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The map label for this gene is namA [H]

Identifier: 222095683

GI number: 222095683

Start: 2003267

End: 2004304

Strand: Reverse

Name: namA [H]

Synonym: BCQ_2023

Alternate gene names: 222095683

Gene position: 2004304-2003267 (Counterclockwise)

Preceding gene: 222095690

Following gene: 222095680

Centisome position: 38.44

GC content: 37.57

Gene sequence:

>1038_bases
ATGAATTACAAACTTTTTTCACCTTATACAATTAAAGACGTTACATTAAAAAACCGGATTGTTATGTCACCTATGTGCAT
GTATTCATCGAAAAACGAGGATGGCCAAATAACGAATTTCCATCTTATTCATTATGGAACAAGAGCTGCTGGTCAAGTTG
GTTTAGTTATGATTGAAGCAACAGCCGTGTTACCTGAAGGTCGAATTTCAAATAAAGACTTAGGCATTTGGGATGACAGT
TTAATTGAAGGCTTACATAAAGCGACAACTTTTATACACGATAATGGTGCAAAAGCTGCCATTCAACTCGCTCATGCTGG
AAGAAAAGCAGAATTAGAAACAGATGCGTTAGCTCCTTCAGCCATTCCATTTAATGAAACAATGAAAATGCCAATAGAAA
TGAGCAAACACCAAATTAAAGATACTGTATTAGCTTTTCAGCAAGCTGCAGTACGATCCAAACAAGCTGGATTTGACGTT
ATTGAAATACACGGTGCTCACGGTTATCTTATTAATGAATTTCTTTCTCCACTTACCAATAAGCGGACTGATGAATATGG
TGGTTCACCTGAAAATCGATATCGTTTCTTACGCGAAATCATTGAATCGATAAATGAAGTTTGGAACGGACCGCTATTTG
TTCGTATTTCAGCAAATGATTATCATCCTGACGGGTTAACAGTTCAAGATTATGTACAATATACAAAATGGATGAAAGAA
CAAGGAGTAGATTTAATCGATTGTAGCTCTGGGGCTGTTGTACCTGCGCGCATCGATGTTTACCCTGGGTATCAAGTACA
ATATGCTAAACATATTAAAGAGCATGCTAACATTGCAACTGGTGCAGTTGGATTGATTACGACCGGGGCACAAGCAGAGC
AAATTTTAAATAATAACGAAGCAGATTTAATTTTTATCGGACGTGAGTTACTTCGCAATCCTTACTTCCCAAGAATAGCC
GCCAATGAACTTGGCTTTGAATTAGAAGAACCGTATCAATACGAGCGAGCGCCTGGGAAAATCAGTACAAATAAATAA

Upstream 100 bases:

>100_bases
TGTAACACGAATAGACAAAATTTTTCGTATAAGCGTTTTATTCGAGAAACAAAAACGAGAATGATACAATGTAAGAAAAT
TCAATCTAGGAGGCTATTGG

Downstream 100 bases:

>100_bases
AACCGAGAAGCTCTTCTTCTCGGTTTTATTTATTCTATCGTTGTAATTTCATTCGAATTATAAATGTGGATACCTGATTC
TTCTCGCAATGCAGTTATAT

Product: nadph dehydrogenase nama

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDV
IEIHGAHGYLINEFLSPLTNKRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPYQYERAPGKISTNK

Sequences:

>Translated_345_residues
MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDV
IEIHGAHGYLINEFLSPLTNKRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPYQYERAPGKISTNK
>Mature_345_residues
MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDS
LIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPSAIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDV
IEIHGAHGYLINEFLSPLTNKRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELEEPYQYERAPGKISTNK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=320, Percent_Identity=29.6875, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787939, Length=234, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI72001454, Length=251, Percent_Identity=31.8725099601594, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559802, Length=262, Percent_Identity=29.7709923664122, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17540738, Length=257, Percent_Identity=30.7392996108949, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565138, Length=181, Percent_Identity=32.0441988950276, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559804, Length=173, Percent_Identity=35.8381502890173, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=337, Percent_Identity=28.7833827893175, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17564188, Length=174, Percent_Identity=34.4827586206897, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6325086, Length=220, Percent_Identity=32.7272727272727, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=217, Percent_Identity=34.1013824884793, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38605; Mature: 38605

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEA
CCCEECCCEEEEEEEECCEEEECHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCCHHHCCCC
AIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDVIEIHGAHGYLINEFLSPLTN
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPYQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNYKLFSPYTIKDVTLKNRIVMSPMCMYSSKNEDGQITNFHLIHYGTRAAGQVGLVMIEA
CCCEECCCEEEEEEEECCEEEECHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLPEGRISNKDLGIWDDSLIEGLHKATTFIHDNGAKAAIQLAHAGRKAELETDALAPS
EEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCCHHHCCCC
AIPFNETMKMPIEMSKHQIKDTVLAFQQAAVRSKQAGFDVIEIHGAHGYLINEFLSPLTN
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDEYGGSPENRYRFLREIIESINEVWNGPLFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGVDLIDCSSGAVVPARIDVYPGYQVQYAKHIKEHANIATGAVGLITTGAQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHCCCCEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELEEPYQYERAPGKISTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA