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The map label for this gene is inlA [H]

Identifier: 222095062

GI number: 222095062

Start: 1391304

End: 1393589

Strand: Direct

Name: inlA [H]

Synonym: BCQ_1402

Alternate gene names: 222095062

Gene position: 1391304-1393589 (Clockwise)

Preceding gene: 222095061

Following gene: 222095063

Centisome position: 26.68

GC content: 31.93

Gene sequence:

>2286_bases
ATGAAGGCGCTAGTAGTAGCGACAACATTAGCAATTCCATTTGCTGCATACTCTACTCCAGCGTTAGCAGCAATAAAAAT
TGAAGCAAACCAATCGGTAGCGGCAGCTAGTGAACGTACATACGATACTGAGATTAAAATATATAAGGATCAAAAAGACG
AGCCATCTATGGTTTCTCAATATATAAAAGATCCTAAAGTAACGATTGCGGATGGGAAAAAAATTGTAACTGTAACAATG
CAAGATAGCGATTATTTTCAATACCTTAGAATAGAGGATAAAAACCAACCTGGCGTATTTCATGATGTGAAAGTTTTGTC
AGAAGATAAGAGGAAGAATGGAACGAAAGTAGTTCAATTTGAAATTGGCGAGTTTGAGAAGAAGCACAATATGCAAATGC
ATATACTTATTCCGGCTATTGGATATGATCACAAATATCAAGTTCAATTTGAAATTAAAGATCCAACTGTAGGTGACAAA
GAAACAGAGAAACGAGATGATAACTCTAATTCAGGCAATATGGAGACGGATCATCCAGTTGATAATCAAAATATGATAAC
AGATAATAAATTAAGAGAGCTTGTTAATAAAAAGGTATTTAATAGAAAAGATTTAAATACACCAATCACGAAAGAAGAGT
TATTACAAGTAAAGGACTTGTTTTTAAATACGAATGAGATACTGGATTATAGTGCATTAAAATATATGCCAAATTTAAAA
TCTTTAACAGTTGCGAATGCGAAGATAAAAGATCCATCATTCTTTACGAGCTTAAAACAATTGAAACATTTAGCTTTACG
TGGTAATGAATTTTCAGATGTAACACCACTTGTTAAGATGGATAATTTAGATTCTCTTGATTTAAGTAATAATAAAATTA
CGAACGTTGCACCACTAATTGAGATGAAAAATGTAAAAAGTTTATATTTATCAGGTAACCAAATAGAAGATGTAACAGCG
TTAGCGAAAATGGAACAACTAGATTACTTGAATTTAGCAAATAATAAAATTACGAATGTTGCGCCATTAAGCGCGTTGAA
AAATGTAACATATTTAACTTTAGCAGGTAATCAAATTGAAGATATTAAACCGTTATATTCATTACCTTTAAAAGACTTAG
TATTAACACGTAATAAAGTAAAAGATTTATCCGGTATTGAGCAAATGAAGCAATTAGAAGAATTGTGGATCGGGAAAAAT
GAAATAAAAGATGTTACTCCTCTAAGTAAGATGACACAGTTAAAACAATTACACTTACCTAACAATGAGTTAAAGGATAT
TACTCCATTATCAAGTCTAGTAAACTTACAAAAGCTTGATTTAGAAGCGAATTATATTTCAGACTTAACACCAGCTAGCA
ATTTGAAAAAGTTAGTATTCTTAAGTTTTGTTGCAAATGAAATTCGTGATGTTCGACCAGTTATAGAACTAAGTAAAACA
GCCTATATCAATGTTCAAAATCAAAAAGTATTTTTAGAGGAAACAGAAGTAAATAAAGAAGTAAAAGTACCTATATACGA
GAAAGATGGTAAAATCTCTACAAAAATTCGTTTAAAGAGCGAAGGTGGTACGTATAGTAATGATGCAGTTAAGTGGAGTA
CACCGGGTGAGAAAGTATATGAATTTGGTGTAAAAGATCCATTTGCGGATACAGGAATCTTCTTCACAGGATCTGTGATT
CAAAATGTGGTAGAAAGTAAAGAAGATAACACTTCTAAAGAAGACAATAATTCTAAAGAAGATGAAAAAGTAGGAGTAGT
AGAATTTAAAGATGTACCAAAAGGACATTGGTCAGAGGAAGCAATTCATTATTTAGCGAAAGAAAATATTTTTAAGGGAT
ATGGAAATGGACAATTTGGATTTGGGGATCGTATTACTCGTGGACAAGTTGCGTCTTTAGTACAAAGGTATTTGAAATTA
GAAAATAAAGTAGAGCAGAAAGAGAGATTTACAGATACGAAAGGACATATGTTTGAGCAAGATATTGCTACAGTTGCGCA
AGCTGGAATTATGCAAGGAGATGGTACTGGGGAGTTTCGTCCAGATGGAGTATTAACTCGATACGAAATGTCTGTAGTAT
TATATAAAGTATTTCAGCTAAAAGAAGATGAAAATAATAAAGTGAACTTTAATGATGTACCAACTGGTCATTGGGCAGAA
GAATATGTGAAAGCGTTAGCGGACAATAACATATCAAAAGGTGATGGAAAAGGAAACTTTTTAGGTGATGATTTTGTAAC
ACGTGAACAATATGCACAGTTCTTATATAACGCAATAATGAAATAA

Upstream 100 bases:

>100_bases
GATAATGATATTCATTATCATTTATTTATGAGTAATTGATAATGTTTATCAATTATAAAGATTATATATGATAGGGGATA
TTATTTTGAAAAAAAATTAT

Downstream 100 bases:

>100_bases
AAGATGAGAAAATACGTTATTCTTTGATTGAAAAAGAATAACGTATTTTTTATGTATAAAATGAAATAGTCAATATACAG
GAGTATAGACATATGAATAG

Product: internalin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MKALVVATTLAIPFAAYSTPALAAIKIEANQSVAAASERTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIADGKKIVTVTM
QDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGDK
ETEKRDDNSNSGNMETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKDLFLNTNEILDYSALKYMPNLK
SLTVANAKIKDPSFFTSLKQLKHLALRGNEFSDVTPLVKMDNLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTA
LAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKN
EIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFTGSVI
QNVVESKEDNTSKEDNNSKEDEKVGVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDRITRGQVASLVQRYLKL
ENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDENNKVNFNDVPTGHWAE
EYVKALADNNISKGDGKGNFLGDDFVTREQYAQFLYNAIMK

Sequences:

>Translated_761_residues
MKALVVATTLAIPFAAYSTPALAAIKIEANQSVAAASERTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIADGKKIVTVTM
QDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGDK
ETEKRDDNSNSGNMETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKDLFLNTNEILDYSALKYMPNLK
SLTVANAKIKDPSFFTSLKQLKHLALRGNEFSDVTPLVKMDNLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTA
LAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKN
EIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFTGSVI
QNVVESKEDNTSKEDNNSKEDEKVGVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDRITRGQVASLVQRYLKL
ENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDENNKVNFNDVPTGHWAE
EYVKALADNNISKGDGKGNFLGDDFVTREQYAQFLYNAIMK
>Mature_761_residues
MKALVVATTLAIPFAAYSTPALAAIKIEANQSVAAASERTYDTEIKIYKDQKDEPSMVSQYIKDPKVTIADGKKIVTVTM
QDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQFEIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGDK
ETEKRDDNSNSGNMETDHPVDNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKDLFLNTNEILDYSALKYMPNLK
SLTVANAKIKDPSFFTSLKQLKHLALRGNEFSDVTPLVKMDNLDSLDLSNNKITNVAPLIEMKNVKSLYLSGNQIEDVTA
LAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIEDIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKN
EIKDVTPLSKMTQLKQLHLPNNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVYEFGVKDPFADTGIFFTGSVI
QNVVESKEDNTSKEDNNSKEDEKVGVVEFKDVPKGHWSEEAIHYLAKENIFKGYGNGQFGFGDRITRGQVASLVQRYLKL
ENKVEQKERFTDTKGHMFEQDIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDENNKVNFNDVPTGHWAE
EYVKALADNNISKGDGKGNFLGDDFVTREQYAQFLYNAIMK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI21389483, Length=210, Percent_Identity=30, Blast_Score=87, Evalue=8e-17,
Organism=Homo sapiens, GI4506013, Length=225, Percent_Identity=29.3333333333333, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI21361633, Length=249, Percent_Identity=30.5220883534137, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI55743114, Length=142, Percent_Identity=33.8028169014084, Blast_Score=69, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531555, Length=220, Percent_Identity=28.6363636363636, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17554124, Length=231, Percent_Identity=29.4372294372294, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536161, Length=216, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71984630, Length=256, Percent_Identity=28.515625, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322655, Length=223, Percent_Identity=29.5964125560538, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21358617, Length=211, Percent_Identity=27.4881516587678, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24658034, Length=182, Percent_Identity=29.6703296703297, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17136436, Length=297, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 86193; Mature: 86193

