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The map label for this gene is phnW [H]

Identifier: 222095059

GI number: 222095059

Start: 1387756

End: 1388853

Strand: Direct

Name: phnW [H]

Synonym: BCQ_1399

Alternate gene names: 222095059

Gene position: 1387756-1388853 (Clockwise)

Preceding gene: 222095058

Following gene: 222095060

Centisome position: 26.61

GC content: 35.06

Gene sequence:

>1098_bases
ATGACTGAAAATCACTACTTATTATTAACGCCAGGACCATTAACGACAACAAAAACAGTAAAAGAAGTTATGCTATACGA
TTGGTGTACGTGGGATGTTGAATATAACATGATGGTGCAACAGGTAAGAGCTAAACTTGTATCGTTAGCAACGAAGGAAG
AAGAGAGATATACAACAGTATTAATGCAAGGAAGCGGTACTTTTTCAGTTGAAGCAGTAATCGGTTCTGTCATTCCAAAA
AACGGAAAGATGCTTGTTTGTACAAATGGTGCGTATGGTAAGAGAATTGTACAAATGGCAGAGATGTTACATATAGATGT
GGTGGTCAGTCAAACAGAAGAGTGGGAGCCTACTAATATTGTAGAAGTAGAAAAGATATTACAACAAGATAAAGAGATTA
CACATATTGCAGTTGTTCATTGTGAAACAACAACAGGTATTATCAATCCAATTGTAGATGTATGTAAATTAGGGAAGCAA
TACGGAAAAGTAACACTAGTTGATGCAATGAGTAGTTTTGGTGGTATTGAAATAGATATCGCTGAGTTGCAAATTGACTT
TCTAATTAGTAGTGCGAATAAATGTATTCAAGGGGTTCCAGGGTTCGGATTTGTTATTGCAAAGCGCGATGAATTGTTGA
AATGTAAAGGGCAGGCACGTTCATTATCTTTAGATTTATACGATCAATGGGAAACAATGGAAAATCAAAATGGGAAATGG
CGTTTTACATCACCTACACATGTTGTACACGCTTTTTATCAAGCACTACTTGAATTAGAAAAAGAGGGCGGAGTAAAAGC
ACGTTACAATCGATATGATAACAATCAAAAACTATTAGTGAATCGAATGAGAGAAATCGGATTTAAGCCACTAGTAGATG
AAAAATATCAATCGCCTATTATTACATCTTTCATTTATCCAGAAGAATGGTTTGATTTTGAGCAATTATACAATGAATTA
AAGCGGGATGGATTTGTTATATATCCAGGTAAAATTTCAAAAGTAGATACATTCCGCATTGGAAATATCGGTGATGTACA
TGAGGCAGATATTCATCGCTTAGTTGATAGTATCGCTAAAGGAGTTGTTATAGGTTGA

Upstream 100 bases:

>100_bases
CGGGGCTCATTTTACAATTGAAACGATGCAGGGACTCGAAAACGTAATTGAACAGATTGAGAAACAAGAATTTATTATTT
CATAAAAGGGGAATAGGATC

Downstream 100 bases:

>100_bases
AAGTATTTTGCTTAGGTGGAGCAGGTAAAATTTGTCGTGAAGCAATTTTAGATTTAGTGCAATTTTCATCTTTTGAGACG
ATTACAGTAGCAGATTTTAA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTVLMQGSGTFSVEAVIGSVIPK
NGKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPIITSFIYPEEWFDFEQLYNEL
KRDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAKGVVIG

Sequences:

>Translated_365_residues
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTVLMQGSGTFSVEAVIGSVIPK
NGKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQ
YGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
RFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPIITSFIYPEEWFDFEQLYNEL
KRDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAKGVVIG
>Mature_364_residues
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTVLMQGSGTFSVEAVIGSVIPKN
GKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQY
GKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKWR
FTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPIITSFIYPEEWFDFEQLYNELK
RDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAKGVVIG

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=264, Percent_Identity=25, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17536281, Length=364, Percent_Identity=21.978021978022, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 41446; Mature: 41315

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTV
CCCCCEEEEECCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHCCCC
ITSFIYPEEWFDFEQLYNELKRDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAK
EEEECCCHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
GVVIG
CCCCC
>Mature Secondary Structure 
TENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNMMVQQVRAKLVSLATKEEERYTTV
CCCCEEEEECCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEE
LMQGSGTFSVEAVIGSVIPKNGKMLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNI
EEECCCCEEHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHEEEEECCCCCCCCCH
VEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDI
HHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
AELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKW
EHEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCEEEEEHHHHHHHHCCCCCCE
RFTSPTHVVHAFYQALLELEKEGGVKARYNRYDNNQKLLVNRMREIGFKPLVDEKYQSPI
EECCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCHHHCCCC
ITSFIYPEEWFDFEQLYNELKRDGFVIYPGKISKVDTFRIGNIGDVHEADIHRLVDSIAK
EEEECCCHHCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHC
GVVIG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA