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The map label for this gene is gntR [H]

Identifier: 222095727

GI number: 222095727

Start: 2044447

End: 2045847

Strand: Reverse

Name: gntR [H]

Synonym: BCQ_2067

Alternate gene names: 222095727

Gene position: 2045847-2044447 (Counterclockwise)

Preceding gene: 222095730

Following gene: 222095724

Centisome position: 39.24

GC content: 36.19

Gene sequence:

>1401_bases
ATGGATCTGACTATCCCATTAGTGTTACAAAATAAAACACCTATTTACTTACAAATTTACGAATATATGAAACGAGAAAT
CTCTCATGGATCACTACGTGCCGGTACACGTCTTCCTTCTCACAGAAATTTAGCTATGCAACTTAATGTAAGCCGTATTA
CAGTTGAATCCGCTTATCAACAATTACTAGCTGAAGGTTACGTAGAAAGCAAACCGAAACGCGGGATTTTTGTTGCGGAA
GTAGATATTGATGTCATTCAAAAGAAACAACAAATTGCGTCAAGCAGTACTAACAATAAAGAAAAAGAACAATATGATTA
TGATTGTAGTCAAGGACTTATTGATCAAAAAGCTTTTCCGATAACAAACTGGAAAAGAGCGTTACACGAAACTTTATTTC
AGTATGAAAATGAATTATTTGCTAAAGAAGATCCACAAGGTGAGCTCGTTCTACGAGAACATATTTCAAAGTATTTATAT
CATGCTCGCGGGGTACATTCTTCACCTGATCAAATTATTATTGGAGCAGGTACGCAGCCTCTTCTTTGGCTACTCCTTCA
ACTACTTGGTTCAAAAAAAGAATACGGAATCGAAAATCCTGGATTTCACCGTATACCTGCTATGATTCAAAGTTGTGGCC
TTCCTGTTCACCCGATCCCTTTAGACGATAAAGGGATTCATATTTCCGCTTTACGTGAATCCGGTTCCAATGTGGCATAT
GTCACTCCATCTCACCAATTTCCACTCGGAATCATTATGCCATTATCTAGAAGACTCGAGTTATTAAAATGGGCGAATGA
TTGTAATGGTTATATTATTGAAGATGATTACGACGGGGAATTTCGCTATATAGGAAAACCTATTCCTTCTTTACAAGGGC
TAGATTCAAATGAACGTGTTATTTATATGGGAACTTTCTCGAAATCTTTTTTACCTTCTTTACGAATGGGATATATCGTT
TTACCACCTCATCTTTTAAAAGTCTATAAAGAACTTGGTGGTATGTTTAAACAAACTGTCTCTACAATGCAACAACTTAC
CTTCGCCACCTTTATTCAAAATGGGGATTGGGAACGTCATATTAACCGAAGTCGTACGTTATATAAAAGAAAACATATTT
CTTTAATTAAATCTATTAAAAGCGAAATGGGAAATAACGTGCATATACTCGGTGAACAATCCGGGCTTCATATTGTACTT
CACGTTCATAACGGGATGAATGAACAAGAACTTATTCATGCAGCTGCAAAAGAACGTATTAAGTTATACCCTCTCTCCAC
ATATGATTCTGTTTATAATGTGAGGGAGGAGTCATATGTATTGCTCGGTTTTGGCAGTATTCGAGAGGAATGTATTGAAA
CTGTTGTCAAATTACTGAAAAAAGCGTGGTTCCCTAAATAA

Upstream 100 bases:

>100_bases
TTCTAAATGTTATATCATCATTATAGAAAGCGACTGCCCTTAGTTTAAGTGACAGTTCTATTCTTTTTTATAAGGCCAGT
ATAAAAAGGAGCGTCTACAA

Downstream 100 bases:

>100_bases
AAATAGCTCCACGCAAGTTATACTTACGTGGAGCTATTTTTATGCACTATTTTTCTGATCTCATTGCCCTTCCCGGACGT
TTGACACCAGTTGTTTCTGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MDLTIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASSSTNNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGSNVAY
VTPSHQFPLGIIMPLSRRLELLKWANDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQNGDWERHINRSRTLYKRKHISLIKSIKSEMGNNVHILGEQSGLHIVL
HVHNGMNEQELIHAAAKERIKLYPLSTYDSVYNVREESYVLLGFGSIREECIETVVKLLKKAWFPK

Sequences:

>Translated_466_residues
MDLTIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASSSTNNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGSNVAY
VTPSHQFPLGIIMPLSRRLELLKWANDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQNGDWERHINRSRTLYKRKHISLIKSIKSEMGNNVHILGEQSGLHIVL
HVHNGMNEQELIHAAAKERIKLYPLSTYDSVYNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
>Mature_466_residues
MDLTIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQQLLAEGYVESKPKRGIFVAE
VDIDVIQKKQQIASSSTNNKEKEQYDYDCSQGLIDQKAFPITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLY
HARGVHSSPDQIIIGAGTQPLLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGSNVAY
VTPSHQFPLGIIMPLSRRLELLKWANDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERVIYMGTFSKSFLPSLRMGYIV
LPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQNGDWERHINRSRTLYKRKHISLIKSIKSEMGNNVHILGEQSGLHIVL
HVHNGMNEQELIHAAAKERIKLYPLSTYDSVYNVREESYVLLGFGSIREECIETVVKLLKKAWFPK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787710, Length=438, Percent_Identity=25.7990867579909, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=27.012987012987, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53335; Mature: 53335

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQ
CCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHEEEHHHHHH
QLLAEGYVESKPKRGIFVAEVDIDVIQKKQQIASSSTNNKEKEQYDYDCSQGLIDQKAFP
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCCHHCCCCCCCCCC
ITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLYHARGVHSSPDQIIIGAGTQP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH
LLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGSNVAY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEE
VTPSHQFPLGIIMPLSRRLELLKWANDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERV
ECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCEE
IYMGTFSKSFLPSLRMGYIVLPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQNGDWERH
EEEECCCHHHCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
INRSRTLYKRKHISLIKSIKSEMGNNVHILGEQSGLHIVLHVHNGMNEQELIHAAAKERI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCE
KLYPLSTYDSVYNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
EEEECCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLTIPLVLQNKTPIYLQIYEYMKREISHGSLRAGTRLPSHRNLAMQLNVSRITVESAYQ
CCCEEEEEECCCCCEEEHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEHEEEHHHHHH
QLLAEGYVESKPKRGIFVAEVDIDVIQKKQQIASSSTNNKEKEQYDYDCSQGLIDQKAFP
HHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHCCCCHHCCCCCCCCCC
ITNWKRALHETLFQYENELFAKEDPQGELVLREHISKYLYHARGVHSSPDQIIIGAGTQP
CHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHH
LLWLLLQLLGSKKEYGIENPGFHRIPAMIQSCGLPVHPIPLDDKGIHISALRESGSNVAY
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEE
VTPSHQFPLGIIMPLSRRLELLKWANDCNGYIIEDDYDGEFRYIGKPIPSLQGLDSNERV
ECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCEE
IYMGTFSKSFLPSLRMGYIVLPPHLLKVYKELGGMFKQTVSTMQQLTFATFIQNGDWERH
EEEECCCHHHCCHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
INRSRTLYKRKHISLIKSIKSEMGNNVHILGEQSGLHIVLHVHNGMNEQELIHAAAKERI
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCE
KLYPLSTYDSVYNVREESYVLLGFGSIREECIETVVKLLKKAWFPK
EEEECCHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]