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50978 NEAT ; PS01072 SLH_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVVATTLAIPFAAYSTPALAAIKIEANQSVAAASERTYDTEIKIYKDQKDEPSMVSQ
CCEEEEEHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEEECCCCCHHHHHH
YIKDPKVTIADGKKIVTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQF
HHCCCCEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEE
EIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGDKETEKRDDNSNSGNMETDHPV
ECCCHHHHCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCC
DNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKDLFLNTNEILDYSALKYMPNLK
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SLTVANAKIKDPSFFTSLKQLKHLALRGNEFSDVTPLVKMDNLDSLDLSNNKITNVAPLI
CEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHH
EMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIE
HHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEEECCCHH
DIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLKQLHLP
HCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCC
NNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
CCCCHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVY
EEEEEECCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCHHHH
EFGVKDPFADTGIFFTGSVIQNVVESKEDNTSKEDNNSKEDEKVGVVEFKDVPKGHWSEE
CCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCHHCCCEEEECCCCCCCCHHH
AIHYLAKENIFKGYGNGQFGFGDRITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQ
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDENNKVNFNDVPTGHWAE
HHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHH
EYVKALADNNISKGDGKGNFLGDDFVTREQYAQFLYNAIMK
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKALVVATTLAIPFAAYSTPALAAIKIEANQSVAAASERTYDTEIKIYKDQKDEPSMVSQ
CCEEEEEHHHHHHHHHCCCCCEEEEEEECCCCHHHHCCCCCCCEEEEEECCCCCHHHHHH
YIKDPKVTIADGKKIVTVTMQDSDYFQYLRIEDKNQPGVFHDVKVLSEDKRKNGTKVVQF
HHCCCCEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEE
EIGEFEKKHNMQMHILIPAIGYDHKYQVQFEIKDPTVGDKETEKRDDNSNSGNMETDHPV
ECCCHHHHCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCC
DNQNMITDNKLRELVNKKVFNRKDLNTPITKEELLQVKDLFLNTNEILDYSALKYMPNLK
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
SLTVANAKIKDPSFFTSLKQLKHLALRGNEFSDVTPLVKMDNLDSLDLSNNKITNVAPLI
CEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHH
EMKNVKSLYLSGNQIEDVTALAKMEQLDYLNLANNKITNVAPLSALKNVTYLTLAGNQIE
HHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEEEECCCHH
DIKPLYSLPLKDLVLTRNKVKDLSGIEQMKQLEELWIGKNEIKDVTPLSKMTQLKQLHLP
HCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCC
NNELKDITPLSSLVNLQKLDLEANYISDLTPASNLKKLVFLSFVANEIRDVRPVIELSKT
CCCCHHCCHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
AYINVQNQKVFLEETEVNKEVKVPIYEKDGKISTKIRLKSEGGTYSNDAVKWSTPGEKVY
EEEEEECCEEEEEECCCCCEEEEEEEECCCCEEEEEEEECCCCCCCCCCEEECCCCHHHH
EFGVKDPFADTGIFFTGSVIQNVVESKEDNTSKEDNNSKEDEKVGVVEFKDVPKGHWSEE
CCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCHHCCCEEEECCCCCCCCHHH
AIHYLAKENIFKGYGNGQFGFGDRITRGQVASLVQRYLKLENKVEQKERFTDTKGHMFEQ
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
DIATVAQAGIMQGDGTGEFRPDGVLTRYEMSVVLYKVFQLKEDENNKVNFNDVPTGHWAE
HHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHH
EYVKALADNNISKGDGKGNFLGDDFVTREQYAQFLYNAIMK
HHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]