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The map label for this gene is slt [H]

Identifier: 222095384

GI number: 222095384

Start: 1696195

End: 1696974

Strand: Direct

Name: slt [H]

Synonym: BCQ_1724

Alternate gene names: 222095384

Gene position: 1696195-1696974 (Clockwise)

Preceding gene: 222095381

Following gene: 222095385

Centisome position: 32.53

GC content: 39.1

Gene sequence:

>780_bases
ATGGTAGTTGGAAATATAGTAAAAGAAGTACTTGCATATAAAAAAGGACAGTTTCAGCAAAAGTTAAGTAGTCCGCAGGC
GTTCGTTAGTAGTAGGTTTCAAGAGAAGTTGCAAAGCGAGCCTATGAAGGAAACGAAGGCTACTACGCAGCCGGCAAAAG
TAGAGGATATGAGTCAGCCGGTACAATCTACGAAAATAGAAACGCTCGTTAATAAAGGTGATTCTAGTAAAGTAGAGGAA
GCGAGTAAGCCGGAAGAAAAGTCTGAAACGAAGAAAGTCGATGAAGTGCAAGTTGCGCAAAAAGAGTTTGAACGACGTTT
CCCGGAAACGAAAAATGAGGCTGTTGATACGTGGGGATTAACGAAGAAGTATAATATTCAAAAAATACGTTCTTCAAATG
AAGGGAAGTATGAGGATATTATAGATAGAGTAAGTCGTACATACGGAATTCCGAAAACGTTAATTCAAAAAATGATTGAA
GTAGAGTCTGATTTTAATCCGAAAACGGTGTCGCATGCAGGGGCGATGGGCCTTATGCAGCTTATGCCGGCGAATGTAAA
AGAGATGGGTATAAAAAATCCATTTTCACCAGCTGAAAGTATTGAAGGCGGCGTGAAAGAGTTAAGCGGTTATTTAAAGA
AAAATAACGGTGACTTAGTATTGGCGCTCGCTTCTTATAATGCTGGCCCTGGTAATGTGAGAAAGTACGGAGGCGTACCT
CCATTTAAAGAAACGCAAGGATATATTAAAAAAATATTAAATATCGACGTTTCAAAATAA

Upstream 100 bases:

>100_bases
TAGCCGTTTTTTTATTACAATATAATTGCAAAGGATTATTGCAAACTTTACGAAAAAACTCTAATATTAGATTATCTTTG
TTTACCGAAAAGGTGATATT

Downstream 100 bases:

>100_bases
GAGATTTCATTATATAGAGAGAACATGAAATTTTCGTGAACATGATATGGGAGTTGGCTAGATTTGAAATTACAAGATGA
TATTCCGTTAACAATTTATT

Product: soluble lytic murein transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVVGNIVKEVLAYKKGQFQQKLSSPQAFVSSRFQEKLQSEPMKETKATTQPAKVEDMSQPVQSTKIETLVNKGDSSKVEE
ASKPEEKSETKKVDEVQVAQKEFERRFPETKNEAVDTWGLTKKYNIQKIRSSNEGKYEDIIDRVSRTYGIPKTLIQKMIE
VESDFNPKTVSHAGAMGLMQLMPANVKEMGIKNPFSPAESIEGGVKELSGYLKKNNGDLVLALASYNAGPGNVRKYGGVP
PFKETQGYIKKILNIDVSK

Sequences:

>Translated_259_residues
MVVGNIVKEVLAYKKGQFQQKLSSPQAFVSSRFQEKLQSEPMKETKATTQPAKVEDMSQPVQSTKIETLVNKGDSSKVEE
ASKPEEKSETKKVDEVQVAQKEFERRFPETKNEAVDTWGLTKKYNIQKIRSSNEGKYEDIIDRVSRTYGIPKTLIQKMIE
VESDFNPKTVSHAGAMGLMQLMPANVKEMGIKNPFSPAESIEGGVKELSGYLKKNNGDLVLALASYNAGPGNVRKYGGVP
PFKETQGYIKKILNIDVSK
>Mature_259_residues
MVVGNIVKEVLAYKKGQFQQKLSSPQAFVSSRFQEKLQSEPMKETKATTQPAKVEDMSQPVQSTKIETLVNKGDSSKVEE
ASKPEEKSETKKVDEVQVAQKEFERRFPETKNEAVDTWGLTKKYNIQKIRSSNEGKYEDIIDRVSRTYGIPKTLIQKMIE
VESDFNPKTVSHAGAMGLMQLMPANVKEMGIKNPFSPAESIEGGVKELSGYLKKNNGDLVLALASYNAGPGNVRKYGGVP
PFKETQGYIKKILNIDVSK

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082441, Length=245, Percent_Identity=26.1224489795918, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 28868; Mature: 28868

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVGNIVKEVLAYKKGQFQQKLSSPQAFVSSRFQEKLQSEPMKETKATTQPAKVEDMSQP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHH
VQSTKIETLVNKGDSSKVEEASKPEEKSETKKVDEVQVAQKEFERRFPETKNEAVDTWGL
HHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
TKKYNIQKIRSSNEGKYEDIIDRVSRTYGIPKTLIQKMIEVESDFNPKTVSHAGAMGLMQ
CCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LMPANVKEMGIKNPFSPAESIEGGVKELSGYLKKNNGDLVLALASYNAGPGNVRKYGGVP
HCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
PFKETQGYIKKILNIDVSK
CHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVVGNIVKEVLAYKKGQFQQKLSSPQAFVSSRFQEKLQSEPMKETKATTQPAKVEDMSQP
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHH
VQSTKIETLVNKGDSSKVEEASKPEEKSETKKVDEVQVAQKEFERRFPETKNEAVDTWGL
HHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
TKKYNIQKIRSSNEGKYEDIIDRVSRTYGIPKTLIQKMIEVESDFNPKTVSHAGAMGLMQ
CCCCHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
LMPANVKEMGIKNPFSPAESIEGGVKELSGYLKKNNGDLVLALASYNAGPGNVRKYGGVP
HCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCC
PFKETQGYIKKILNIDVSK
CHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]