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The map label for this gene is matE [H]

Identifier: 222095444

GI number: 222095444

Start: 1750223

End: 1751632

Strand: Direct

Name: matE [H]

Synonym: BCQ_1784

Alternate gene names: 222095444

Gene position: 1750223-1751632 (Clockwise)

Preceding gene: 222095443

Following gene: 222095446

Centisome position: 33.57

GC content: 36.03

Gene sequence:

>1410_bases
TTGAAACCACCTACAAATAACAATAAAGAAGGTGCGGAGTCACATAAGTTAGAAAGTGAGAGTAAACCGATTTGGAAATC
GATGTCCATGTTTTTAGTACCGTTACTATTAAGTAATGTACTACAATCAGTTGGACAATTATTCGGTATGGTAGTAGTAG
GAAGATGGCTTGGAGTGAATGATTTAGCGGCCATATCGGCATTCTTTCCTCTATTTTTCTTACTCGTTTCATTTGTAATT
GGTATTGGTTCAGGTAGTTCTATTTTAATAGGTCAGGCGTTTGGGGCAAAAAACGAAGATCGTTTAAAAGCGATTGTTGG
TACGACGCTAACATTTACCTTTATTATTGGAGTTGTGTTAGCGATAGTAGGTAGTATTTTTGCAATGGATATTATGCGCC
TTATGGGGACGCCAGAAAATATTATTGAAATAAGTGTACATTATGCACGTATTTTATTTATATCGATGCCAATCTTATTT
TTATATTTCGCATACACAACGTTTATGAGAGGTACAGGAGATTCTAAAACGCCATTTTACTTTTTAATTGTAAGTACAGC
GCTAAATATGATCTTATTACCAATCCTTATTTTTGGATGGTTAGGTGCTCCAAAATTAGATGTGTATGGAGCAGCCTATG
CTTCTGTTATATCTACAGTTATTACGTTTATTGTCATGTTAGTGTATTTAAAGAAAAAAAATCACCCACTACAATTAGAT
AGTACGGTAAGGAAATATCTTCGAATGGATTGGGGGTTATTAAAGCTTTTACTACGACTTGGTATTCCAGCGAGTATTAA
TATGATATTAGTTTCATTATCAGAAATTGCGGTAATCGCGTTTGTAAATCGTTACGGTTCGGATGCAACAGCAGCTTATG
GCGTTGTGAACCAAGTTGCAAGTTATGTGCAAATGCCAGCAGTTAGTCTTGGTATTACAGTCTCCATTTTTGCTGCCCAA
TCAATTGGTGCGAATCAATTTGATCGATTGCAGAAAGTTGTGAAGGCCGGAATTATTATGAACTACGTCATCGGTGGTGT
GCTAATATCTCTCATTTACTTGTTCTCAAGAGACATTCTATCACTATTTTTAACGAGTCAAACTACAATTGAAATTGCTC
ATAGCCTAGTTATGATTACATTATGGAGTTATTTAATTTTCGGGCATGCGCAAATTATTAGTGCGACAATGCGAGCAAGC
GGTACAGTATTATGGCCAACTGTTATTGGCGTCGTATCAATTTGGCTTGTTGAAGTACCTGTAGCGTATTACCTTTCTTA
CCATACAAGCCTTGGCATAGAAGGCATATGGATTGGATACCCAGCAGCATTTATTGTTAGCTTAATACTACAATATGCAT
ATTATAAGCTTTCATGGCAGAAGAAACGAATTACACGATTAGTGAGTTAA

Upstream 100 bases:

>100_bases
AATATAGGGACAAGAAAATGAATAGAAGCACATCGTTATAACAACTATACAAAGAGATAGAAGTTGAAAAACAGATTTTT
AATAAAAGGAGAAATGAAAT

Downstream 100 bases:

>100_bases
ACACTAAAAATGTCCCTAAGTTATTATACTTAGGGACATTTTTTATAAGTGCAGATTTACAAATAGCTTTTTAAAGTAAT
ATCAAAATGTTGTCTAATGA

Product: Na+ driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MKPPTNNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPILF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWGLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS

Sequences:

>Translated_469_residues
MKPPTNNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPILF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWGLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS
>Mature_469_residues
MKPPTNNNKEGAESHKLESESKPIWKSMSMFLVPLLLSNVLQSVGQLFGMVVVGRWLGVNDLAAISAFFPLFFLLVSFVI
GIGSGSSILIGQAFGAKNEDRLKAIVGTTLTFTFIIGVVLAIVGSIFAMDIMRLMGTPENIIEISVHYARILFISMPILF
LYFAYTTFMRGTGDSKTPFYFLIVSTALNMILLPILIFGWLGAPKLDVYGAAYASVISTVITFIVMLVYLKKKNHPLQLD
STVRKYLRMDWGLLKLLLRLGIPASINMILVSLSEIAVIAFVNRYGSDATAAYGVVNQVASYVQMPAVSLGITVSIFAAQ
SIGANQFDRLQKVVKAGIIMNYVIGGVLISLIYLFSRDILSLFLTSQTTIEIAHSLVMITLWSYLIFGHAQIISATMRAS
GTVLWPTVIGVVSIWLVEVPVAYYLSYHTSLGIEGIWIGYPAAFIVSLILQYAYYKLSWQKKRITRLVS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=456, Percent_Identity=20.6140350877193, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321821, Length=374, Percent_Identity=21.1229946524064, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51730; Mature: 51730

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]