Click here to switch to the map view.

The map label for this gene is resA [H]

Identifier: 222095203

GI number: 222095203

Start: 1518139

End: 1518660

Strand: Direct

Name: resA [H]

Synonym: BCQ_1543

Alternate gene names: 222095203

Gene position: 1518139-1518660 (Clockwise)

Preceding gene: 222095202

Following gene: 222095204

Centisome position: 29.12

GC content: 32.57

Gene sequence:

>522_bases
ATGAAAAAAAATCGCTTATTATTTCGCGTTATTATTCTGCTCATTTTATGTGGTGCTGTAGGATTTACACTTTATCAAGG
ATATTTCTCTAAAGAAGAGAAAATGGAAATTGGAAAAGAAGCACCTAACTTTGTTGTGACAGATTTAGAAGAAAAGAAAA
TTGAGCTAAAAGATTTTAAGGGAAAAGGTGTATTTTTAAACTTTTGGGGTACGTGGTGTAAACCTTGTGAGAAAGAAATG
CCTTATATGAATGAACTATATCCAAAGTATAAAGAAAAAGGCGTTGAAATCATTGCGTTAGATGCAGATGAAACGGATAT
TGCTGTTAAGAATTTTGTGAAACAATACGATCTTAAGTTCCCCGTTGCAATCGATAAAGGTGGAGAAATTATAAAAACGT
ATGGAGTAATACCATTACCAACAAGCTTCTTGATTGATAAAGATGGTAAGGTGATTCAAGAGATTAAAGGTGAACAAACG
AAGGAACAATTGGAGGAGTATTTAAAGAAAATCACTCCGTAA

Upstream 100 bases:

>100_bases
CGCTAATCGATATTGTGAAAATTTCACCAGTGGAATGCTCCGCTGGTGATTTATTAAAAAATACATATATTCATCACTCG
TCGAAGAGAGGGGAGACAAT

Downstream 100 bases:

>100_bases
TAAAGAAAACCTTTACATACAAGGCGCTTACCTATAGTGCCTTCGGTTTAAAAATTCTGAGTATTGCGGTAACTTTAGGT
TAGAATATACAATAGTACAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEEKKIELKDFKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKFPVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQT
KEQLEEYLKKITP

Sequences:

>Translated_173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEEKKIELKDFKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKFPVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQT
KEQLEEYLKKITP
>Mature_173_residues
MKKNRLLFRVIILLILCGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEEKKIELKDFKGKGVFLNFWGTWCKPCEKEM
PYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKFPVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQT
KEQLEEYLKKITP

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=179, Percent_Identity=26.2569832402235, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 19987; Mature: 19987

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKNRLLFRVIILLILCGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEEKKIELKDFK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCHHHCCHHCCCC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQTKEQLEEYLKKITP
CEEECCCCCEEEECCCCCCCHHEEECCCCHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKNRLLFRVIILLILCGAVGFTLYQGYFSKEEKMEIGKEAPNFVVTDLEEKKIELKDFK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEEECCHHHCCHHCCCC
GKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVKQYDLKF
CCEEEEECCCCCCCCHHHCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCC
PVAIDKGGEIIKTYGVIPLPTSFLIDKDGKVIQEIKGEQTKEQLEEYLKKITP
CEEECCCCCEEEECCCCCCCHHEEECCCCHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA