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The map label for this gene is moaE [H]

Identifier: 222095770

GI number: 222095770

Start: 2082290

End: 2082760

Strand: Direct

Name: moaE [H]

Synonym: BCQ_2110

Alternate gene names: 222095770

Gene position: 2082290-2082760 (Clockwise)

Preceding gene: 222095769

Following gene: 222095771

Centisome position: 39.94

GC content: 39.7

Gene sequence:

>471_bases
ATGACACATACGTATTATGAAGTAATTGATACACCTATATCAATTGAAGAAGTGACAAACAAAGTAATTCGGCGTGAGTG
TGGTGCGATTACTACTTTTATTGGCACTGTTAGAGAATTTACGAAAGGCCGACGTACGCTTTATTTAGAGTATGTAGCTT
ATAAGACGATGGCGGAGAAACAGCTTGAGAGAATTGGTACCGAAGTAGGGGAGAAATGGCCTGGAACATATGTGGCAATT
ACACATCGCATTGGTACATTACAAATTTCTGATTTGGCTGTTGTCGTTGCTGTTGCTACACCGCATCGGAAAGCTGCTTA
TGAGGCGAATGAATATATTATGGAACGTATAAAACAAATTATTCCGATATGGAAAAAAGAGTTTTGGGAAGATAGTGAGT
CGTGGATAGGCGATCAGTTAGAGAAAACAGCATATGGTAATGGCGAGCCTGGAAAGGAGATGAGAATTTGA

Upstream 100 bases:

>100_bases
AATTAACCAGCGGAAGTGAATGGCCATGGAAAGAATCGCTTCGTTCATACAAATAATAGAAAAATAGGTTGCTAATTTAT
ACAAAGATAAGAGGTGCGAA

Downstream 100 bases:

>100_bases
TTGAAGTACTATTATTTGCACATTTACAAGAAGAAGTAAGTAAGCCAGCATTACACATAGATTGTGAAAATATTACAGTC
GCGAAGCTGAAGGAAGTTCT

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIIPIWKKEFWEDSESWIGDQLEKTAYGNGEPGKEMRI

Sequences:

>Translated_156_residues
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAI
THRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIIPIWKKEFWEDSESWIGDQLEKTAYGNGEPGKEMRI
>Mature_155_residues
THTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEKQLERIGTEVGEKWPGTYVAIT
HRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQIIPIWKKEFWEDSESWIGDQLEKTAYGNGEPGKEMRI

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=39.3700787401575, Blast_Score=122, Evalue=2e-28,
Organism=Escherichia coli, GI1787003, Length=137, Percent_Identity=36.4963503649635, Blast_Score=82, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=130, Percent_Identity=33.0769230769231, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356259, Length=132, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18007; Mature: 17876

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEECCCEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
IPIWKKEFWEDSESWIGDQLEKTAYGNGEPGKEMRI
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
THTYYEVIDTPISIEEVTNKVIRRECGAITTFIGTVREFTKGRRTLYLEYVAYKTMAEK
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
QLERIGTEVGEKWPGTYVAITHRIGTLQISDLAVVVAVATPHRKAAYEANEYIMERIKQI
HHHHHHHHHHCCCCCCEEEEEECCCEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHHHHH
IPIWKKEFWEDSESWIGDQLEKTAYGNGEPGKEMRI
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]