Click here to switch to the map view.

The map label for this gene is iolS [H]

Identifier: 222095659

GI number: 222095659

Start: 1982886

End: 1983821

Strand: Direct

Name: iolS [H]

Synonym: BCQ_1999

Alternate gene names: 222095659

Gene position: 1982886-1983821 (Clockwise)

Preceding gene: 222095657

Following gene: 222095660

Centisome position: 38.03

GC content: 34.51

Gene sequence:

>936_bases
ATGAAGTATACAAAATTGCAAAAGGCAGGACTACATATTTCAAAGTTGGGGTTAGGAACAAACGCTGTAGGGGGACATAA
TTTATATGCTGATGTGAATGAGGAAGAAGGAAAACAATTAATAGAAGAAGCTATGGGGCAAGGGATTACCTTTATTGATA
CAGCAGATTCATACGGTTTCGGCAGATCAGAAGAATTGGTAGGGGAAGTATTGAAGGGAAAACGCCACGAAGTTGTACTT
GCTACAAAAGGTGGAATACAACCGTTATTAAATGGAGAGGTTTATATGAATAATGAACCGAGCTATTTAAGAAATGCTGT
AGAAAATAGCTTAAGAAGATTACAAACTGATTATATTGATTTATATTATTTACATTTTACAAACCCAGAAACAAGTTACA
TAGATTCAATTGGAGAACTTACTCGCCTAAAAGAAGAAGGGAAAATTCGTTCAATTGGAATATCTAACGTAAACGTAGAG
CAATTAAAAGAAGCGAATCAGCATGGGCACATAGATGTTGTACAATCACCGTATAATATGTTAGATCGTACTGCTGGGCA
AGAACTTTTGCCATATTGTATAGAATCAGGTATTTCATTTATTCCTTACGGGCCTCTTGCTTTTGGGATACTAGGTGGTA
AATATACAGAAGATTTCAAATTGAATAAAGGAGATTGGCGTCAAAGTGTAAATCTATTTGAAGAGAATACATATAAGAGC
AACTTTAAGAAAGTTGAAAAGTTAAAAGACATAGCTAAAGAAAAGGATCTCGAATTATCACATTTAGCTTTAGCATGGTT
ATTAAACCAAAAAGGAATTGATACTGTTATTCCTGGTGGGAAACGAGCGGAGCAAATAAGAGAAAGTGTAAGAGCGGTGG
AAGTTTCATTGAATGAAGATGTCATGAAAGAGATTGAATCTATTTTAGAAGATTAG

Upstream 100 bases:

>100_bases
CTGCTCGTATAAGTTAATATATTTGCACTATAACATATAAAGTGATATATTTCTATTGTTCGAATATATTCGAACAATAG
AAATATAGGGGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTGAAAGGAGGGATAATTCCCTCCTTTTATATAAAAGGAGAAGATTTAAATGAAAAGAGTACTAGCTGTATTCTTTACAA
TCATGTTTATGATCGGTACA

Product: oxidoreductase, aldo/keto reductase family

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFIDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYMNNEPSYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGQELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNKGDWRQSVNLFEENTYKS
NFKKVEKLKDIAKEKDLELSHLALAWLLNQKGIDTVIPGGKRAEQIRESVRAVEVSLNEDVMKEIESILED

Sequences:

>Translated_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFIDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYMNNEPSYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGQELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNKGDWRQSVNLFEENTYKS
NFKKVEKLKDIAKEKDLELSHLALAWLLNQKGIDTVIPGGKRAEQIRESVRAVEVSLNEDVMKEIESILED
>Mature_311_residues
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFIDTADSYGFGRSEELVGEVLKGKRHEVVL
ATKGGIQPLLNGEVYMNNEPSYLRNAVENSLRRLQTDYIDLYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVE
QLKEANQHGHIDVVQSPYNMLDRTAGQELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNKGDWRQSVNLFEENTYKS
NFKKVEKLKDIAKEKDLELSHLALAWLLNQKGIDTVIPGGKRAEQIRESVRAVEVSLNEDVMKEIESILED

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=330, Percent_Identity=28.7878787878788, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4504825, Length=328, Percent_Identity=28.6585365853659, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=28.0120481927711, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI27436962, Length=332, Percent_Identity=27.710843373494, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=27.4096385542169, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI223718702, Length=276, Percent_Identity=29.3478260869565, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41327764, Length=276, Percent_Identity=31.1594202898551, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI41152114, Length=276, Percent_Identity=30.0724637681159, Blast_Score=85, Evalue=8e-17,
Organism=Escherichia coli, GI1788070, Length=327, Percent_Identity=34.8623853211009, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=32.2884012539185, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=28.9398280802292, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1789375, Length=310, Percent_Identity=28.0645161290323, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788081, Length=254, Percent_Identity=27.9527559055118, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787674, Length=303, Percent_Identity=24.7524752475248, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082198, Length=163, Percent_Identity=31.9018404907975, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=316, Percent_Identity=25, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561298, Length=318, Percent_Identity=24.2138364779874, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71998625, Length=301, Percent_Identity=25.9136212624585, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564128, Length=326, Percent_Identity=24.5398773006135, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=334, Percent_Identity=27.5449101796407, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=26.6871165644172, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=26.2798634812287, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=321, Percent_Identity=26.1682242990654, Blast_Score=96, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=222, Percent_Identity=24.7747747747748, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646155, Length=309, Percent_Identity=28.1553398058252, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640980, Length=350, Percent_Identity=23.1428571428571, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45549126, Length=350, Percent_Identity=23.1428571428571, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=32.8888888888889, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34928; Mature: 34928

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFIDTADSYGF
CCCCHHHHHCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCC
GRSEELVGEVLKGKRHEVVLATKGGIQPLLNGEVYMNNEPSYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGQELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNKGDWRQSVNLFEENTYKS
HHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKDIAKEKDLELSHLALAWLLNQKGIDTVIPGGKRAEQIRESVRAVEVSLNED
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
VMKEIESILED
HHHHHHHHHCC
>Mature Secondary Structure
MKYTKLQKAGLHISKLGLGTNAVGGHNLYADVNEEEGKQLIEEAMGQGITFIDTADSYGF
CCCCHHHHHCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCC
GRSEELVGEVLKGKRHEVVLATKGGIQPLLNGEVYMNNEPSYLRNAVENSLRRLQTDYID
CCCHHHHHHHHCCCCCEEEEEECCCCCEEECCEEEECCCHHHHHHHHHHHHHHHHHCCEE
LYYLHFTNPETSYIDSIGELTRLKEEGKIRSIGISNVNVEQLKEANQHGHIDVVQSPYNM
EEEEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCCCCCCEEEECCCHHH
LDRTAGQELLPYCIESGISFIPYGPLAFGILGGKYTEDFKLNKGDWRQSVNLFEENTYKS
HHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NFKKVEKLKDIAKEKDLELSHLALAWLLNQKGIDTVIPGGKRAEQIRESVRAVEVSLNED
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
VMKEIESILED
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]