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The map label for this gene is yqjC [H]

Identifier: 222095562

GI number: 222095562

Start: 1883527

End: 1883946

Strand: Direct

Name: yqjC [H]

Synonym: BCQ_1902

Alternate gene names: 222095562

Gene position: 1883527-1883946 (Clockwise)

Preceding gene: 222095561

Following gene: 222095563

Centisome position: 36.12

GC content: 37.86

Gene sequence:

>420_bases
ATGAAAAAAACAATTGATCACATCGGCATCGCAGTGCGCGATATAGATAGTACGATACGTTTTTATGAAAAGGTATTGTT
AGGAACATTAATAGATCGTTACGTAAGTGAGGCACCTGGTGTTGAAAGCGAAGTAGCCATTCTTGAAGTAGATGGAGATA
GAATCGAATTACTTGCACCGACGAATAATACGACGTCGCCAATTGCCAGATTCATTAAACAAAAAGGTAAAGGTGTACAT
CATGTTGCATATCGAGTAGATGATTTAGATGTAGCTTTAGAAGAATTGAAAGAACAAGGTATTCGAACGTTAGAGCATAC
ACTTCGAATGAATAAACACGGCAGAAGACTAATCTATCTTAACCCAGCGGATACAGAGGGAACAATCATAGAGTATTGTG
ATTATCCGGAAGAGAAATAG

Upstream 100 bases:

>100_bases
ATAAGAAAATAGGTTAAATAAAAAAGTTATAGAACTTGTTTCTATAACTTTTTTTGTTACTATTAATAATGAGAGAAAAT
AAAGTAGTAGGGGAAATAAA

Downstream 100 bases:

>100_bases
AAAAAAGATATTTTTAAAAAGATGTTACGTAATAAAGTAACATCTTTTTATTTATGTATTTCACATTTTCTTCACAAATG
ATTCACGATAACTTTTCTTC

Product: glyoxalase family protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKKTIDHIGIAVRDIDSTIRFYEKVLLGTLIDRYVSEAPGVESEVAILEVDGDRIELLAPTNNTTSPIARFIKQKGKGVH
HVAYRVDDLDVALEELKEQGIRTLEHTLRMNKHGRRLIYLNPADTEGTIIEYCDYPEEK

Sequences:

>Translated_139_residues
MKKTIDHIGIAVRDIDSTIRFYEKVLLGTLIDRYVSEAPGVESEVAILEVDGDRIELLAPTNNTTSPIARFIKQKGKGVH
HVAYRVDDLDVALEELKEQGIRTLEHTLRMNKHGRRLIYLNPADTEGTIIEYCDYPEEK
>Mature_139_residues
MKKTIDHIGIAVRDIDSTIRFYEKVLLGTLIDRYVSEAPGVESEVAILEVDGDRIELLAPTNNTTSPIARFIKQKGKGVH
HVAYRVDDLDVALEELKEQGIRTLEHTLRMNKHGRRLIYLNPADTEGTIIEYCDYPEEK

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=131, Percent_Identity=35.1145038167939, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17506387, Length=128, Percent_Identity=32.8125, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15818; Mature: 15818

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIDHIGIAVRDIDSTIRFYEKVLLGTLIDRYVSEAPGVESEVAILEVDGDRIELLAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
TNNTTSPIARFIKQKGKGVHHVAYRVDDLDVALEELKEQGIRTLEHTLRMNKHGRRLIYL
CCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
NPADTEGTIIEYCDYPEEK
CCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MKKTIDHIGIAVRDIDSTIRFYEKVLLGTLIDRYVSEAPGVESEVAILEVDGDRIELLAP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
TNNTTSPIARFIKQKGKGVHHVAYRVDDLDVALEELKEQGIRTLEHTLRMNKHGRRLIYL
CCCCHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
NPADTEGTIIEYCDYPEEK
CCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]