVVNDVQKRVIEDEKSIFNKGPIAVKLTESGHVSLTNTSLTTMIHGEKTKREVTEE
QYRDLLYTLFAIEL

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649132, Length=111, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI237649130, Length=111, Percent_Identity=27.9279279279279, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI237649128, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649126, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649124, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649122, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649119, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI42741671, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI237649009, Length=111, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI116295260, Length=112, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787736, Length=155, Percent_Identity=26.4516129032258, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 29167; Mature: 29036

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLQHKLFTRLNLAKRNKVKFEELNTILFAFAHTIPFENLDVIASNTNTITMENLQNKI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHH
LSRSRGGLCYELNTLFYYFLKDCGYDVQLALGTVYKNDINAWALENGHITIILNYDKARY
HHCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEECCCCEEEEECCCEEEEEECCCCEE
VIDVGIASLVPLVPVPFTSEPVSSKNGTYRVIRKDTSKGNYVLERKDTNGEWKVCHAFYN
EEEECHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
RIIDEAVVNDVQKRVIEDEKSIFNKGPIAVKLTESGHVSLTNTSLTTMIHGEKTKREVTE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCEEEEEEECCHHHHHHHH
EQYRDLLYTLFAIEL
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSLQHKLFTRLNLAKRNKVKFEELNTILFAFAHTIPFENLDVIASNTNTITMENLQNKI
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHHH
LSRSRGGLCYELNTLFYYFLKDCGYDVQLALGTVYKNDINAWALENGHITIILNYDKARY
HHCCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEEECCCCEEEEECCCEEEEEECCCCEE
VIDVGIASLVPLVPVPFTSEPVSSKNGTYRVIRKDTSKGNYVLERKDTNGEWKVCHAFYN
EEEECHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHH
RIIDEAVVNDVQKRVIEDEKSIFNKGPIAVKLTESGHVSLTNTSLTTMIHGEKTKREVTE
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECCEEEEEEECCHHHHHHHH
EQYRDLLYTLFAIEL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]