Click here to switch to the map view.

The map label for this gene is bsaA [H]

Identifier: 222095756

GI number: 222095756

Start: 2064609

End: 2065091

Strand: Direct

Name: bsaA [H]

Synonym: BCQ_2096

Alternate gene names: 222095756

Gene position: 2064609-2065091 (Clockwise)

Preceding gene: 222095752

Following gene: 222095762

Centisome position: 39.6

GC content: 36.85

Gene sequence:

>483_bases
ATGACAATTTATGATTTTTCAGCTAAAACAATTACAGGTGAAGAAAAATCGTTAAAAGATTACGAAGGAAAAGCACTTCT
TATTGTAAATGTAGCTAGTAAATGCGGGTTTACACCGCAATATAAAGGATTACAAGAAGTATATGATAAATATAAAGAAC
AAGGGCTAGAAATACTCGGTTTCCCATGTAACCAATTCGGAGGACAAGAACCAGGTACAGAAGCAGATATTACAAGTTTT
TGTGAATTAAACTACGGCGTAAACTTCCCAATGTTTGCAAAGATTGATGTAAAAGGTGATAAGGCTCATCCTCTGTATAC
ATACATGACAGAACAAGCACCAGGTTTACTCGGTATGAAAGCAGTGAAATGGAACTTTACTAAGTTTTTAATTGGAAAAG
ACGGGAAAGTAGTAGGGCGTTTTGCTCCGCAGACGAAGCCGGTGGATTTAGAGGTTGAGATTGAGAAGGTACTTGGCGAA
TAA

Upstream 100 bases:

>100_bases
GCGCTATCATTTTAGCGTGTAAATACGTAATAAGAGCCGTATATTCACGAATGTAGTATAGTATAAACATAGAATGATAG
TGTAGAGAGGGGCAGGAACA

Downstream 100 bases:

>100_bases
CTAGGAGTTTCACTTTATTAAAAAATGCCTTAAAGAACTATTTTGTTCTTTGAGGCATTTTATTTACATTCACATTGTCA
ATATTAAATCGCTGAATGGA

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MTIYDFSAKTITGEEKSLKDYEGKALLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEADITSF
CELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE

Sequences:

>Translated_160_residues
MTIYDFSAKTITGEEKSLKDYEGKALLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEADITSF
CELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
>Mature_159_residues
TIYDFSAKTITGEEKSLKDYEGKALLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEPGTEADITSFC
ELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=46.7948717948718, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=46.7948717948718, Blast_Score=135, Evalue=2e-32,
Organism=Homo sapiens, GI15618997, Length=156, Percent_Identity=43.5897435897436, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.0916030534351, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI192455698, Length=150, Percent_Identity=36.6666666666667, Blast_Score=112, Evalue=2e-25,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=38.728323699422, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=35.2601156069364, Blast_Score=101, Evalue=2e-22,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=34.2391304347826, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI33186887, Length=179, Percent_Identity=35.195530726257, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.8342541436464, Blast_Score=87, Evalue=8e-18,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=41.9161676646707, Blast_Score=147, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=50, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=47.4683544303797, Blast_Score=160, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=45.7317073170732, Blast_Score=141, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=41.5094339622642, Blast_Score=136, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.9693251533742, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.7423312883436, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=42.1052631578947, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=43.421052631579, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193210709, Length=72, Percent_Identity=51.3888888888889, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17507603, Length=106, Percent_Identity=35.8490566037736, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=55.3459119496855, Blast_Score=189, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=55.3956834532374, Blast_Score=172, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=44.5859872611465, Blast_Score=147, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=47.8260869565217, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656767, Length=164, Percent_Identity=47.5609756097561, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=47.8260869565217, Blast_Score=143, Evalue=5e-35,
Organism=Drosophila melanogaster, GI85726443, Length=162, Percent_Identity=40.7407407407407, Blast_Score=125, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17825; Mature: 17693

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYDFSAKTITGEEKSLKDYEGKALLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILG
CEEEECCCEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
FPCNQFGGQEPGTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMK
CCCHHCCCCCCCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEE
AVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
EEEECEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure 
TIYDFSAKTITGEEKSLKDYEGKALLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILG
EEEECCCEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
FPCNQFGGQEPGTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMK
CCCHHCCCCCCCCCCCHHHEEEECCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEE
AVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
EEEECEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]