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The map label for this gene is panC [H]

Identifier: 222095269

GI number: 222095269

Start: 1576783

End: 1577631

Strand: Direct

Name: panC [H]

Synonym: BCQ_1609

Alternate gene names: 222095269

Gene position: 1576783-1577631 (Clockwise)

Preceding gene: 222095268

Following gene: 222095270

Centisome position: 30.24

GC content: 36.28

Gene sequence:

>849_bases
ATGAAAATCATAAATACAGTGCAAGAGATGCAGCAAATTACAAACGAACTACGTGCAAGTGGAAAAAGTATCGGTTTTGT
CCCAACGATGGGTTATTTACATGAAGGTCATGCGACTTTATTACGTAAGGCAAGAGAAGAAAATGAAATTGTAGTTTTAA
GCGTGTTTGTTAATCCGCTACAGTTTGGACCAAATGAAGATTTAGATCGATACCCTCGTGATATTGATAGAGATGAAAAT
GTAGCAAAAGAAAACAGTGTAGATTATTTATTTTATCCGAGCGTAGAAGAAATGTATCCAGCAGAACAAACGACAACAGT
AGAAGTTGTGAAGCGTACCGATGTGTTATGCGGAAAACAAAGACCTGGTCATTTCGCTGGTGTTGCGATTGTACTAATGA
AACTATTTAATATTACATTGCCAACACGTGCTTATTTCGGTATGAAAGATGCACAGCAAGTTGCTGTCATTGAAGGATTT
GTCGCTGATTTTAATATTCCGGTTACAATCGTACCGGTGGATATTGTAAGGGAAGAAGATGGATTAGCCAAAAGTTCTCG
TAACGTGTATTTATCACCAGAAGAGCGTGAAGAGGCTCTTCATTTATACCGCAGTCTATGTATAGCGAAAGAAAGAATTG
AGACAGGAGAACGTAATGCAGAAATCATTACAACTCTTGTGAAAGAGTATATTGAGACGTATACGAAAGGCACTGTAGAT
TATGCTGATTTATATGCGTATCCTTCACTACAAGTAGTGGATAAAATTGAAGGACGAATCATTTTAGCAATTGCAGTTAA
ATTTGACAATGTACGATTAATTGACAATATAACATTAACGGTTAAATAA

Upstream 100 bases:

>100_bases
AATACGTAACTGAAGTAAAGACAGGTCAATTTCCGGAAGAAAAACATTCATTCACAATGAAAGAGGAAGAATGTTTAGCG
TTATACGGAGGAAAACAATA

Downstream 100 bases:

>100_bases
GGGGGAGCATCTATGTTTCGCACAATGATGAGAGCGAAGCTACATCGCGCAACAGTAACAGAAGCAAATTTAAATTATGT
AGGTAGTATTACAATTGATG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVTIVPVDIVREEDGLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK

Sequences:

>Translated_282_residues
MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVTIVPVDIVREEDGLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK
>Mature_282_residues
MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDEN
VAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGF
VADFNIPVTIVPVDIVREEDGLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVD
YADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=41.2186379928315, Blast_Score=200, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6322046, Length=310, Percent_Identity=39.0322580645161, Blast_Score=182, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31981; Mature: 31981

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQ
CCCCCCCHHHCCCCCCCCCCCHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVTIVPVDIVREED
CCCCHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCC
GLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVD
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
YADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK
HHHHHCCCCHHHHHHCCCEEEEEEEEEECCEEEEEEEEEEEC
>Mature Secondary Structure
MKIINTVQEMQQITNELRASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPL
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCEEEEEEEECHH
QFGPNEDLDRYPRDIDRDENVAKENSVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQ
CCCCCCCHHHCCCCCCCCCCCHHHCCCCEEECCCHHHHCCCCCCHHHHHHHHHHHHCCCC
RPGHFAGVAIVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVADFNIPVTIVPVDIVREED
CCCCHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCC
GLAKSSRNVYLSPEEREEALHLYRSLCIAKERIETGERNAEIITTLVKEYIETYTKGTVD
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
YADLYAYPSLQVVDKIEGRIILAIAVKFDNVRLIDNITLTVK
HHHHHCCCCHHHHHHCCCEEEEEEEEEECCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA